|
1
|
Bertuccio P, Chatenoud L, Levi F, Praud D,
Ferlay J, Negri E, Malvezzi M and La Vecchia C: Recent patterns in
gastric cancer: a global overview. Int J Cancer. 125:666–673. 2009.
View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Leung WK, Wu MS, Kakugawa Y, Kim JJ, Yeoh
KG, Goh KL, Wu KC, Wu DC, Sollano J, Kachintorn U, et al; Asia
Pacific Working Group of Gastric Cancer. Screening for gastric
cancer in Asia: current evidence and practice. Lancet Oncol.
9:279–287. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Crew KD and Neugut AI: Epidemiology of
gastric cancer. World J Gastroenterol. 12:354–362. 2006.PubMed/NCBI
|
|
4
|
Macdonald JS: Gastric cancer - new
therapeutic options. N Engl J Med. 355:76–77. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Cunningham D and Chua YJ: East meets west
in the treatment of gastric cancer. N Engl J Med. 357:1863–1865.
2007. View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Ngo SN, Williams DB and Head RJ: Rosemary
and cancer prevention: preclinical perspectives. Crit Rev Food Sci
Nutr. 51:946–954. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Shishodia S, Majumdar S, Banerjee S and
Aggarwal BB: Ursolic acid inhibits nuclear factor-κB activation
induced by carcinogenic agents through suppression of IκBα kinase
and p65 phosphorylation: correlation with down-regulation of
cyclooxygenase 2, matrix metalloproteinase 9, and cyclin D1. Cancer
Res. 63:4375–4383. 2003.PubMed/NCBI
|
|
8
|
Wang X, Zhang F, Yang L, Mei Y, Long H,
Zhang X, Zhang J, Qimuge-Suyila and Su X: Ursolic acid inhibits
proliferation and induces apoptosis of cancer cells in vitro and in
vivo. J Biomed Biotechnol. 2011:4193432011. View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Lin CC, Huang CY, Mong MC, Chan CY and Yin
MC: Antiangiogenic potential of three triterpenic acids in human
liver cancer cells. J Agric Food Chem. 59:755–762. 2011. View Article : Google Scholar
|
|
10
|
Huang CY, Lin CY, Tsai CW and Yin MC:
Inhibition of cell proliferation, invasion and migration by ursolic
acid in human lung cancer cell lines. Toxicol In Vitro.
25:1274–1280. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Li Y, Xing D, Chen Q and Chen WR:
Enhancement of chemotherapeutic agent-induced apoptosis by
inhibition of NF-κB using ursolic acid. Int J Cancer. 127:462–473.
2010.
|
|
12
|
Ma CM, Cai SQ, Cui JR, Wang RQ, Tu PF,
Hattori M, Hattori M and Daneshtalab M: The cytotoxic activity of
ursolic acid derivatives. Eur J Med Chem. 40:582–589. 2005.
View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Shanmugam MK, Manu KA, Ong TH,
Ramachandran L, Surana R, Bist P, Lim LH, Kumar AP, Hui KM and
Sethi G: Inhibition of CXCR4/CXCL12 signaling axis by ursolic acid
leads to suppression of metastasis in transgenic adenocarcinoma of
mouse prostate model. Int J Cancer. 129:1552–1563. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
14
|
De Angel RE, Smith SM, Glickman RD,
Perkins SN and Hursting SD: Antitumor effects of ursolic acid in a
mouse model of postmenopausal breast cancer. Nutr Cancer.
62:1074–1086. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Prasad S, Yadav VR, Sung B, Reuter S,
Kannappan R, Deorukhkar A, Diagaradjane P, Wei C,
Baladandayuthapani V, Krishnan S, et al: Ursolic acid inhibits
growth and metastasis of human colorectal cancer in an orthotopic
nude mouse model by targeting multiple cell signaling pathways:
chemosensitization with capecitabine. Clin Cancer Res.
18:4942–4953. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Yeh CT, Wu CH and Yen GC: Ursolic acid, a
naturally occurring triterpenoid, suppresses migration and invasion
of human breast cancer cells by modulating c-Jun N-terminal kinase,
Akt and mammalian target of rapamycin signaling. Mol Nutr Food Res.
54:1285–1295. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Yu LB, Wang J, Ma BZ and Sun WZ:
Inhibitive effect of ursolic acid on the invasion and metastasis of
ovarian carcinoma cells HO-8910PM. Sichuan Da Xue Xue Bao Yi Xue
Ban. 41:986–988. 2010.(In Chinese).
|
|
18
|
Hanahan D and Weinberg RA: Hallmarks of
cancer: the next generation. Cell. 144:646–674. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Steller-Stevenson WG: Type IV collagenases
in tumor invasion and metastasis. Cancer Metastasis Rev. 9:289–303.
