Primary laryngeal manifestation in precursor T-cell acute lymphoblastic leukemia

Wang,Lin; Ma,Yan; Chen,Bobin; Tang,Feng; Xu,Xiaoping; Lin,Guowei

doi:10.3892/ol.2014.2800

February-2015 Volume 9 Issue 2

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February-2015 Volume 9 Issue 2

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Article

Primary laryngeal manifestation in precursor T-cell acute lymphoblastic leukemia

Authors:
- Lin Wang
- Yan Ma
- Bobin Chen
- Feng Tang
- Xiaoping Xu
- Guowei Lin
View Affiliations / Copyright

Affiliations: Department of Hematology, Huashan Hospital, Fudan University, Shanghai 200040, P.R. China, Department of Pathology, Huashan Hospital, Fudan University, Shanghai 200040, P.R. China
Pages: 691-694
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Published online on: December 12, 2014

https://doi.org/10.3892/ol.2014.2800
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Abstract

Primary involvement of the larynx in non‑Hodgkin's lymphoma (NHL) is rare. Early symptoms are non‑specific and thus, it is difficult to diagnose. In the present study, the case of a 52 year‑old male with hoarseness due to diffuse T‑cell lymphoma as the first manifestation of precursor T‑cell acute lymphoblastic leukemia is presented. Subsequent to treatment with three cycles of the etoposide and cytosine arabinoside (EA) and one cycle of the EA+L‑asp chemotherapy regimens, the patient achieved complete remission. A series of consolidation therapy courses were performed subsequently. At present, the patient remains disease‑free, indicating that the treatment was effective. Primary involvement of the larynx in NHL is rare. Symptoms in the early stage are subtle and non‑specific and thus, diagnosis is difficult to establish. This type of tumor requires special diagnostic and therapeutic attention.

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Journals

International Journal of Molecular Medicine

International Journal of Oncology

Molecular Medicine Reports

Oncology Reports

Experimental and Therapeutic Medicine

Oncology Letters

Biomedical Reports

Molecular and Clinical Oncology

World Academy of Sciences Journal

International Journal of Functional Nutrition

International Journal of Epigenetics

Medicine International

Primary laryngeal manifestation in precursor T-cell acute lymphoblastic leukemia

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Abstract

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