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Case Report Open Access

Follicular dendritic cell sarcoma of the right tonsil: A case report and literature review

  • Authors:
    • Zhong‑Jie Lu
    • Ji Li
    • Shui‑Hong Zhou
    • Li‑Bo Dai
    • Sen‑Xiang Yan
    • Ting‑Ting Wu
    • Yang‑Yang Bao
  • View Affiliations / Copyright

    Affiliations: Department of Radiotherapy, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, Zhejiang 310003, P.R. China, Department of Otolaryngology, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, Zhejiang 310003, P.R. China
    Copyright: © Lu et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Pages: 575-582
    |
    Published online on: November 21, 2014
       https://doi.org/10.3892/ol.2014.2726
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Abstract

The current study presents a case of extranodal follicular dendritic cell sarcoma (FDCS) of the tonsil and reviews the relevant literature. In the present case, a 59‑year‑old male presented with a globus sensation in the right pharynx for 6 weeks. On clinical examination, a painless non-ulcerated enlarged right tonsil was identified; the tonsil was covered with a normal mucus membrane. A right tonsillectomy was performed under general anesthesia. The final pathological diagnosis was follicular dendritic cell sarcoma of the right tonsil.Postoperatively, the patient received radiotherapy. The patient remains alive without disease recurrence or metastasis 44 months after tonsillectomy. To the best of our knowledge, only 42 cases of FDCS of the tonsil have been reported to date. Of the 42 cases, 41 patients underwent surgery and one patient refused treatment. A total of 23 (54.7%) received surgery alone. Adjuvant treatment was administered for 18 patients (42.9%). Six patients (14.3%) experienced local recurrences and two patients (4.8%) succumbed to the disease 24 months after treatment. The three‑, five‑, and eight‑year overall survival rates for the entire group were 86.5, 77.8 and 77.8%, respectively. Furthermore, a tumor diameter of ≥4 cm was prognostic upon univariate analysis (χ2=4.634; P=0.031; excluding incomplete data). Tonsillar FDCS is rare and is associated with high rates of recurrence and metastasis, therefore, adjuvant treatment should be prescribed.
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1 

Karligkiotis A, Contis D, Bella M, et al: Pediatric follicular dendritic cell sarcoma of the head and neck: a case report and review of the literature. Int J Pediatr Otorhinolaryngol. 77:1059–1064. 2013. View Article : Google Scholar : PubMed/NCBI

2 

Hu T, Wang X, Yu C, et al: Follicular dendritic cell sarcoma of the pharyngeal region. Oncol Lett. 5:1467–1476. 2013.PubMed/NCBI

3 

Monda L, Warnke R and Rosai J: A primary lymph node malignancy with features suggestive of dendritic reticulum cell differentiation. A report of 4 cases. Am J Pathol. 122:562–572. 1986.PubMed/NCBI

4 

De Pas T, Spitaleri G, Pruneri G, et al: Dendritic cell sarcoma: an analytic overview of the literature and presentation of original five cases. Crit Rev Oncol Hematol. 65:1–7. 2008. View Article : Google Scholar

5 

Kara T, Serinsoz E, Arpaci RB and Vayisoglu Y: Follicular dendritic cell sarcoma of the tonsil. BMJ Case Rep. 2013.bcr20120074402013.PubMed/NCBI

6 

Mondal SK, Bera H, Bhattacharya B and Dewan K: Follicular dendritic cell sarcoma of the tonsil. Natl J Maxillofac Surg. 3:62–64. 2012. View Article : Google Scholar : PubMed/NCBI

7 

Eun YG, Kim SW and Kwon KH: Follicular dendritic cell sarcoma of the tonsil. Yonsei Med J. 51:602–604. 2010. View Article : Google Scholar : PubMed/NCBI

8 

Suhail Z, Musani MA, Afaq S, et al: Follicular dendritic cell sarcoma of tonsil. J Coll Physicians Surg Pak. 20:55–56. 2010.PubMed/NCBI

9 

Duan GJ, Wu F, Zhu J, et al: Extranodal follicular dendritic cell sarcoma of the pharyngeal region: a potential diagnostic pitfall, with literature review. Am J Clin Pathol. 133:49–58. 2010. View Article : Google Scholar

10 

Li L, Shi YH, Guo ZJ, et al: Clinicopathological features and prognosis assessment of extranodal follicular dendritic cell sarcoma. World J Gastroenterol. 16:2504–2519. 2010. View Article : Google Scholar : PubMed/NCBI

11 

Vaideeswar P, George SM, Kane SV, Chaturvedi RA and Pandit SP: Extranodal follicular dendritic cell sarcoma of the tonsil-case report of an epithelioid cell variant with osteoclastic giant cells. Pathol Res Pract. 205:149–153. 2009. View Article : Google Scholar

