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Print ISSN: 1792-1074 Online ISSN: 1792-1082
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January-2015 Volume 9 Issue 1

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International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

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Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

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Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

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Case Report Open Access

Complications in the treatment of oropharyngeal carcinoma in patients with systemic sclerosis: A case report

  • Authors:
    • Ales Čoček
    • Ales Hahn
    • Miloslav Ambruš
    • Marie Valešová
  • View Affiliations / Copyright

    Affiliations: ENT Clinic, Charles University Third Medical School and Královské Vinohrady Teaching Hospital, 100 34 Prague 10, Czech Republic, Radiotherapy and Oncology Clinic, Charles University Third Medical School and Královské Vinohrady Teaching Hospital, 100 34 Prague 10, Czech Republic, First Internal Medicine Clinic, Charles University Third Medical School and Královské Vinohrady Teaching Hospital, 100 34 Prague 10, Czech Republic
  • Pages: 25-28
    |
    Published online on: October 22, 2014
       https://doi.org/10.3892/ol.2014.2627
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Abstract

Systemic sclerosis is a chronic, progressive disease with an extremely poor prognosis. The incidence of malignant tumors in patients with systemic sclerosis is increased when compared with that of the general population. In certain malignancies, systemic sclerosis presents as a paraneoplastic process. The symptoms of sclerosis in the organs of the head and neck often overlap with symptoms of malignant diseases, which may increase the difficulty of a differential diagnosis. Additionally, the presence of sclerosis may complicate standard examination procedures, due to poor access to the oral cavity and oropharynx. When considering treatment options, it is important to evaluate the surgical and oncological risks to soft tissues of the head and neck with regard to both diseases, as well as the relatively poor prognosis for systemic sclerosis and oropharyngeal cancer. The low incidence of patients with systemic sclerosis and oropharyngeal carcinoma together presents a clear case for a casuistic approach. Based upon our own experience, we can attest to the difficulty of treating such patients. However, we have no evidence to indicate that these patients have reduced tolerance to surgical treatments. The current study presents the case of a 47‑year‑old female with systemic sclerosis, who was diagnosed with oropharyngeal carcinoma. The patient initially tolerated radiotherapy treatment well, however post‑radiotherapy complications occurred. Despite many enigmatic indications to the contrary, it appears that the complications in this instance may be due to late toxicity from radiotherapy.
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1 

Kuo CF, Luo SF, Yu KH, Chou IJ, Tseng WY, Chang HC, Fang YF, Chiou MJ and See LC: Cancer risk among patients with systemic sclerosis: a nationwide population study in Taiwan. Scand J Rheumatol. 41:44–49. 2012. View Article : Google Scholar

2 

Kang KY, Yim HW, Kim IJ, Yoon JU, Ju JH, Kim HY and Park SH: Incidence of cancer among patients with systemic sclerosis in Korea: results from a single centre. Scand J Rheumatol. 38:299–303. 2009. View Article : Google Scholar : PubMed/NCBI

3 

Siau K, Laversuch Cj, Creamer P and O’Rourke KP: Malignancy in scleroderma patients from south west England: a population-based cohort study. Rheumatol Int. 31:641–645. 2011. View Article : Google Scholar

4 

Szekanecs E, Szamosi S, Horvath A, Nemeth A, Juhasz B, Szanto J, Szücs G and Szekanecz Z: Malignancies associated with systemic sclerosis. Autoimmun Rev. 11:852–855. 2012. View Article : Google Scholar

5 

Derk CT, Rasheed M, Artlett CM and Jimenez SA: A cohort study of cancer incidence in systemic sclerosis. J Rheumatol. 33:1113–1116. 2006.PubMed/NCBI

6 

Derk CT, Rasheed M, Spiegel JR and Jimenez SA: Increased incidence of carcinoma of the tongue in patients with systemic sclerosis. J Rheumatol. 32:637–641. 2005.PubMed/NCBI

7 

Sobin LH, Gospodarowicz MK and Wittekind Ch; International Union Against Cancer (UICC). TNM Classification of Malignant Tumours. 7th edition. Wiley-Blackwell; New York, NY: 2009

8 

Clements PJ and Furst DE: Systemic Sclerosis. 1st edition. Williams & Wilkins; Baltimore, MD: 1996

9 

Kumar P, Galarraga B and Belch JJF: Connective tissues disorders. Rheumatology. Hochberg MC, Silman AJ, Smolen JS, Weinblatt ME and Weisman MH: 5th edition. Mosby Elsevier; Philadelphia, PA: pp. 1361–1437. 2011