1990. View Article : Google Scholar
|
|
20
|
Stetler-Stevenson WG, Liotta LA and
Kleiner DE Jr: Extracellular matrix 6: role of matrix
metalloproteinases in tumor invasion and metastasis. FASEB J.
7:1434–1441. 1993.PubMed/NCBI
|
|
21
|
Chiarugi V, Magnelli L, Cinelli M and Basi
G: Apoptosis and the cell cycle. Cell Mol Biol Res. 40:603–612.
1994.PubMed/NCBI
|
|
22
|
Fernald K and Kurokawa M: Evading
apoptosis in cancer. Trends Cell Biol. 23:620–633. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Kroemer G: The proto-oncogene Bcl-2 and
its role in regulating apoptosis. Nat Med. 3:614–620. 1997.
View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Ashkenazi A and Dixit VM: Death receptors:
signaling and modulation. Science. 281:1305–1308. 1998. View Article : Google Scholar : PubMed/NCBI
|
|
25
|
Blanc C, Deveraux QL, Krajewski S, Jänicke
RU, Porter AG, Reed JC, Jaggi R and Marti A: Caspase-3 is essential
for procaspase-9 processing and cisplatin-induced apoptosis of
MCF-7 breast cancer cells. Cancer Res. 60:4386–4390.
2000.PubMed/NCBI
|
|
26
|
Seger R and Krebs EG: The MAPK signaling
cascade. FASEB J. 9:726–735. 1995.PubMed/NCBI
|
|
27
|
Westwick JK, Bielawska AE, Dbaibo G,
Hannun YA and Brenner DA: Ceramide activates the stress-activated
protein kinases. J Biol Chem. 270:22689–22692. 1995. View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Tibbles LA and Woodgett JR: The
stress-activated protein kinase pathways. Cell Mol Life Sci.
55:1230–1254. 1999. View Article : Google Scholar : PubMed/NCBI
|
|
29
|
Davis RJ: Signal transduction by the JNK
group of MAP kinases. Cell. 103:239–252. 2000. View Article : Google Scholar : PubMed/NCBI
|
|
30
|
Yu R, Shtil AA, Tan TH, Roninson IB and
Kong AN: Adriamycin activates c-jun N-terminal kinase in human
leukemia cells: a relevance to apoptosis. Cancer Lett. 107:73–81.
1996. View Article : Google Scholar : PubMed/NCBI
|
|
31
|
Chen YR, Meyer CF and Tan TH: Persistent
activation of c-Jun N-terminal kinase 1 (JNK1) in gamma
radiation-induced apoptosis. J Biol Chem. 271:631–634. 1996.
View Article : Google Scholar : PubMed/NCBI
|
|
32
|
Cagnol S and Chambard JC: ERK and cell
death: mechanisms of ERK-induced cell death - apoptosis, autophagy
and senescence. FEBS J. 277:2–21. 2010. View Article : Google Scholar
|
|
33
|
Germain M, Affar EB, D’Amours D, Dixit VM,
Salvesen GS and Poirier GG: Cleavage of automodified
poly(ADP-ribose) polymerase during apoptosis. Evidence for
involvement of caspase-7. J Biol Chem. 274:28379–28384. 1999.
View Article : Google Scholar : PubMed/NCBI
|
|
34
|
Karikas GA: Anticancer and chemopreventing
natural products: some biochemical and therapeutic aspects. J BUON.
15:627–638. 2010.
|
|
35
|
Ou Y, Li Q, Wang J, Li K and Zhou S:
Antitumor and apoptosis induction effects of paeonol on mice
bearing EMT6 breast carcinoma. Biomol Ther (Seoul). 22:341–346.
2014. View Article : Google Scholar
|
|
36
|
Li Y, Lu X, Qi H, Li X, Xiao X and Gao J:
Ursolic acid induces apoptosis through mitochondrial intrinsic
pathway and suppression of ERK1/2 MAPK in HeLa cells. J Pharmacol
Sci. 125:202–210. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
37
|
Kim KH, Seo HS, Choi HS, Choi I, Shin YC
and Ko SG: Induction of apoptotic cell death by ursolic acid
through mitochondrial death pathway and extrinsic death receptor
pathway in MDA-MB-231 cells. Arch Pharm Res. 34:1363–1372. 2011.