12 

McDuffie C, Lian TS and Thibodeaux J: Follicular dendritic cell sarcoma of the tonsil: a case report and literature review. Ear Nose Throat J. 86:234–235. 2007.PubMed/NCBI

13 

Fan YS, Ng WK, Chan A, et al: Fine needle aspiration cytology in follicular dendritic cell sarcoma: a report of two cases. Acta Cytol. 51:642–647. 2007. View Article : Google Scholar : PubMed/NCBI

14 

Aydin E, Ozluoglu LN, Demirhan B and Arikan U: Follicular dendritic cell sarcoma of the tonsil: case report. Eur Arch Otorhinolaryngol. 263:1155–1157. 2006. View Article : Google Scholar : PubMed/NCBI

15 

Clement P, Saint-Blancard P, Minvielle F, Le Page P and Kossowski M: Follicular dendritic cell sarcoma of the tonsil: a case report. Am J Otolaryngol. 27:207–210. 2006. View Article : Google Scholar : PubMed/NCBI

16 

Shia J, Chen W, Tang LH, et al: Extranodal follicular dendritic cell sarcoma: clinical, pathologic, and histogenetic characteristics of an underrecognized disease entity. Virchows Arch. 449:148–158. 2006. View Article : Google Scholar : PubMed/NCBI

17 

Bothra R, Pai PS, Chaturvedi P, et al: Follicular dendritic cell tumour of tonsil-is it an under-diagnosed entity? Indian J Cancer. 42:211–214. 2005.

18 

Domínguez-Malagón H, Cano-Valdez AM, Mosqueda-Taylor A and Hes O: Follicular dendritic cell sarcoma of the pharyngeal region: histologic, cytologic, immunohistochemical, and ultrastructural study of three cases. Ann Diagn Pathol. 8:325–332. 2004. View Article : Google Scholar : PubMed/NCBI

19 

Idrees MT, Brandwein-Gensler M, Strauchen JA, et al: Extranodal follicular dendritic cell tumor of the tonsil: report of a diagnostic pitfall and literature review. Arch Otolaryngol Head Neck Surg. 130:1109–1113. 2004. View Article : Google Scholar : PubMed/NCBI

20 

Grogg KL, Lae ME, Kurtin PJ and Macon WR: Clusterin expression distinguishes follicular dendritic cell tumors from other dendritic cell neoplasms: report of a novel follicular dendritic cell marker and clinicopathologic data on 12 additional follicular dendritic cell tumors and 6 additional interdigitating dendritic cell tumors. Am J Surg Pathol. 28:988–998. 2004. View Article : Google Scholar : PubMed/NCBI

21 

Tisch M, Hengstermann F, Kraft K, von Hinüber G and Maier H: Follicular dendritic cell sarcoma of the tonsil: report of a rare case. Ear Nose Throat J. 82:507–509. 2003.PubMed/NCBI

22 

Biddle DA, Ro JY, Yoon GS, et al: Extranodal follicular dendritic cell sarcoma of the head and neck region: three new cases, with a review of the literature. Mod Pathol. 15:50–58. 2002. View Article : Google Scholar : PubMed/NCBI

23 

Vargas H, Mouzakes J, Purdy SS, et al: Follicular dendritic cell tumor: an aggressive head and neck tumor. Am J Otolaryngol. 23:93–98. 2002. View Article : Google Scholar : PubMed/NCBI

24 

Chan JK, Fletcher CD, Nayler SJ and Cooper K: Follicular dendritic cell sarcoma: Clinicopathologic analysis of 17 cases suggesting a malignant potential higher than previously recognized. Cancer. 9:294–313. 1997. View Article : Google Scholar

25 

Nayler SJ, Verhaart MJ and Cooper K: Follicular dendritic cell tumour of the tonsil. Histopathology. 28:89–92. 1996. View Article : Google Scholar : PubMed/NCBI

26 

Perez-Ordonez B, Erlandson RA and Rosai J: Follicular dendritic cell tumor: report of 13 additional cases of a distinctive entity. Am J Surg Pathol. 20:944–955. 1996. View Article : Google Scholar : PubMed/NCBI

27 

Chan JK, Tsang WY, Ng CS, et al: Follicular dendritic cell tumors of the oral cavity. Am J Surg Pathol. 18:148–157. 1994. View Article : Google Scholar : PubMed/NCBI

28 

Shi QL, Zhou XJ, Ma J, et al: Follicular dendritic cell sarcoma of tonsil: a case report and review of the literature. Zhen Duan Bing Li Xue Za Zhi. 11:81–83. 2004.(In Chinese).

29 

Zhang ZX, Cheng J, Shi QL, et al: Follicular dendritic cell sarcoma a clinicopathologic study of 8 cases. Zhong Hua Bing Xue Za Zhi. 37:395–399. 2008.(In Chinese).