10 

Wigley FM: Systemic sclerosis (scleroderma) is unique among our rheumatic diseases. Preface. Rheum Dis Clin North Am. 34:xi–xiiii. 2008. View Article : Google Scholar : PubMed/NCBI

11 

Štork J: Sklerodermie. 1st edition. Galén; Prague: 1996

12 

LeRoy EC, Black CM, Fleischmajer R, et al: Scleroderma (systemic sclerosis): clasification, subsets and pathogenesis. J Rheumatol. 15:202–205. 1988.PubMed/NCBI

13 

Orphanos G, Ardavanis A, Charalambous P, Stavrakakis J and Rigatos G: Systemic sclerosis associated with rectal cancer. Case report and a brief review of the literature. In vivo. 22:825–830. 2008.

14 

Szabolcsi O, Nagy-Toldi A, Zeher M and Vegh J: Systemic sclerosis in a patient suffering from breast cancer. Magy Onkol. 56:50–54. 2012.PubMed/NCBI

15 

Marasini B, Conciato L, Belloli L and Massarotti M: Systemic sclerosis and cancer. Int J Immunopathol Pharmacol. 22:573–578. 2009.PubMed/NCBI

16 

Dragun AE, Harper JL, Olyejar SE, Zunzunegui RG and Wazer DE: The use of adjutant high-dose-rate breast brychytherapy in patients with collagen vascular dinase: a collaborative experience. Brachytherapy. 10:121–127. 2011. View Article : Google Scholar

17 

Kounalakis N, Pezner R, Staud CL and Kruper L: Partial breast irradiation in a patient with bilateral breast cancers and CREST syndrome. Brachytherapy. 10:486–490. 2011. View Article : Google Scholar : PubMed/NCBI

18 

Lowell D, Tatter S, Bourland JD, deGuzman AF, Ekstrand KF, Ellis TL, Lovato JF, McMullen K, Munley MJ, Shaw EG, et al: Toxicity of gamma knife radiosurgery in the treatment of intracranial tumors in patients with collagen vascular diseases or multiple sclerosis. Int J Radiat Oncol Biol Phys. 81:e519–e524. 2011. View Article : Google Scholar : PubMed/NCBI

19 

Lin A, Abu-Isa E, Griffith KA and Ben-Josef E: Toxicity of radiotherapy in patients with collagen vascular disease. Cancer. 113:648–653. 2008. View Article : Google Scholar : PubMed/NCBI

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Copy and paste a formatted citation
Spandidos Publications style
Čoček A, Hahn A, Ambruš M and Valešová M: Complications in the treatment of oropharyngeal carcinoma in patients with systemic sclerosis: A case report. Oncol Lett 9: 25-28, 2015.
APA
Čoček, A., Hahn, A., Ambruš, M., & Valešová, M. (2015). Complications in the treatment of oropharyngeal carcinoma in patients with systemic sclerosis: A case report. Oncology Letters, 9, 25-28. https://doi.org/10.3892/ol.2014.2627
MLA
Čoček, A., Hahn, A., Ambruš, M., Valešová, M."Complications in the treatment of oropharyngeal carcinoma in patients with systemic sclerosis: A case report". Oncology Letters 9.1 (2015): 25-28.
Chicago
Čoček, A., Hahn, A., Ambruš, M., Valešová, M."Complications in the treatment of oropharyngeal carcinoma in patients with systemic sclerosis: A case report". Oncology Letters 9, no. 1 (2015): 25-28. https://doi.org/10.3892/ol.2014.2627
Copy and paste a formatted citation
x
Spandidos Publications style
Čoček A, Hahn A, Ambruš M and Valešová M: Complications in the treatment of oropharyngeal carcinoma in patients with systemic sclerosis: A case report. Oncol Lett 9: 25-28, 2015.
APA
Čoček, A., Hahn, A., Ambruš, M., & Valešová, M. (2015). Complications in the treatment of oropharyngeal carcinoma in patients with systemic sclerosis: A case report. Oncology Letters, 9, 25-28. https://doi.org/10.3892/ol.2014.2627
MLA
Čoček, A., Hahn, A., Ambruš, M., Valešová, M."Complications in the treatment of oropharyngeal carcinoma in patients with systemic sclerosis: A case report". Oncology Letters 9.1 (2015): 25-28.
Chicago
Čoček, A., Hahn, A., Ambruš, M., Valešová, M."Complications in the treatment of oropharyngeal carcinoma in patients with systemic sclerosis: A case report". Oncology Letters 9, no. 1 (2015): 25-28. https://doi.org/10.3892/ol.2014.2627
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