Subcutaneous nephrovesical bypass: Treatment for ureteral obstruction in advanced metastatic disease

Wang,Yunyan; Wang,Gongcheng; Hou,Peijin; Zhuang,Haijun; Yang,Xiaosong; Gu,Shuo; Wang,Hengbing; Ji,Lu; Xu,Zongyuan; Meng,Junsong

doi:10.3892/ol.2014.2679

January-2015 Volume 9 Issue 1

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January-2015 Volume 9 Issue 1

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Article

Subcutaneous nephrovesical bypass: Treatment for ureteral obstruction in advanced metastatic disease

Authors:
- Yunyan Wang
- Gongcheng Wang
- Peijin Hou
- Haijun Zhuang
- Xiaosong Yang
- Shuo Gu
- Hengbing Wang
- Lu Ji
- Zongyuan Xu
- Junsong Meng
View Affiliations / Copyright

Affiliations: Department of Urology, Huai'an First People's Hospital, Nanjing Medical University, Huai'an, Jiangsu 223300, P.R. China
Pages: 387-390
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Published online on: November 6, 2014

https://doi.org/10.3892/ol.2014.2679
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Abstract

The aim of the present study was to explore the value of subcutaneous nephrovesical bypass (SNVB) for the treatment of ureteral obstruction due to pelvic metastatic disease. SNVB stents (n=30) were implanted in 24 patients with advanced metastatic disease between January 2008 and December 2012. Urinalysis, serum creatinine (SCr), glomerular filtration rate (GFR), quality of life (QoL) scores, and renal ultrasonography were evaluated at follow‑up. The SNVB procedures were successful in all 24 patients. Patient follow‑ups occurred at an average of 10.6 months. Preoperative hydronephrosis was eliminated in 16 cases (53.3%) and reduced in the remaining patients. Following surgery, SCr levels reduced significantly from 256±46 to 124±23 µmol/l (P<0.001). GFRs increased from 25±4.8 to 45±5.3 ml/min (P<0.01). The mean QoL scores were 3.4±1.4 preoperatively and 7.6±1.0 postoperatively (P<0.001). The results showed that SNVB is a minimally invasive, effective and safe procedure for patients with ureteral obstruction resulting from advanced malignant disease. As an alternative procedure to percutaneous nephrostomy, SNVB offers patients a better QoL.

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Journals

International Journal of Molecular Medicine

International Journal of Oncology

Molecular Medicine Reports

Oncology Reports

Experimental and Therapeutic Medicine

Oncology Letters

Biomedical Reports

Molecular and Clinical Oncology

World Academy of Sciences Journal

International Journal of Functional Nutrition

International Journal of Epigenetics

Medicine International

Subcutaneous nephrovesical bypass: Treatment for ureteral obstruction in advanced metastatic disease

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Abstract

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