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Case Report

Primary ameloblastic carcinoma of the maxilla: A case report and literature review

  • Authors:
    • Narikazu Uzawa
    • Miho Suzuki
    • Chika Miura
    • Nobuyoshi Tomomatsu
    • Toshiyuki Izumo
    • Kiyoshi Harada
  • View Affiliations / Copyright

    Affiliations: Maxillofacial Surgery, Department of Maxillofacial Reconstruction and Function, Division of Maxillofacial and Neck Reconstruction, Graduate School, Tokyo Medical and Dental University, Tokyo 113‑8549, Japan, Diagnostic Oral Pathology, Division of Oral Health Science, Graduate School, Tokyo Medical and Dental University, Tokyo 113‑8549, Japan
  • Pages: 459-467
    |
    Published online on: October 31, 2014
       https://doi.org/10.3892/ol.2014.2654
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Abstract

Ameloblastic carcinoma (AC) is a rare malignant odontogenic neoplasm that tends to occur in the mandible rather than in the maxilla. This malignancy is classified as a tumor that combines the morphological features of ameloblastoma and carcinoma, regardless of the presence or absence of metastasis. In addition, AC has been classified into two types, primary and secondary. The former develops de novo and the latter develops by malignant transformation of a pre‑existing benign ameloblastoma. The present study describes the case of a 22‑year‑old patient with primary AC of the maxilla. A review of the literature focusing on the clinical details, treatment results and histopathological and phenotypic information available for ameloblastic carcinoma of the maxilla from a 60‑year period was also performed. As a result, it was found that primary AC is dominant in the maxilla and does not exhibit an aggressive phenotype compared with secondary AC. In addition, the presence of recurrence was found to correlate with mortality, indicating that early, aggressive and complete removal of the tumor is the best treatment for survival.
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1 

Angiero F, Borloni R, Macchi M and Stefani M: Ameloblastic carcinoma of the maxillary sinus. Anticancer Res. 28:3847–3854. 2008.

2 

Yoon HJ, Hong SP, Lee JI, et al: Ameloblastic carcinoma: an analysis of 6 cases with review of the literature. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 108:904–913. 2009. View Article : Google Scholar : PubMed/NCBI

3 

Barnes L, Eveson JW, Reichart P and Sidransky D: Odontogenic carcinomas. World Health Organization Classification of Tumours. Pathology and Genetics of Head and Neck Tumours. IARC Press; Lyon: pp. 287–293. 2005

4 

Corio RL, Goldblatt LI, Edwards PA and Hartman KS: Ameloblastic carcinoma: a clinicopathologic study and assessment of eight cases. Oral Surg Oral Med Oral Pathol. 64:570–576. 1987. View Article : Google Scholar : PubMed/NCBI

5 

Benlyazid A, Lacroix-Triki M, Aziza R, et al: Ameloblastic carcinoma of the maxilla: case report and review of the literature. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 104:e17–e24. 2007. View Article : Google Scholar : PubMed/NCBI

6 

Naik V and Kale AD: Ameloblastic carcinoma: a case report. Quintessence Int. 38:873–879. 2007.

7 

Goldenberg D, Sciubba J, Koch W and Tufano RP: Malignant odontogenic tumors: a 22-year experience. Laryngoscope. 114:1770–1774. 2004. View Article : Google Scholar : PubMed/NCBI

8 

Grimes OF and Stephens HB: Adamantinoma of the maxilla metastatic to the lung: case report. Ann Surg. 128:999–1005. 1948. View Article : Google Scholar : PubMed/NCBI

9 

Eda S, Koike H, Tachikawa T, et al: An autopsy case of the malignant ameloblastoma with metastases to the submaxillary lymph nodes, lungs and thoracic vertebrae. Bull Tokyo Dent Coll. 13:91–101. 1972.PubMed/NCBI

10 

Krempien B, Brandeies WE and Singer R: Ameloblastoma with metastases in a child. Light- and electron microscopic findings. Virchows Arch A Path Anat Histol. 381:211–222. 1979.(In German). View Article : Google Scholar

11 

Daramola JO, Abioye AA, Ajagbe HA and Aghadiuno PU: Maxillary malignant ameloblastoma with intraorbital extension: report of case. J Oral Surg. 38:203–206. 1980.PubMed/NCBI

12 

Madiedo G, Choi H and Kleinman JG: Ameloblastoma of the maxilla with distant metastases and hypercalcemia. Am J Clin Pathol. 75:585–591. 1981.PubMed/NCBI

