Primary malignant melanoma of the trachea: A case report

Imai,Hisao; Kiyohara,Yoshio; Yoshikawa,Shusuke; Kusutani,Nao; Ono,Akira; Taira,Tetsuhiko; Kenmotsu,Hirotsugu; Harada,Hideyuki; Naito,Tateaki; Murakami,Haruyasu; Sano,Takehisa; Fuji,Hiroshi; Endo,Masahiro; Nakajima,Takashi; Takahashi,Toshiaki

doi:10.3892/ol.2014.2782

February-2015 Volume 9 Issue 2

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February-2015 Volume 9 Issue 2

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Case Report

Primary malignant melanoma of the trachea: A case report

Authors:
- Hisao Imai
- Yoshio Kiyohara
- Shusuke Yoshikawa
- Nao Kusutani
- Akira Ono
- Tetsuhiko Taira
- Hirotsugu Kenmotsu
- Hideyuki Harada
- Tateaki Naito
- Haruyasu Murakami
- Takehisa Sano
- Hiroshi Fuji
- Masahiro Endo
- Takashi Nakajima
- Toshiaki Takahashi
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Affiliations: Division of Thoracic Oncology, Shizuoka Cancer Center, Suntou‑gun, Shizuoka 411-8777, Japan, Division of Dermatology, Shizuoka Cancer Center, Suntou‑gun, Shizuoka 411-8777, Japan, Division of Radiation Oncology, Shizuoka Cancer Center, Suntou‑gun, Shizuoka 411-8777, Japan, Department of Respiratory Medicine, Shizuoka City Hospital, Aoi‑ku, Shizuoka 420-8630, Japan, Division of Proton Therapy, Shizuoka Cancer Center, Suntou‑gun, Shizuoka 411-8777, Japan, Division of Diagnostic Radiology, Shizuoka Cancer Center, Suntou‑gun, Shizuoka 411-8777, Japan, Division of Diagnostic Pathology, Shizuoka Cancer Center, Suntou‑gun, Shizuoka 411-8777, Japan
Pages: 657-660
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Published online on: December 9, 2014

https://doi.org/10.3892/ol.2014.2782
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Abstract

Primary cancer of the trachea is rare and accounts for only 0.1‑0.4% of all newly diagnosed respiratory tract cancers, worldwide. In the present study, a case of primary tracheal malignant melanoma, a particularly rare type of cancer, is reported. A 68‑year‑old male presented with a cough and bloody sputum. A chest computed tomography scan revealed a 25x20x15‑mm tracheal tumor, located immediately above the carina, which reduced the cross‑sectional area of the trachea by ~90%. Histopathological analysis of biopsy specimens determined a diagnosis of malignant melanoma. The patient was treated with argon plasma coagulation and chemoradiotherapy, which restored airway patency, however, metastasis was detected in the lungs. The patient refused further treatment and received palliative care. Subsequently, the patient succumbed to the disease within four months. Thus, although primary malignant melanoma of the trachea is extremeley rare, the possibility should be considered during diagnosis.

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Journals

International Journal of Molecular Medicine

International Journal of Oncology

Molecular Medicine Reports

Oncology Reports

Experimental and Therapeutic Medicine

Oncology Letters

Biomedical Reports

Molecular and Clinical Oncology

World Academy of Sciences Journal

International Journal of Functional Nutrition

International Journal of Epigenetics

Medicine International

Primary malignant melanoma of the trachea: A case report

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