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Oncology Letters
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Print ISSN: 1792-1074 Online ISSN: 1792-1082
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December-2014 Volume 8 Issue 6

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International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

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International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

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Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

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Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

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Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

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Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

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Case Report

Giant cell tumor of the clivus: A case report and review of the literature

  • Authors:
    • Jing Zhao
    • Tao Qian
    • Zheng Zhi
    • Qingxia Li
    • Lin Kang
    • Juan Wang
    • Aixia Sui
    • Na Li
    • Hongtao Zhang
  • View Affiliations / Copyright

    Affiliations: The First Department of Oncology, Hebei General Hospital, Shijiazhuang, Hebei 050051, P.R. China, Department of Neurosurgery, Hebei General Hospital, Shijiazhuang, Hebei 050051, P.R. China, Department of History and Literature, Hebei University of Traditional Chinese Medicine, Shijiazhuang, Hebei 050200, P.R. China, Department of Pathology, Hebei General Hospital, Shijiazhuang, Hebei 050051, P.R. China
  • Pages: 2782-2786
    |
    Published online on: September 12, 2014
       https://doi.org/10.3892/ol.2014.2528
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Abstract

Giant cell tumors (GCTs) mainly occur in metaphyses of long bones and are generally considered histologically benign; however, GCTs may be locally aggressive with a high rate of local recurrence and exhibit the potential for distant metastasis. Primary GCT of the clivus is extremely rare and is easily misdiagnosed and, thus, treatment remains controversial. The present report describes the case of a 22‑year‑old male with GCT located in the skull base originating from the clivus, with the involvement of multiple cranial nerves, which was successfully treated with transnasal transsphenoidal surgery following adjuvant radiotherapy and intravenous bisphosphonate administration. The patient remains symptom free at two years of follow‑up. This report contributes to the limited literature regarding GCTs of the skull.
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Copy and paste a formatted citation
Spandidos Publications style
Zhao J, Qian T, Zhi Z, Li Q, Kang L, Wang J, Sui A, Li N and Zhang H: Giant cell tumor of the clivus: A case report and review of the literature. Oncol Lett 8: 2782-2786, 2014.
APA
Zhao, J., Qian, T., Zhi, Z., Li, Q., Kang, L., Wang, J. ... Zhang, H. (2014). Giant cell tumor of the clivus: A case report and review of the literature. Oncology Letters, 8, 2782-2786. https://doi.org/10.3892/ol.2014.2528
MLA
Zhao, J., Qian, T., Zhi, Z., Li, Q., Kang, L., Wang, J., Sui, A., Li, N., Zhang, H."Giant cell tumor of the clivus: A case report and review of the literature". Oncology Letters 8.6 (2014): 2782-2786.
Chicago
Zhao, J., Qian, T., Zhi, Z., Li, Q., Kang, L., Wang, J., Sui, A., Li, N., Zhang, H."Giant cell tumor of the clivus: A case report and review of the literature". Oncology Letters 8, no. 6 (2014): 2782-2786. https://doi.org/10.3892/ol.2014.2528
Copy and paste a formatted citation
x
Spandidos Publications style
Zhao J, Qian T, Zhi Z, Li Q, Kang L, Wang J, Sui A, Li N and Zhang H: Giant cell tumor of the clivus: A case report and review of the literature. Oncol Lett 8: 2782-2786, 2014.
APA
Zhao, J., Qian, T., Zhi, Z., Li, Q., Kang, L., Wang, J. ... Zhang, H. (2014). Giant cell tumor of the clivus: A case report and review of the literature. Oncology Letters, 8, 2782-2786. https://doi.org/10.3892/ol.2014.2528
MLA
Zhao, J., Qian, T., Zhi, Z., Li, Q., Kang, L., Wang, J., Sui, A., Li, N., Zhang, H."Giant cell tumor of the clivus: A case report and review of the literature". Oncology Letters 8.6 (2014): 2782-2786.
Chicago
Zhao, J., Qian, T., Zhi, Z., Li, Q., Kang, L., Wang, J., Sui, A., Li, N., Zhang, H."Giant cell tumor of the clivus: A case report and review of the literature". Oncology Letters 8, no. 6 (2014): 2782-2786. https://doi.org/10.3892/ol.2014.2528
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