13 

Andersen E and Bang G: Ameloblastic carcinoma of the maxilla. A case report. J Maxillofac Surg. 14:338–340. 1986. View Article : Google Scholar : PubMed/NCBI

14 

Nadimi H, Toto PD, Jaffe E and McReynolds HD: Basement membrane defect in ameloblastic carcinoma: a case study. J Oral Med. 41:79–81. 1986.PubMed/NCBI

15 

Inoue N, Shimojyo M, Iwai H, et al: Malignant ameloblastoma with pulmonary metastasis and hypercalcemia: report of an autopsy case and review of the literature. Am J Clin Pathol. 90:474–481. 1988.PubMed/NCBI

16 

McClatchey KD, Sullivan MJ and Paugh DR: Peripheral ameloblastic carcinoma: a case report of a rare neoplasm. J Otolaryngol. 18:109–111. 1989.PubMed/NCBI

17 

Lee L, Maxymiw WG and Wood RE: Ameloblastic carcinoma of the maxilla metastatic to the mandible. Case report. J Craniomaxillofac Surg. 18:247–250. 1990. View Article : Google Scholar : PubMed/NCBI

18 

Lolachi CM, Madan SK and Jacobs JR: Ameloblastic carcinoima of the maxilla. J Laryngol Otol. 109:1019–1022. 1995. View Article : Google Scholar : PubMed/NCBI

19 

Ingram EA, Evans ML and Zitsch RP III: Fine-needle aspiration cytology of ameloblastic carcinoma of the maxilla: a rare tumor. Diagn Cytopathol. 14:249–252. 1996. View Article : Google Scholar : PubMed/NCBI

20 

Infante-Cossio P, Hernandes-Guisado JM, Fernandez-Machin P, et al: Ameloblastic carcinoma of the maxilla: a report of 3 cases. J Craniomaxillofac Surg. 26:159–162. 1998. View Article : Google Scholar : PubMed/NCBI

21 

Sastre J, Muñoz M, Naval L and Adrados M: Ameloblastic carcinoma of the maxilla: report of a case. J Oral Maxillofac Surg. 60:102–104. 2002. View Article : Google Scholar : PubMed/NCBI

22 

Dhir K, Sciubba J and Tufano RP: Ameloblastic carcinoma of the maxilla. Oral Oncol. 39:736–741. 2003. View Article : Google Scholar : PubMed/NCBI

23 

Avon SL, McComb J and Clokie C: Ameloblastic carcinoma: case report and literature review. J Can Dent Assoc. 69:573–576. 2003.PubMed/NCBI

24 

Oginni FO, Ugboko VI, Owotade JF and Adebiyi KE: Ameloblastic carcinoma of the jaws. A report of three Nigerian cases. Odontostomatol Trop. 104:19–22. 2003.

25 

Zwablen RA, Vogt P, Fiscber FS and Grätz KW: Case report: myocardical metastasis of a maxillary ameloblastoma. J Oral Maxillofac Surg. 61:731–734. 2003. View Article : Google Scholar

26 

Philip M, Morris CG, Werning JW and Mendenhall WM: Radiotherapy in the treatment of ameloblastoma and ameloblastic carcinoma. J HK Coll Radiol. 8:157–161. 2005.

27 

Hall JM, Weathers DR and Unni KK: Ameloblastic carcinoma: an analysis of 14 cases. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 103:799–807. 2007. View Article : Google Scholar : PubMed/NCBI

28 

Ward BB, Edlund S, Sciubba J and Helman JI: Ameloblastic carcinoma (primary type) isolated to the anterior maxilla: case report with review of the literature. J Oral Maxillafac Surg. 65:1800–1803. 2007. View Article : Google Scholar

29 

Yazici N, Karagöz B, Varan A, et al: Maxillary ameloblastic carcinoma in a child. Pediatr Blood Cancer. 50:175–176. 2008. View Article : Google Scholar

30 

Lucca M, D’Innocenzo R, Kraus JA, et al: Ameloblastic carcinoma of the maxilla: a report of 2 cases. J Oral Maxillofac Surg. 68:2564–2569. 2010. View Article : Google Scholar : PubMed/NCBI

31 

Matsuzaki H, Katase N, Hara M, et al: Ameloblastic carcinoma: a case report with radiological features of computed tomography and magnetic resonance imaging and positron emission tomography. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 112:e40–e47. 2011. View Article : Google Scholar : PubMed/NCBI

