Abdominal actinomycosis with multiple myeloma: A case report

Ercolak,Vehbi; Paydas,Semra; Ergin,Melek; Ates,Berna  T.; Duman,Berna  B.; Gunaldi,Meral; Afsar,Cigdem  U.

doi:10.3892/ol.2014.2375

Abdominal actinomycosis with multiple myeloma: A case report

Authors:
- Vehbi Ercolak
- Semra Paydas
- Melek Ergin
- Berna T. Ates
- Berna B. Duman
- Meral Gunaldi
- Cigdem U. Afsar
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Affiliations: Department of Medical Oncology, Faculty of Medicine, Harran University, Şanlıurfa 63300, Turkey, Department of Oncology, Faculty of Medicine, Çukurova University, Adana 01330, Turkey, Department of Pathology, Faculty of Medicine, Çukurova University, Adana 01330, Turkey, Division of Medical Oncology, Adana Numune Research and Training Hospital, Adana 01030, Turkey
Published online on: July 23, 2014 https://doi.org/10.3892/ol.2014.2375
Pages: 1876-1878

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Abstract

Actinomycosis is a chronic suppurative infection, for which immune suppression is a predisposing factor. In unusual cases, this disease may present as an abdominal wall involvement simulating a soft tissue tumor as seen in the present case. The presented patient had no signs of trauma or surgical approach and the pathology was considered to be a primary abdominal wall actinomycosis. Preoperative diagnosis is difficult due to the nonspecific nature of clinical presentation, radiographic and laboratory findings. Surgery combined with antibiotic treatment is a curative approach for this relatively rare infection. Surgeons must be aware of this disease in order to ensure correct diagnosis and to prevent performing any unnecessary procedures. The present study describes a case of abdominal actinomycosis with multiple myeloma, together with a review of important points related to this disease.

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1	Russo TA: Agents of actinomycosis. Principle and practice of infectious diseases. Mandell GL, Bennet JE and Dolin R: Churchill Livingstone; New York: pp. 2924–2934. 2005
2	Weese WC and Smith IM: A study of 57 cases of actinomycosis over a 36-year period. A diagnostic ‘failure’ with good prognosis after treatment. Arch Int Med. 135:1562–1568. 1975.
3	Akgün Y: Actinomyces species. Infection Diseases and Microbiology. Topçu AW, Söyletir G and Doğanay M: 2nd edition. Nobel Medical Publishers; İstanbul: pp. 1701–1705. 2002, (In Turkish).
4	Hocaoğlu B, Fikretler M, Aras A and Gürkaynak GŞ: Omental actinomycosis with abdominal wall invasion treated by penicillin G: A case report. Klimik Journal. 24:135–137. 2011.(In Turkish).
5	Wang YH, Tsai HC, Lee SS, et al: Clinical manifestations of actinomycosis in Southern Taiwan. J Microbiol Immunol Infect. 40:487–492. 2007.
6	Laurent T, de Grandi P and Schnyder P: Abdominal actinomycosis associated with intrauterine device: CT features. Eur Radiol. 6:670–673. 1996.
7	Bennhoff DF: Actinomycosis: diagnostic and therapeutic considerations and a review of 32 cases. Laryngoscope. 94:1198–1217. 1984.
8	Dominguez DC and Antony SJ: Actinomyces and Nocardia infections in immunocompromised and non immunocompromised patients. J Natl Med Assoc. 91:35–39. 1999.
9	Cocuroccia B, Gubinelli E, Fazio M and Girolomoni G: Primary cutaneous actinomycosis of the forehead. J Eur Acad Dermatol Venereol. 17:331–333. 2003.
10	Acquaro P, Tagliabue F, Confalonieri G, Faccioli P and Costa M: Abdominal wall actinomycosis simulating a malignant neoplasm: Case report and review of the literature. World J Gastrointest Surg. 2:247–250. 2010.
11	Simsek A, Perek A, Cakcak IE and Durgun AV: Pelvic actinomycosis presenting as a malignant pelvic mass: a case report. J Med Case Rep. 5:402011.
12	Wang HK, Sheng WH, Hung CC, et al: Hepatosplenic actinomycosis in an immunocompetent patient. J Formos Med Assoc. 111:228–231. 2012.
13	Filipović B, Milinić N, Nikolić G and Ranthelović T: Primary actinomycosis of the anterior abdominal wall: case report and review of the literature. J Gastroenterol Hepatol. 20:517–520. 2005.
14	Kaya D, Demirezen Ş and Beksac MS: Actinomycosis: An overview. Türkiye Klinikleri J Med Sci. 29:510–519. 2009.(In Turkish).
15	Erkaya S, Kutlar IA, Kosan I, et al: Pelvic actinomycosis (presentation of two cases). TKlin J Gynecol Obst. 9:284–287. 1999.(In Turkish).
16	Williams CE, Lamb GH and Lewis-Jones HG: Pelvic actinomycosis: beware the intrauterine contraceptive device. Br J Radiol. 63:134–137. 1990.
17	Koren R, Dekel Y, Ramadan E, Veltman V and Dreznik V: Periappendiceal actinomycosis mimicking malignancy report of a case. Pathol Res Pract. 198:441–443. 2002.
18	Dogan NU, Salman MC, Gultekin M, Kucukali T and Ayhan A: Bilateral actinomyces abscesses mimicking pelvic malignancy. Int J Gynaecol Obstet. 94:58–59. 2006.
19	Şakrak O, Müderrisoğlu I, Bedirli A, İnce O and Canöz O: Abdominal actinomycosis appearing as an intra-abdominal tumoral mass. Turk J Med Sci. 33:53–55. 2003.
20	Marella VK, Hakimian O, Wise GJ and Silver DA: Pelvic actinomycosis: Urologic perspective. Int Braz J Urol. 30:367–376. 2004.
21	Gotoh S, Kura N, Nagahama K, et al: Actinomycosis of urachal remnants. J Urol. 140:1534–1535. 1988.
22	Pusiol T, Morichetti D, Pedrazzani C and Ricci F: Abdominal-pelvic actinomycosis mimicking malignant neoplasm. Infect Dis Obstet Gynecol. 2011:7470592011.
23	Wagenlehner FM, Mohren B, Naber KG and Männl HF: Abdominal actinomycosis. Clin Microbiol Infect. 9:881–885. 2003.
24	Das N, Lee J, Madden M, et al: A rare case of abdominal actinomycosis presenting as an inflammatory pseudotumour. Int J Colorectal Dis. 21:483–484. 2006.
25	Chaitra V, Rajalakshmi T, Mohanty S, et al: Actinomycosis in urachal remnants: A rare cause of pseudotumor. Indian J Urol. 27:545–546. 2011.
26	Ozcan R, Mammadov E, Aydın E, et al: Actinomycosis presenting as an abdominal mass in a child. APSP J Case Rep. 2:42011.
27	Mert A, Tabak F, Dumankar A, et al: A case of pelvic actinomycosis treated with penicillin. Klimik Journal. 9:68–69. 1996.(In Turkish).