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Print ISSN: 1792-1074 Online ISSN: 1792-1082
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March-2015 Volume 9 Issue 3

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International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

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Case Report

Partial remission of acute myeloid leukemia complicating multiple myeloma following COAP chemotherapy: A case report

  • Authors:
    • Man Shen
    • Wan‑Jun Sun
    • Zhong‑Xia Huang
    • Jia‑Jia Zhang
    • Na An
    • Xin Li
  • View Affiliations / Copyright

    Affiliations: Department of Hematology and Oncology, Beijing Chaoyang Hospital, Capital Medical University, Beijing 100043, P.R. China, Department of Hematology, The Second Artillery General Hospital, Beijing 100088, P.R. China
  • Pages: 1303-1306
    |
    Published online on: January 12, 2015
       https://doi.org/10.3892/ol.2015.2867
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Abstract

A 77‑year‑old male was admitted to hospital after complaining of fever and a cough for three days. A diagnosis of multiple myeloma was confirmed following M protein identification and a bone marrow biopsy. The patient received chemotherapy regimens of bortezomib plus dexamethasone, cyclophosphamide, thalidomide and dexamethasone, and thalidomide and dexamethasone, and was prescribed thalidomide (100 mg/d) to be taken orally for maintenance therapy. After a further two years the patient was subsequently diagnosed with acute myeloid leukemia. Chemotherapy regimens of cytarabine, aclacinomycin and daunorubicin, homoharringtonine and etoposide, and mitoxantrone and cytarabine resulted in no remission. Partial remission was obtained with a course of ifosfamide, vindesine, cytarabine and prednisone chemotherapy. This therapy may be an alternative treatment for secondary leukemia, particularly in elderly patients.
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Copy and paste a formatted citation
Spandidos Publications style
Shen M, Sun WJ, Huang ZX, Zhang JJ, An N and Li X: Partial remission of acute myeloid leukemia complicating multiple myeloma following COAP chemotherapy: A case report. Oncol Lett 9: 1303-1306, 2015.
APA
Shen, M., Sun, W., Huang, Z., Zhang, J., An, N., & Li, X. (2015). Partial remission of acute myeloid leukemia complicating multiple myeloma following COAP chemotherapy: A case report. Oncology Letters, 9, 1303-1306. https://doi.org/10.3892/ol.2015.2867
MLA
Shen, M., Sun, W., Huang, Z., Zhang, J., An, N., Li, X."Partial remission of acute myeloid leukemia complicating multiple myeloma following COAP chemotherapy: A case report". Oncology Letters 9.3 (2015): 1303-1306.
Chicago
Shen, M., Sun, W., Huang, Z., Zhang, J., An, N., Li, X."Partial remission of acute myeloid leukemia complicating multiple myeloma following COAP chemotherapy: A case report". Oncology Letters 9, no. 3 (2015): 1303-1306. https://doi.org/10.3892/ol.2015.2867
Copy and paste a formatted citation
x
Spandidos Publications style
Shen M, Sun WJ, Huang ZX, Zhang JJ, An N and Li X: Partial remission of acute myeloid leukemia complicating multiple myeloma following COAP chemotherapy: A case report. Oncol Lett 9: 1303-1306, 2015.
APA
Shen, M., Sun, W., Huang, Z., Zhang, J., An, N., & Li, X. (2015). Partial remission of acute myeloid leukemia complicating multiple myeloma following COAP chemotherapy: A case report. Oncology Letters, 9, 1303-1306. https://doi.org/10.3892/ol.2015.2867
MLA
Shen, M., Sun, W., Huang, Z., Zhang, J., An, N., Li, X."Partial remission of acute myeloid leukemia complicating multiple myeloma following COAP chemotherapy: A case report". Oncology Letters 9.3 (2015): 1303-1306.
Chicago
Shen, M., Sun, W., Huang, Z., Zhang, J., An, N., Li, X."Partial remission of acute myeloid leukemia complicating multiple myeloma following COAP chemotherapy: A case report". Oncology Letters 9, no. 3 (2015): 1303-1306. https://doi.org/10.3892/ol.2015.2867
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