32 

Nicolotti M, Brucoli M, Arcuri F and Benech A: Ameloblastic carcinoma: rare localization of a rare neoplasm. J Craniofac Surg. 22:2353–2355. 2011. View Article : Google Scholar : PubMed/NCBI

33 

França DC, Moreira JM Jr, De Aguiar SM, et al: Ameloblastic carcinoma of the maxilla: A case report. Oncol Lett. 4:1297–1300. 2012.PubMed/NCBI

34 

Kramer IRH, Pindborg JJ and Torloni H: International Histological Classification of Tumours. Histological Typing of Odontogenic Tumors, Jaw, Cyst and Allied Lesions. World Health Organization; Geneva: 1971

35 

Elzay RP: Primary intraosseous carcinoma of the jaws. Review and update of odontogenic carcinomas. Oral Surg Oral Med Oral Pathol. 54:299–303. 1982. View Article : Google Scholar : PubMed/NCBI

36 

Slootweg PJ and Müller H: Malignant ameloblastoma or ameloblastic carcinoma. Oral Surg Oral Med Oral Pathol. 57:168–176. 1984. View Article : Google Scholar : PubMed/NCBI

37 

Lanham RJ: Chemotherapy of metastatic ameloblastoma. A case report and review of the literature. Oncology. 44:133–134. 1987. View Article : Google Scholar : PubMed/NCBI

38 

Duffey DC, Bailet JW and Newman A: Ameloblastoma of the mandible with cervical lymph node metastasis. Am J Otolaryngol. 16:66–73. 1995. View Article : Google Scholar : PubMed/NCBI

39 

Ramadas K, Jose CC, Subhashini J, et al: Pulmonary metastases from ameloblastoma of the mandible treated with cisplatin, adriamycin, and cyclophosphamide. Cancer. 66:1475–1479. 1990. View Article : Google Scholar : PubMed/NCBI

40 

Casaroto AR, Toledo GL, Filho JL, et al: Ameloblastic carcinoma, primary type: case report, immunohistochemical analysis and literature review. Anticancer Res. 32:1515–1525. 2012.PubMed/NCBI

41 

Zwahlen RA and Grätz KW: Maxillary ameloblastomas: a review of the literature and of a 15-year database. J Craniomaxillofac Surgery. 30:273–279. 2002. View Article : Google Scholar

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Copy and paste a formatted citation
Spandidos Publications style
Uzawa N, Suzuki M, Miura C, Tomomatsu N, Izumo T and Harada K: Primary ameloblastic carcinoma of the maxilla: A case report and literature review. Oncol Lett 9: 459-467, 2015.
APA
Uzawa, N., Suzuki, M., Miura, C., Tomomatsu, N., Izumo, T., & Harada, K. (2015). Primary ameloblastic carcinoma of the maxilla: A case report and literature review. Oncology Letters, 9, 459-467. https://doi.org/10.3892/ol.2014.2654
MLA
Uzawa, N., Suzuki, M., Miura, C., Tomomatsu, N., Izumo, T., Harada, K."Primary ameloblastic carcinoma of the maxilla: A case report and literature review". Oncology Letters 9.1 (2015): 459-467.
Chicago
Uzawa, N., Suzuki, M., Miura, C., Tomomatsu, N., Izumo, T., Harada, K."Primary ameloblastic carcinoma of the maxilla: A case report and literature review". Oncology Letters 9, no. 1 (2015): 459-467. https://doi.org/10.3892/ol.2014.2654
Copy and paste a formatted citation
x
Spandidos Publications style
Uzawa N, Suzuki M, Miura C, Tomomatsu N, Izumo T and Harada K: Primary ameloblastic carcinoma of the maxilla: A case report and literature review. Oncol Lett 9: 459-467, 2015.
APA
Uzawa, N., Suzuki, M., Miura, C., Tomomatsu, N., Izumo, T., & Harada, K. (2015). Primary ameloblastic carcinoma of the maxilla: A case report and literature review. Oncology Letters, 9, 459-467. https://doi.org/10.3892/ol.2014.2654
MLA
Uzawa, N., Suzuki, M., Miura, C., Tomomatsu, N., Izumo, T., Harada, K."Primary ameloblastic carcinoma of the maxilla: A case report and literature review". Oncology Letters 9.1 (2015): 459-467.
Chicago
Uzawa, N., Suzuki, M., Miura, C., Tomomatsu, N., Izumo, T., Harada, K."Primary ameloblastic carcinoma of the maxilla: A case report and literature review". Oncology Letters 9, no. 1 (2015): 459-467. https://doi.org/10.3892/ol.2014.2654
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