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Article

Clinicopathological features of invasive micropapillary carcinoma of the breast

  • Authors:
    • Zhao‑Qing Cui
    • Ji‑Huan Feng
    • Yi‑Jun Zhao
  • View Affiliations / Copyright

    Affiliations: Department of Breast and Thyroid Surgery, Liaocheng People's Hospital of Shandong Province, Liaocheng, Shandong 252000, P.R. China
  • Pages: 1163-1166
    |
    Published online on: December 17, 2014
       https://doi.org/10.3892/ol.2014.2806
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Abstract

The aim of the present study was to evaluate the clinical and immunohistopathological findings of invasive micropapillary carcinoma (IMPC) of the breast. In total, 25 patients were included in the present study, all of whom were diagnosed with IMPC. The mammography and ultrasound scanning (US) findings were analysed retrospectively according to the American College of Radiology Breast Imaging Reporting and Data System lexicon. Surgical specimens obtained from the patients were microscopically reviewed in consensus by two pathologists with a specialisation in breast pathology. All the patients presented with palpable lumps in the breast, a high‑density irregular mass associated with microcalcifications revealed by mammography and an irregular hypoechoic mass with a spiculated margin revealed by US. Axillary lymph node metastases were identified in 80% of the patients. Immunohistochemical studies revealed the lesions to be highly positive for the oestrogen receptor (ER) and c‑erbB‑2 (88% and 84%, respectively). Although no significant imaging characteristics were found to distinguish IMPC from typical invasive ductal carcinoma, IMPC resulted in nodal metastases and was highly positive for ER and c‑erbB‑2. This clinical significance indicates the significance of this entity being recognised by pathologists and surgeons.
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Copy and paste a formatted citation
Spandidos Publications style
Cui ZQ, Feng JH and Zhao YJ: Clinicopathological features of invasive micropapillary carcinoma of the breast. Oncol Lett 9: 1163-1166, 2015.
APA
Cui, Z., Feng, J., & Zhao, Y. (2015). Clinicopathological features of invasive micropapillary carcinoma of the breast. Oncology Letters, 9, 1163-1166. https://doi.org/10.3892/ol.2014.2806
MLA
Cui, Z., Feng, J., Zhao, Y."Clinicopathological features of invasive micropapillary carcinoma of the breast". Oncology Letters 9.3 (2015): 1163-1166.
Chicago
Cui, Z., Feng, J., Zhao, Y."Clinicopathological features of invasive micropapillary carcinoma of the breast". Oncology Letters 9, no. 3 (2015): 1163-1166. https://doi.org/10.3892/ol.2014.2806
Copy and paste a formatted citation
x
Spandidos Publications style
Cui ZQ, Feng JH and Zhao YJ: Clinicopathological features of invasive micropapillary carcinoma of the breast. Oncol Lett 9: 1163-1166, 2015.
APA
Cui, Z., Feng, J., & Zhao, Y. (2015). Clinicopathological features of invasive micropapillary carcinoma of the breast. Oncology Letters, 9, 1163-1166. https://doi.org/10.3892/ol.2014.2806
MLA
Cui, Z., Feng, J., Zhao, Y."Clinicopathological features of invasive micropapillary carcinoma of the breast". Oncology Letters 9.3 (2015): 1163-1166.
Chicago
Cui, Z., Feng, J., Zhao, Y."Clinicopathological features of invasive micropapillary carcinoma of the breast". Oncology Letters 9, no. 3 (2015): 1163-1166. https://doi.org/10.3892/ol.2014.2806
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