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Review

Involvement of long non-coding RNA in colorectal cancer: From benchtop to bedside (Review)

  • Authors:
    • Le‑Chi Ye
    • De‑Xiang Zhu
    • Jun‑Jun Qiu
    • Jianmin Xu
    • Ye Wei
  • View Affiliations / Copyright

    Affiliations: Department of Oncological Surgery, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, P.R. China, Department of General Surgery, Zhongshan Hospital, Fudan University, Shanghai, P.R. China, Department of Gynecology, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, P.R. China
  • Pages: 1039-1045
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    Published online on: January 5, 2015
       https://doi.org/10.3892/ol.2015.2846
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Abstract

Colorectal cancer (CRC) is one of the greatest threats to public health. Recent advances in whole‑genome transcriptome analyses have enabled the identification of numerous members of a novel class of non‑coding (nc)RNA, long ncRNA (lncRNA), which is broadly defined as RNA molecules that are >200 nt in length and lacking an open reading frame. In the present review, all lncRNAs associated with CRC are briefly summarized, with a particular focus on their potential roles as clinical biomarkers. CRC‑associated lncRNAs involved in the underlying mechanisms of CRC progression are also initially included. This should benefit the development of novel markers and effective therapeutic targets for patients with CRC.
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Copy and paste a formatted citation
Spandidos Publications style
Ye LC, Zhu DX, Qiu JJ, Xu J and Wei Y: Involvement of long non-coding RNA in colorectal cancer: From benchtop to bedside (Review). Oncol Lett 9: 1039-1045, 2015.
APA
Ye, L., Zhu, D., Qiu, J., Xu, J., & Wei, Y. (2015). Involvement of long non-coding RNA in colorectal cancer: From benchtop to bedside (Review). Oncology Letters, 9, 1039-1045. https://doi.org/10.3892/ol.2015.2846
MLA
Ye, L., Zhu, D., Qiu, J., Xu, J., Wei, Y."Involvement of long non-coding RNA in colorectal cancer: From benchtop to bedside (Review)". Oncology Letters 9.3 (2015): 1039-1045.
Chicago
Ye, L., Zhu, D., Qiu, J., Xu, J., Wei, Y."Involvement of long non-coding RNA in colorectal cancer: From benchtop to bedside (Review)". Oncology Letters 9, no. 3 (2015): 1039-1045. https://doi.org/10.3892/ol.2015.2846
Copy and paste a formatted citation
x
Spandidos Publications style
Ye LC, Zhu DX, Qiu JJ, Xu J and Wei Y: Involvement of long non-coding RNA in colorectal cancer: From benchtop to bedside (Review). Oncol Lett 9: 1039-1045, 2015.
APA
Ye, L., Zhu, D., Qiu, J., Xu, J., & Wei, Y. (2015). Involvement of long non-coding RNA in colorectal cancer: From benchtop to bedside (Review). Oncology Letters, 9, 1039-1045. https://doi.org/10.3892/ol.2015.2846
MLA
Ye, L., Zhu, D., Qiu, J., Xu, J., Wei, Y."Involvement of long non-coding RNA in colorectal cancer: From benchtop to bedside (Review)". Oncology Letters 9.3 (2015): 1039-1045.
Chicago
Ye, L., Zhu, D., Qiu, J., Xu, J., Wei, Y."Involvement of long non-coding RNA in colorectal cancer: From benchtop to bedside (Review)". Oncology Letters 9, no. 3 (2015): 1039-1045. https://doi.org/10.3892/ol.2015.2846
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