Synchronous occurrence of gastrointestinal stromal tumor and intrahepatic cholangiocarcinoma: A case report

Nam,Seung‑Joo; Choi,Hyuk  Soon; Kim,Eun  Sun; Keum,Bora; Jeen,Yoon  Tae; Chun,Hoon  Jai

doi:10.3892/ol.2014.2703

January-2015 Volume 9 Issue 1

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January-2015 Volume 9 Issue 1

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Case Report

Synchronous occurrence of gastrointestinal stromal tumor and intrahepatic cholangiocarcinoma: A case report

Authors:
- Seung‑Joo Nam
- Hyuk Soon Choi
- Eun Sun Kim
- Bora Keum
- Yoon Tae Jeen
- Hoon Jai Chun
View Affiliations / Copyright

Affiliations: Division of Gastroenterology and Hepatology, Department of Internal Medicine, Korea University College of Medicine, Seoul 136‑705, Republic of Korea
Pages: 165-168
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Published online on: November 12, 2014

https://doi.org/10.3892/ol.2014.2703
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Abstract

Various cases of gastrointestinal stromal tumor (GIST) coinciding with other gastrointestinal malignancies have been reported to date, however, the synchronous occurrence of GIST and intrahepatic cholangiocarcinoma (ICC) is exceptionally rare and, to the best of our knowledge, has only been reported once. The coinciding malignancy has usually been encountered incidentally during surgical exploration. Thus, this is the first report where a targeted biopsy of the clinically suspicious lesion was used to determine the diagnosis of ICC concurrent with GIST. The liver is the most frequent metastatic site of GIST, therefore, additional hepatic masses may be mistakenly diagnosed as metastatic disease, rather than the presentation of multiple primary tumors. This subsequently delays the accurate diagnosis and complicates the performance of a curable resection. The current study reports a case of advanced synchronous GIST and ICC, which was operable at initial presentation, but progressed to become surgically unresectable.

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Journals

International Journal of Molecular Medicine

International Journal of Oncology

Molecular Medicine Reports

Oncology Reports

Experimental and Therapeutic Medicine

Oncology Letters

Biomedical Reports

Molecular and Clinical Oncology

World Academy of Sciences Journal

International Journal of Functional Nutrition

International Journal of Epigenetics

Medicine International

Synchronous occurrence of gastrointestinal stromal tumor and intrahepatic cholangiocarcinoma: A case report

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Abstract

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