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Article

Dosimetric comparison of intensity modulated and volumetric arc radiation therapy for gastric cancer

  • Authors:
    • Zhiping Li
    • Jianshuang Zeng
    • Zi Wang
    • Hong Zhu
    • Yuquan Wei
  • View Affiliations / Copyright

    Affiliations: Department of Abdominal Oncology, Cancer Center of West China Hospital, Sichuan University, Chengdu, Sichuan 610041, P.R. China
  • Pages: 1427-1434
    |
    Published online on: July 18, 2014
       https://doi.org/10.3892/ol.2014.2363
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Abstract

The aim of the present study was to compare radiotherapy treatment plans for gastric cancer using intensity‑modulated radiotherapy (IMRT) and single/double‑arc volumetric modulated arc therapy (SA/DA‑VMAT) delivery techniques. A total of 29 postoperative gastric cancer patients were enrolled in this study and each patient was scheduled 5‑field IMRT (5F‑IMRT), 7‑field IMRT (7F‑IMRT), SA‑VMAT and DA‑VMAT techniques. Dose‑volume histogram statistics, conformal index (CI), homogeneity index (HI) and monitor units (MUs) were analyzed to compare treatment plans. The DA‑VMAT plans exceeded the other three methods in terms of planning tumor volume dose and organs at risk in the kidneys, but not in the liver. DA‑VMAT exhibited a better mean CI (0.87±0.03) and HI (0.10±0.01) than the other techniques. In addition, for the kidneys the dose sparing (V13, V18 and mean kidney dose) was improved by DA‑VMAT plans. Similar results were observed for MUs. However, 5F‑IMRT showed a marginal advantage in V30 and mean dose in normal liver when compared with DA‑VMAT. The results of this study suggest that DA‑VMAT provides improved tumor coverage when compared with 5F‑IMRT, 7F‑IMRT and SA‑VMAT; however, DA‑VMAT exhibits no advantage in liver protection when compared with 5F‑IMRT. Further studies are required to establish differences in treatment outcomes among the four technologies.
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Copy and paste a formatted citation
Spandidos Publications style
Li Z, Zeng J, Wang Z, Zhu H and Wei Y: Dosimetric comparison of intensity modulated and volumetric arc radiation therapy for gastric cancer. Oncol Lett 8: 1427-1434, 2014.
APA
Li, Z., Zeng, J., Wang, Z., Zhu, H., & Wei, Y. (2014). Dosimetric comparison of intensity modulated and volumetric arc radiation therapy for gastric cancer. Oncology Letters, 8, 1427-1434. https://doi.org/10.3892/ol.2014.2363
MLA
Li, Z., Zeng, J., Wang, Z., Zhu, H., Wei, Y."Dosimetric comparison of intensity modulated and volumetric arc radiation therapy for gastric cancer". Oncology Letters 8.4 (2014): 1427-1434.
Chicago
Li, Z., Zeng, J., Wang, Z., Zhu, H., Wei, Y."Dosimetric comparison of intensity modulated and volumetric arc radiation therapy for gastric cancer". Oncology Letters 8, no. 4 (2014): 1427-1434. https://doi.org/10.3892/ol.2014.2363
Copy and paste a formatted citation
x
Spandidos Publications style
Li Z, Zeng J, Wang Z, Zhu H and Wei Y: Dosimetric comparison of intensity modulated and volumetric arc radiation therapy for gastric cancer. Oncol Lett 8: 1427-1434, 2014.
APA
Li, Z., Zeng, J., Wang, Z., Zhu, H., & Wei, Y. (2014). Dosimetric comparison of intensity modulated and volumetric arc radiation therapy for gastric cancer. Oncology Letters, 8, 1427-1434. https://doi.org/10.3892/ol.2014.2363
MLA
Li, Z., Zeng, J., Wang, Z., Zhu, H., Wei, Y."Dosimetric comparison of intensity modulated and volumetric arc radiation therapy for gastric cancer". Oncology Letters 8.4 (2014): 1427-1434.
Chicago
Li, Z., Zeng, J., Wang, Z., Zhu, H., Wei, Y."Dosimetric comparison of intensity modulated and volumetric arc radiation therapy for gastric cancer". Oncology Letters 8, no. 4 (2014): 1427-1434. https://doi.org/10.3892/ol.2014.2363
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