Gastric metastasis from sphenoid sinus melanoma: A case report

Zhao,Lianjun; Yan,Jing; Li,Li; Wei,Jia; Li,Lin; Qian,Xiaoping; Liu,Baorui; Zou,Zhengyun

doi:10.3892/ol.2014.2745

February-2015 Volume 9 Issue 2

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February-2015 Volume 9 Issue 2

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Case Report Open Access

Gastric metastasis from sphenoid sinus melanoma: A case report

Authors:
- Lianjun Zhao
- Jing Yan
- Li Li
- Jia Wei
- Lin Li
- Xiaoping Qian
- Baorui Liu
- Zhengyun Zou
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Affiliations: Comprehensive Cancer Center of Nanjing Drum Tower Hospital, Clinical College of Nanjing Medical University, Nanjing, Jiangsu 210008, P.R. China, Comprehensive Cancer Center of Nanjing Drum Tower Hospital, Medical School and Clinical Cancer Institute of Nanjing University, Nanjing, Jiangsu 210008, P.R. China

Copyright: © Zhao et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
Pages: 609-613
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Published online on: November 28, 2014

https://doi.org/10.3892/ol.2014.2745
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Abstract

Clinical reports of primary sphenoid sinus melanoma and isolated gastric metastatic melanoma are rare. Thus, to the best of our knowledge, the present study reports the first case of isolated gastric metastasis from a sphenoid sinus melanoma. The aim of the present study was to discuss the clinicopathological and radiographic characteristics, the treatment strategy and the prognosis of sphenoid sinus metastatic malignant melanoma of the stomach. Although almost 60% of patients who succumb to melanoma exhibit gastrointestinal metastases at autopsy, antemortem diagnosis is uncommon; this is predominantly due to gastric metastatic melanoma presenting with non‑specific symptoms similar to other common gastrointestinal diseases. Gastrectomy may prolong overall survival and improve the quality of life for gastric metastatic melanoma patients, and the present case emphasizes the importance of palliative surgery in such cases.

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1	Markovic SN, Erickson LA, Rao RD, et al; Melanoma Study Group of the Mayo Clinic Cancer Center. Malignant melanoma in the 21st century, part 1: epidemiology, risk factors, screening, prevention, and diagnosis. Mayo Clin Proc. 82:364–380. 2007. View Article : Google Scholar : PubMed/NCBI
2	Thompson JF, Scolyer RA and Kefford RF: Cutaneous melanoma. Lancet. 365:687–701. 2005. View Article : Google Scholar : PubMed/NCBI
3	Markovic SN, Erickson LA, Rao RD, et al; Melanoma Study Group of the Mayo Clinic Cancer Center. Malignant melanoma in the 21st century, part 2: staging, prognosis, and treatment. Mayo Clin Proc. 82:490–513. 2007. View Article : Google Scholar : PubMed/NCBI
4	Carter TR: Pathologic quiz case 1. Malignant melanoma. Arch Otolaryngol Head Neck Surg. 112:450–453. 1986.PubMed/NCBI
5	Shinbori T, Uyama E, Eto K, Kohrogi H and Araki S: An autopsy case of malignant melanoma possibly originating in the sphenoid sinus. Rinsho Shinkeigaku. 28:636–642. 1988.(In Japanese). PubMed/NCBI
6	Asano K, Sobata E, Yamazaki K and Kubo O: Malignant melanoma arising from the sphenoidal sinus - case report. Neurol Med Chir (Tokyo). 40:329–334. 2000. View Article : Google Scholar
7	Busaba NY: Primary melanoma of the sphenoid sinus. Otolaryngol Head Neck Surg. 123:748–749. 2000. View Article : Google Scholar : PubMed/NCBI
8	Pino Rivero V, Keituqwa Yánez T, Marcos García M, et al: Melanoma of sphenoid sinus. Case presentation and review of literature. Acta Otorrinolaringol Esp. 55:45–48. 2004.(In Spanish). View Article : Google Scholar : PubMed/NCBI
9	Lynch SC, Lee AG, Graham SM and Kirby PA: Primary melanoma of the sphenoid sinus presenting with a third cranial nerve palsy. J Neuroophthalmol. 25:289–292. 2005. View Article : Google Scholar : PubMed/NCBI
10	Tsukahara K, Nakamura K, Motohashi R, Endo M and Sato H: A case report of malignant melanoma of the sphenoid sinus. Case Rep Otolaryngol. 2013:6134722013.PubMed/NCBI
11	Batra K, Chhabra A, Rampure J, et al: CT and MRI appearances of primary sphenoid melanoma: a rare case. AJNR Am J Neuroradiol. 26:2642–2644. 2005.PubMed/NCBI
12	Eisenhauer EA, Therasse P, Bogaerts J, et al: New response evaluation criteria in solid tumours: revised RECIST guideline (version 1.1). Eur J Cancer. 45:228–247. 2009. View Article : Google Scholar
13	Chi Z, Li S, Sheng X, et al: Clinical presentation, histology, and prognoses of malignant melanoma in ethnic Chinese: a study of 522 consecutive cases. BMC Cancer. 11:852011. View Article : Google Scholar : PubMed/NCBI
14	Osguthorpe JD: Sinus neoplasia. Arch Otolaryngol Head Neck Surg. 120:19–25. 1994. View Article : Google Scholar : PubMed/NCBI
15	Harbo G, Grau C, Bundgaard T, et al: Cancer of the nasal cavity and paranasal sinuses. A clinico-pathological study of 277 patients. Acta Oncol. 36:45–50. 1997. View Article : Google Scholar : PubMed/NCBI
16	Blecker D, Abraham S, Furth EE and Kochman ML: Melanoma in the gastrointestinal tract. Am J Gastroenterol. 94:3427–3433. 1999. View Article : Google Scholar : PubMed/NCBI
17	Patel JK, Didolkar MS, Pickren JW and Moore RH: Metastatic pattern of malignant melanoma. A study of 216 autopsy cases. Am J Surg. 135:807–810. 1978. View Article : Google Scholar : PubMed/NCBI
18	Stukavec J and Horák L: The malignant melanoma metastasis into the stomach corpus. Rozhl Chir. 84:148–150. 2005.(In Czech). PubMed/NCBI
19	Cohen VM, Ahmadi-Iari S and Hungerford JL: Gastric metastases from conjunctival melanoma. Melanoma Res. 17:255–256. 2007. View Article : Google Scholar : PubMed/NCBI
20	Naumann SC, Roos WP, Jöst E, et al: Temozolomide- and fotemustine-induced apoptosis in human malignant melanoma cells: response related to MGMT, MMR, DSBs, and p53. Br J Cancer. 100:322–333. 2009. View Article : Google Scholar : PubMed/NCBI
21	Ollila DW, Essner R, Wanek LA and Morton DL: Surgical resection for melanoma metastatic to the gastrointestinal tract. Arch Surg. 131:975–979. 979–980. 1996. View Article : Google Scholar : PubMed/NCBI

Journals

International Journal of Molecular Medicine

International Journal of Oncology

Molecular Medicine Reports

Oncology Reports

Experimental and Therapeutic Medicine

Oncology Letters

Biomedical Reports

Molecular and Clinical Oncology

World Academy of Sciences Journal

International Journal of Functional Nutrition

International Journal of Epigenetics

Medicine International

Gastric metastasis from sphenoid sinus melanoma: A case report

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Abstract

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