View Article : Google Scholar : PubMed/NCBI
|
|
38
|
Wada T and Penninger JM: Mitogen-activated
protein kinases in apoptosis regulation. Oncogene. 23:2838–2849.
2004. View Article : Google Scholar : PubMed/NCBI
|
|
39
|
Raingeaud J, Gupta S, Rogers JS, Dickens
M, Han J, Ulevitch RJ and Davis RJ: Pro-inflammatory cytokines and
environmental stress cause p38 mitogen-activated protein kinase
activation by dual phosphorylation on tyrosine and threonine. J
Biol Chem. 270:7420–7426. 1995. View Article : Google Scholar : PubMed/NCBI
|
|
40
|
Sarkar D, Su ZZ, Lebedeva IV, Sauane M,
Gopalkrishnan RV, Valerie K, Dent P and Fisher PB: Mda-7 (IL-24)
mediates selective apoptosis in human melanoma cells by inducing
the coordinated overexpression of the GADD family of genes by means
of p38 MAPK. Proc Natl Acad Sci USA. 99:10054–10059. 2002.
View Article : Google Scholar : PubMed/NCBI
|
|
41
|
Porras A, Zuluaga S, Black E, Valladares
A, Alvarez AM, Ambrosino C, Benito M and Nebreda AR: P38α
mitogen-activated protein kinase sensitizes cells to apoptosis
induced by different stimuli. Mol Biol Cell. 15:922–933. 2004.
View Article : Google Scholar :
|
|
42
|
Yosimichi G, Nakanishi T, Nishida T,
Hattori T, Takano-Yamamoto T and Takigawa M: CTGF/Hcs24 induces
chondrocyte differentiation through a p38 mitogen-activated protein
kinase (p38MAPK), and proliferation through a p44/42
MAPK/extracellular-signal regulated kinase (ERK). Eur J Biochem.
268:6058–6065. 2001. View Article : Google Scholar : PubMed/NCBI
|
|
43
|
Park JM, Greten FR, Li ZW and Karin M:
Macrophage apoptosis by anthrax lethal factor through p38 MAP
kinase inhibition. Science. 297:2048–2051. 2002. View Article : Google Scholar : PubMed/NCBI
|
|
44
|
Gong YY, Liu YY, Yu S, Zhu XN, Cao XP and
Xiao HP: Ursolic acid suppresses growth and adrenocorticotrophic
hormone secretion in AtT20 cells as a potential agent targeting
adrenocorticotrophic hormone-producing pituitary adenoma. Mol Med
Rep. 9:2533–2539. 2014.PubMed/NCBI
|
|
45
|
Liu XS and Jiang J: Induction of apoptosis
and regulation of the MAPK pathway by ursolic acid in human
leukemia K562 cells. Planta Med. 73:1192–1194. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
46
|
Zhang YX, Kong CZ, Wang HQ, Wang LH, Xu CL
and Sun YH: Phosphorylation of Bcl-2 and activation of caspase-3
via the c-Jun N-terminal kinase pathway in ursolic acid-induced
DU145 cells apoptosis. Biochimie. 91:1173–1179. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
47
|
Lynch CC and Matrisian LM: Matrix
metalloproteinases in tumor-host cell communication.
Differentiation. 70:561–573. 2002. View Article : Google Scholar : PubMed/NCBI
|
|
48
|
Liotta LA, Tryggvason K, Garbisa S, Hart
I, Foltz CM and Shafie S: Metastatic potential correlates with
enzymatic degradation of basement-membrane collagen. Nature.
284:67–68. 1980. View
Article : Google Scholar : PubMed/NCBI
|
|
49
|
Lee YD, Cui MN, Yoon HH, Kim HY, Oh IH and
Lee JH: Down-modulation of Bis reduces the invasive ability of
glioma cells induced by TPA, through NF-κB mediated activation of
MMP-9. BMB Rep. 47:262–267. 2014. View Article : Google Scholar :
|
|
50
|
Ham M and Moon A: Inflammatory and
microenvironmental factors involved in breast cancer progression.
Arch Pharm Res. 36:1419–1431. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
51
|
Yong HY and Moon A: Roles of
calcium-binding proteins, S100A8 and S100A9, in invasive phenotype
of human gastric cancer cells. Arch Pharm Res. 30:75–81. 2007.
View Article : Google Scholar : PubMed/NCBI
|
|
52
|
Tsuchiya A, Kikuchi Y, Ando Y, Yoshida T
and Abe R: Lymph node metastases in gastric cancer invading the
submucosal layer. Eur J Surg Oncol. 21:248–250. 1995. View Article : Google Scholar : PubMed/NCBI
|
