Basaloid squamous cell carcinoma of the maxillary gingiva: A case report and review of the literature

Xie,Shule; Bredell,Marius; Yang,Hongyu; Shen,Shiyue; Yang,Huijun

doi:10.3892/ol.2014.2318

September-2014 Volume 8 Issue 3

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September-2014 Volume 8 Issue 3

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Case Report

Basaloid squamous cell carcinoma of the maxillary gingiva: A case report and review of the literature

Authors:
- Shule Xie
- Marius Bredell
- Hongyu Yang
- Shiyue Shen
- Huijun Yang
View Affiliations / Copyright

Affiliations: Department of Oral and Maxillofacial Surgery, Peking University, Shenzhen Hospital, Shenzhen, Guangdong 518001, P.R. China, Department of Cranio‑Maxillofacial and Oral Surgery, University Hospital of Zürich, Zürich CH‑8091, Switzerland
Pages: 1287-1290
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Published online on: July 4, 2014

https://doi.org/10.3892/ol.2014.2318
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Abstract

Basaloid squamous cell carcinoma (BSCC) is a rare, but distinct histologic variant of squamous cell carcinoma in the head and neck region. It is considered to have a poor prognosis due to its aggressive behavior and tendency to metastasize. The usual sites of BSCC are the floor of the mouth, hypopharynx and base of the tongue, and according to the English‑language literature its presentation in the gingiva is somewhat uncommon. In the current report, the unusual case of a 40‑year‑old male is presented; the patient exhibited a painless irregular mass in the maxillary gingiva, which infiltrated the maxillary sinus, as observed by computed tomography. Hematoxylin and eosin‑stained sections revealed a diagnosis of BSCC with typical central necrosis in the cancer nests, which contained basaloid and squamous cells. Immunohistochemistry revealed that p63 was weakly positive, high molecular weight cytokeratin (CK) was focally positive, and S‑100, CK7, CK14 and vimentin were negative. It must be noted that histopathology results may be incorrectly interpreted as adenoid cystic carcinoma, undifferentiated carcinoma and basal cell adenocarcinoma.

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Journals

International Journal of Molecular Medicine

International Journal of Oncology

Molecular Medicine Reports

Oncology Reports

Experimental and Therapeutic Medicine

Oncology Letters

Biomedical Reports

Molecular and Clinical Oncology

World Academy of Sciences Journal

International Journal of Functional Nutrition

International Journal of Epigenetics

Medicine International

Basaloid squamous cell carcinoma of the maxillary gingiva: A case report and review of the literature

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