30 

Chen YP, Chen G, Lin J, et al: Clinicopathologic analysis of four cases of extranodal follicular dentritic cell sarcoma. Bai Xue Bing Lin Ba Liu. 18:619–621. 2009.(In Chinese).

31 

Chen YH, Luo KS, Jian Y, Luo Y and Fan YY: Follicular dendritic cell sarcoma: A clinicopathologic study of 4 cases. Zhong Guo Zhong Liu Lin Chuang. 36:901–904. 2009.(In Chinese).

32 

Ma SR, Li KC, Xu YQ, et al: Follicular dentritic cell sarcoma: a clinicopathologic analysis of 6 cases. Lin Chuang Yu Shi Yan Bing Li Xue Za Zhi. 26:565–568. 2010.(In Chinese).

33 

Yin WH, Yu GY, Ma Y, et al: Follicular dendritic cell sarcoma a clinicopathologic analysis of ten cases. Zhong Hua Bing Xue Za Zhi. 39:522–527. 2010.(In Chinese).

34 

Liu BA, Wang HW, Zhao L, Chen H, Liu LJ and Su ZS: Follicular dendritic cell sarcoma a clinicopathologic analysis of five cases. Zhen Duan Bing Li Xue Za Zhi. 17:182–185. 1892010.(In Chinese).

35 

Yang LH, Zhang AH, Wang WF, Wang FC and Chen FY: Follicular dendritic cell sarcoma of tonsil: a case report. Zhong Guo Shi Yan Zhen Duan Xue. 15:1215–1216. 2011.(In Chinese).

36 

Wang Q, An LF, Cui N, Sha JC and Zhu DD: Follicular dendritic cell sarcoma: a case report and review of literature. Lin Chuang Er Bi Yan Hou Ke Za Zhi. 25:100–102. 2011.(In Chinese).

37 

Zhang LJ, Li M and Chen Y: Follicular dendritic cell sarcoma of tonsil: a case report. Shi Yong Yi Xue Za Zhi. 28:28042012.(In Chinese).

38 

Wu HB, Chen K, Hu W and Wang XQ: Epithelioid follicular dentritic cell sarcoma of the tonsil: case report and review of the literature. Xian Dui Zhong Liu Yi Xue. 20:1581–1584. 2012.(In Chinese).

39 

Leipsic JA, McAdams HP and Sporn TA: Follicular dendritic cell sarcoma of the mediastinum. AJR Am J Roentgenol. 188:554–556. 2007. View Article : Google Scholar

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Copy and paste a formatted citation
Spandidos Publications style
Lu ZJ, Li J, Zhou SH, Dai LB, Yan SX, Wu TT and Bao YY: Follicular dendritic cell sarcoma of the right tonsil: A case report and literature review. Oncol Lett 9: 575-582, 2015.
APA
Lu, Z., Li, J., Zhou, S., Dai, L., Yan, S., Wu, T., & Bao, Y. (2015). Follicular dendritic cell sarcoma of the right tonsil: A case report and literature review. Oncology Letters, 9, 575-582. https://doi.org/10.3892/ol.2014.2726
MLA
Lu, Z., Li, J., Zhou, S., Dai, L., Yan, S., Wu, T., Bao, Y."Follicular dendritic cell sarcoma of the right tonsil: A case report and literature review". Oncology Letters 9.2 (2015): 575-582.
Chicago
Lu, Z., Li, J., Zhou, S., Dai, L., Yan, S., Wu, T., Bao, Y."Follicular dendritic cell sarcoma of the right tonsil: A case report and literature review". Oncology Letters 9, no. 2 (2015): 575-582. https://doi.org/10.3892/ol.2014.2726
Copy and paste a formatted citation
x
Spandidos Publications style
Lu ZJ, Li J, Zhou SH, Dai LB, Yan SX, Wu TT and Bao YY: Follicular dendritic cell sarcoma of the right tonsil: A case report and literature review. Oncol Lett 9: 575-582, 2015.
APA
Lu, Z., Li, J., Zhou, S., Dai, L., Yan, S., Wu, T., & Bao, Y. (2015). Follicular dendritic cell sarcoma of the right tonsil: A case report and literature review. Oncology Letters, 9, 575-582. https://doi.org/10.3892/ol.2014.2726
MLA
Lu, Z., Li, J., Zhou, S., Dai, L., Yan, S., Wu, T., Bao, Y."Follicular dendritic cell sarcoma of the right tonsil: A case report and literature review". Oncology Letters 9.2 (2015): 575-582.
Chicago
Lu, Z., Li, J., Zhou, S., Dai, L., Yan, S., Wu, T., Bao, Y."Follicular dendritic cell sarcoma of the right tonsil: A case report and literature review". Oncology Letters 9, no. 2 (2015): 575-582. https://doi.org/10.3892/ol.2014.2726
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