Chemotherapy‑induced fulminant acute pancreatitis in pancreatic carcinoma: A case report

Lu,Linghui; Lou,Yanni; Tan,Huangying

doi:10.3892/ol.2014.2316

September-2014 Volume 8 Issue 3

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September-2014 Volume 8 Issue 3

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Case Report

Chemotherapy‑induced fulminant acute pancreatitis in pancreatic carcinoma: A case report

Authors:
- Linghui Lu
- Yanni Lou
- Huangying Tan
View Affiliations / Copyright

Affiliations: Department of Traditional Chinese Medicine Oncology, China‑Japan Friendship Hospital, Beijing 100029, P.R. China
Pages: 1143-1146
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Published online on: July 4, 2014

https://doi.org/10.3892/ol.2014.2316
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Abstract

Cases of chemotherapy‑induced pancreatitis are rarely reported and among those diagnosed, the majority are mild and self‑limiting. However, no previous cases of fulminant acute pancreatitis (FAP) induced by chemotherapeutic agents have been reported. The current study presents a case of FAP in a 62‑year‑old female on gemcitabine and capecitabine therapy. The patient was admitted to the China‑Japan Friendship Hospital (Beijing, China) with the symptoms of acute pancreatitis two days after the completion of the first cycle of chemotherapy. Shock, hypoxemia and acute renal failure supervened, which resulted in mortality. As the common etiologies of pancreatitis were eliminated, a correlation between the incidence of FAP, and pancreatic cancer or chemotherapy, or both was suspected. Clinicians should be aware of this potential adverse effect when prescribing chemotherapeutic agents, particularly in patients with pre‑existing risk factors for pancreatitis.

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Journals

International Journal of Molecular Medicine

International Journal of Oncology

Molecular Medicine Reports

Oncology Reports

Experimental and Therapeutic Medicine

Oncology Letters

Biomedical Reports

Molecular and Clinical Oncology

World Academy of Sciences Journal

International Journal of Functional Nutrition

International Journal of Epigenetics

Medicine International

Chemotherapy‑induced fulminant acute pancreatitis in pancreatic carcinoma: A case report

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Abstract

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