Nasopharyngeal carcinoma metastasis to the mammary gland: A case report
- Authors:
View Affiliations
Affiliations: Department of Oncology, The First People's Hospital of Jingzhou, Jingzhou, Hubei 434000, P.R. China
- Published online on: November 3, 2014 https://doi.org/10.3892/ol.2014.2656
-
Pages:
275-277
Metrics: Total
Views: 0 (Spandidos Publications: | PMC Statistics: )
Metrics: Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )
This article is mentioned in:
Abstract
Nasopharyngeal carcinoma is the second most common type of malignancy in Southern China. Metastatic sites are usually multifocal and involve the bones, lungs and distant lymph nodes. To date, there have been no studies with regard to nasopharyngeal carcinoma metastasis to the mammary gland. In the current study, the case of a 56‑year‑old female with nasal obstruction, epitaxis and a bilateral neck mass is presented. Following a series of examinations, the patient was diagnosed with nasopharyngeal carcinoma (cT3N3M0). Subsequently, the patient received radical radiation therapy. After three months, a mass was identified in the left breast, together with enlargement of multiple lymph nodes in the left axilla. The patient underwent a mastectomy and pathological examination revealed that the breast mass and axillary lymph node tissues were derived from the nasopharynx. To the best of our knowledge, this is the first report of a nasopharyngeal carcinoma that metastasized to the mammary gland.
View References
1
|
Wei KR, Zheng RS, Zhang SW, et al:
Nasopharyngeal carcinoma incidence and mortality in China in 2010.
Chin J Cancer. 33:381–387. 2014.PubMed/NCBI
|
2
|
Lee AW, Poon YF, Foo W, et al:
Retrospective analysis of 5037 patients with nasopharyngeal
carcinoma treated during 1976–1985: overall survival and pattern of
failure. Int J Radiat Oncol Biol Phys. 23:261–270. 1992. View Article : Google Scholar
|
3
|
Barnes L, Eveson JW, Reichart P and
Sidransky D: Pathology and Genetics of Head and Neck Tumors. World
Health Organization Classification of Tumors. IARC Press; Lyon: pp.
91–111. 2005
|
4
|
Edge S, Byrd D, Compton C, et al: AJCC
Cancer Staging Manual. 7th edition. Springer; New York, NY:
2010
|
5
|
Abrams HL, Spiro R and Goldstein N:
Metastases in carcinoma: analysis of 1000 autopsied cases. Cancer.
3:74–85. 1950. View Article : Google Scholar : PubMed/NCBI
|
6
|
Sandison AT: Metastatic tumors in the
breast. Br J Surg. 47:54–58. 1959. View Article : Google Scholar : PubMed/NCBI
|
7
|
Hajdu SI and Urban JA: Cancers metastatic
to the breast. Cancer. 29:1691–1696. 1972. View Article : Google Scholar : PubMed/NCBI
|
8
|
Vergier B, Trojani M, de Mascarel I,
Coindre JM and Le Treut A: Metastases to the breast: differential
diagnosis from primary breast carcinoma. J Surg Oncol. 48:112–116.
1991. View Article : Google Scholar : PubMed/NCBI
|
9
|
Klingen TA, Klaasen H, Aas H, Chen Y and
Akslen LA: Secondary breast cancer: a 5-year population-based study
with review of the literature. APMIS. 117:762–767. 2009. View Article : Google Scholar : PubMed/NCBI
|
10
|
Shuling Li: Head and neck oncology.
Scientific and Technological Literature Publishing House; Beijing:
pp. 522–542. 2002
|
11
|
Leung SF, Teo PM, Shiu WW, et al: Clinical
features and management of distant metastases of nasopharyngeal
carcinoma. J Otoralyngol. 20:27–29. 1991.
|
12
|
Fandi A, Bachouchi M, Azli N, et al:
Long-term disease-free survivors in metastatic undifferentiated
carcinoma of nasopharyngeal type. J Clin Oncol. 18:1324–1330.
2000.PubMed/NCBI
|