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Case Report

Blastic plasmacytoid dendritic cell neoplasm: A case report

  • Authors:
    • Wei Wang
    • Wensheng Li
    • Jin‑Jing Jia
    • Yan Zheng
    • Hao Wang
    • Xiao‑Min Gao
    • Xin‑Yu Dong
    • Qiong Tian
    • Hui‑Ling Jing
    • Xin Wang
    • Sheng‑Xiang Xiao
  • View Affiliations / Copyright

    Affiliations: Department of Dermatology, Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, P.R. China, Department of Pathology, Third Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, P.R. China
  • Pages: 1388-1392
    |
    Published online on: December 29, 2014
       https://doi.org/10.3892/ol.2014.2836
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Abstract

Blastic plasmacytoid dendritic cell neoplasm (BPDCN), formerly known as agranular cluster of differentiation (CD)4+/CD56+ hematodermic neoplasm, is a rare and aggressive type of lymphoma, with only ~100 cases reported worldwide. BPDCN is a hematological malignancy derived from precursors of plasmacytoid dendritic cells and is clinically characterized by cutaneous manifestations involving the lymph nodes and peripheral blood, a leukemia‑like dissemination and a poor prognosis. The present study reports the case of a 54‑year‑old male who presented with symptoms characteristic of BPDCN. Pathological and immunohistochemical analysis of abdominal skin lesion biopsies were used to determine a diagnosis of stage ⅢE BPDCN. Although cyclophosphamide, doxorubicin, vincristine and prednisolone chemotherapy was administered, the patient succumbed to BPDCN nine days after the discontinuation of chemotherapy. Thus, the period from BPDCN presentation to mortality was ≤3 months. The case reported in the present study was characterized by rapid development and poor prognosis, and displayed additional features of BPDCN, including systemic dissemination and a short survival period.
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Copy and paste a formatted citation
Spandidos Publications style
Wang W, Li W, Jia JJ, Zheng Y, Wang H, Gao XM, Dong XY, Tian Q, Jing HL, Wang X, Wang X, et al: Blastic plasmacytoid dendritic cell neoplasm: A case report. Oncol Lett 9: 1388-1392, 2015.
APA
Wang, W., Li, W., Jia, J., Zheng, Y., Wang, H., Gao, X. ... Xiao, S. (2015). Blastic plasmacytoid dendritic cell neoplasm: A case report. Oncology Letters, 9, 1388-1392. https://doi.org/10.3892/ol.2014.2836
MLA
Wang, W., Li, W., Jia, J., Zheng, Y., Wang, H., Gao, X., Dong, X., Tian, Q., Jing, H., Wang, X., Xiao, S."Blastic plasmacytoid dendritic cell neoplasm: A case report". Oncology Letters 9.3 (2015): 1388-1392.
Chicago
Wang, W., Li, W., Jia, J., Zheng, Y., Wang, H., Gao, X., Dong, X., Tian, Q., Jing, H., Wang, X., Xiao, S."Blastic plasmacytoid dendritic cell neoplasm: A case report". Oncology Letters 9, no. 3 (2015): 1388-1392. https://doi.org/10.3892/ol.2014.2836
Copy and paste a formatted citation
x
Spandidos Publications style
Wang W, Li W, Jia JJ, Zheng Y, Wang H, Gao XM, Dong XY, Tian Q, Jing HL, Wang X, Wang X, et al: Blastic plasmacytoid dendritic cell neoplasm: A case report. Oncol Lett 9: 1388-1392, 2015.
APA
Wang, W., Li, W., Jia, J., Zheng, Y., Wang, H., Gao, X. ... Xiao, S. (2015). Blastic plasmacytoid dendritic cell neoplasm: A case report. Oncology Letters, 9, 1388-1392. https://doi.org/10.3892/ol.2014.2836
MLA
Wang, W., Li, W., Jia, J., Zheng, Y., Wang, H., Gao, X., Dong, X., Tian, Q., Jing, H., Wang, X., Xiao, S."Blastic plasmacytoid dendritic cell neoplasm: A case report". Oncology Letters 9.3 (2015): 1388-1392.
Chicago
Wang, W., Li, W., Jia, J., Zheng, Y., Wang, H., Gao, X., Dong, X., Tian, Q., Jing, H., Wang, X., Xiao, S."Blastic plasmacytoid dendritic cell neoplasm: A case report". Oncology Letters 9, no. 3 (2015): 1388-1392. https://doi.org/10.3892/ol.2014.2836
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