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Article

Preoperative diagnosis and staging of rectal cancer using diffusion‑weighted and water imaging combined with dynamic contrast‑enhanced scanning

  • Authors:
    • Qili Zhao
    • Lijian Liu
    • Qiuyan Wang
    • Zexia Liang
    • Gaofeng Shi
  • View Affiliations / Copyright

    Affiliations: Department of Magnetic Resonance and Computed Tomography, The People's Hospital of Langfang City, Langfang, Hebei 065000, P.R. China, Department of Magnetic Resonance and Computed Tomography, The Fourth Hospital of Hebei Medical University, Shijiazhuang, Hebei 050019, P.R. China
  • Pages: 2734-2740
    |
    Published online on: October 9, 2014
       https://doi.org/10.3892/ol.2014.2590
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Abstract

The aim of the present study was to evaluate the value of diffusion‑weighted imaging (DWI) and water imaging combined with dynamic contrast‑enhanced scanning for the preoperative diagnosis and staging of rectal cancer. In total, 72 patients with pathologically confirmed rectal cancer were selected for examination using magnetic resonance imaging (MRI) with phased‑array coils, DWI, water imaging and dynamic contrast‑enhanced scanning. The patients were divided into two groups, experimental (simple enhanced scanning plus diffusion combined with water imaging) and control (simple enhanced scanning), for the pathological observations. The sensitivity, specificity and accuracy for the T staging of the carcinomas using scan enhancement with DWI and the evaluation of cancer using water imaging were 98.5% (65/66), 66.7% (4/6) and 95.8% (69/72), respectively, and the accuracy for N staging was 89%. Whereas, the sensitivity, specificity and accuracy for the T staging of the carcinomas using simple scan enhancement were 85.7% (42/49), 78.3% (18/23) and 83.3% (60/72), respectively, and the accuracy for N staging was 61%. Therefore, the combination of multiple MRI techniques may be of high value for the early diagnosis and exact staging of rectal cancer.
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1 

Kirkham A, Brown G, Williams GT, et al: High-resolution MRI of the anatomy important in total mesorectal excision of the rectum. AJR Am J Roentgenol. 182:431–439. 2011.

2 

You W, Jin F, Gridley G, et al: Trends in colorectal cancer rate, in urban shanghai, 1972–1996, in relation to dietary changes. Ann Epidemiol. 10:4692000.

3 

Zhang YL, Zhang ZS, Wu BP and Zhou DY: Early diagnosis for colorectal Cancer in China. World J Gastroenterol. 8:21–25. 2008.

4 

Berlin JW, Gore RM, Yaghmai V, Newmark GM and Miller FH: Staging of colorectal cancer. Semin Roentgenol. 35:370–384. 2009.

5 

Low RN, McCue M, Barone R, Saleh F and Song T: MR staging of primary colorectal carcinoma: comparison with surgical and histopathologic findings. Abdom Imaging. 28:784–793. 2009.

6 

Greene FL, Page DL, Fleming I, et al: AJCC Cancer Staging Manual. 6th edition. Springer-Verlag; New York, NY: 2002

7 

Brown G, Radcliffe AG, Newcombe RG, Dallimore NS, Bourne MW and Williams GT: Preoperative assessment of prognostic factors in rectal cancer using high-resolution magnetic resonance imaging. Br J Surg. 90:355–364. 2011.

8 

Kim NK, Kim MJ, Park JK, Park SI and Min JS: Preoperative staging of rectal cancer with MRI accuracy and clinical usefulness. Ann Surg Oncol. 7:732–737. 2009.

9 

Klessen C, Rogalla P and Taupitz M: Local staging of rectal cancer: the current role of MRI. Eur Radiol. 17:379–389. 2007.

10 

Blomqvist L: Preoperative staging of colorectal cancer-computed tomography and magnetic resonance imaging. Scand J Surg. 92:35–43. 2003.

11 

Brown G, Richards CJ, Bourne MW, et al: Morphologic predictors of lymph node status in rectal cancer with use of high-spatial-resolution MR imaging with histopathologic comparison. Radiology. 227:371–337. 2008.

12 

Havenga K, Enker WE, Norstein J, et al: Improved survival and local control after totalmesorectal excision or D3 lymphadenectomy in the treatment of primary rectal cancer: an international analysis of 1411 patients. Eur J Surg Oncol. 25:368–374. 2009.

13 

Gualdi GF, Casciani E, Guadalaxara A, et al: Local staging of rectal cancer with transrectal ultrasound and endorectal magnetic resonance imaging: Comparison with histologic findings. Dis Colon Rectum. 43:338–345. 2010.

14 

Kim NK, Kim MJ, Park JK, Park SI and Min JS: Preoperative staging of rectal cancer with MRI: accuracy and clinical usefulness. An Surg Oncol. 7:732–737. 2008.

15 

Kim MJ, Park JS, Park SI, et al: Accuracy in differentiation of mucinous and nonmucinous rectal carcinoma on MR imaging. J Comput Assist Tomogr. 27:48–55. 2007.

16 

Beets-Tan RG, Beets GL, Vliegen RF, et al: Accuracy of magnetic resonance imaging in prediction of tumour-free resection margin in rectal cancer surgery. Lancet. 357:497–504. 2010.

17 

Tsushima Y, Takano A, Taketomi-Takahashi A and Endo K: Body diffusion-weighted MR imaging using high b-value for malignant tumor screening: usefulness and necessity of referring to T2-weighted images and creating fusion images. Acad Radiol. 14:643–650. 2007.

18 

Sugita R, Yamazaki T, Furuta A, Itoh K, Fujita N and Takahashi S: High b-value diffusion-weighted MRI for detecting gallbladder carcinoma: preliminary study and results. Eur Radiol. 19:1794–1798. 2009.

19 

Hosonuma T, Tozaki M, Ichiba N, et al: Clinical usefulness of diffusion-weighted imaging using low and high b-values to detect rectal cancer. Magn Reson Med Sci. 5:173–177. 2006.

20 

Rao SX, Zeng MS, Chen CZ, et al: The value of diffusion-weighted imaging in combination with T2-weighted imaging for rectal cancer detection. Eur J Radiol. 65:299–303. 2008.

21 

Ichikawa T, Erturk SM, Motosugi U, Sou H, Iino H, Araki T and Fujii H: High-B-value diffusion-weighted MRI in colorectal cancer. AJR Am J Roentgenol. 187:181–184. 2006.

22 

Tu XH, Li CJ, Ma M, et al: Application of magnetic resonance hydrography in diagnosis of rectal carcinoma. Zhonghua Xiao Hua Wai Ke Za Zhi. 5:330–332. 2007.

23 

Pegios W, Vogl J, Mack MG, et al: MRI diagnosis and staging of rectal carcinoma. Abdom Imaging. 21:211–218. 1996.

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Copy and paste a formatted citation
Spandidos Publications style
Zhao Q, Liu L, Wang Q, Liang Z and Shi G: Preoperative diagnosis and staging of rectal cancer using diffusion‑weighted and water imaging combined with dynamic contrast‑enhanced scanning. Oncol Lett 8: 2734-2740, 2014.
APA
Zhao, Q., Liu, L., Wang, Q., Liang, Z., & Shi, G. (2014). Preoperative diagnosis and staging of rectal cancer using diffusion‑weighted and water imaging combined with dynamic contrast‑enhanced scanning. Oncology Letters, 8, 2734-2740. https://doi.org/10.3892/ol.2014.2590
MLA
Zhao, Q., Liu, L., Wang, Q., Liang, Z., Shi, G."Preoperative diagnosis and staging of rectal cancer using diffusion‑weighted and water imaging combined with dynamic contrast‑enhanced scanning". Oncology Letters 8.6 (2014): 2734-2740.
Chicago
Zhao, Q., Liu, L., Wang, Q., Liang, Z., Shi, G."Preoperative diagnosis and staging of rectal cancer using diffusion‑weighted and water imaging combined with dynamic contrast‑enhanced scanning". Oncology Letters 8, no. 6 (2014): 2734-2740. https://doi.org/10.3892/ol.2014.2590
Copy and paste a formatted citation
x
Spandidos Publications style
Zhao Q, Liu L, Wang Q, Liang Z and Shi G: Preoperative diagnosis and staging of rectal cancer using diffusion‑weighted and water imaging combined with dynamic contrast‑enhanced scanning. Oncol Lett 8: 2734-2740, 2014.
APA
Zhao, Q., Liu, L., Wang, Q., Liang, Z., & Shi, G. (2014). Preoperative diagnosis and staging of rectal cancer using diffusion‑weighted and water imaging combined with dynamic contrast‑enhanced scanning. Oncology Letters, 8, 2734-2740. https://doi.org/10.3892/ol.2014.2590
MLA
Zhao, Q., Liu, L., Wang, Q., Liang, Z., Shi, G."Preoperative diagnosis and staging of rectal cancer using diffusion‑weighted and water imaging combined with dynamic contrast‑enhanced scanning". Oncology Letters 8.6 (2014): 2734-2740.
Chicago
Zhao, Q., Liu, L., Wang, Q., Liang, Z., Shi, G."Preoperative diagnosis and staging of rectal cancer using diffusion‑weighted and water imaging combined with dynamic contrast‑enhanced scanning". Oncology Letters 8, no. 6 (2014): 2734-2740. https://doi.org/10.3892/ol.2014.2590
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