Partial remission of acute myeloid leukemia complicating multiple myeloma following COAP chemotherapy: A case report

  • Authors:
    • Man Shen
    • Wan‑Jun Sun
    • Zhong‑Xia Huang
    • Jia‑Jia Zhang
    • Na An
    • Xin Li
  • View Affiliations

  • Published online on: January 12, 2015     https://doi.org/10.3892/ol.2015.2867
  • Pages: 1303-1306
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Abstract

A 77‑year‑old male was admitted to hospital after complaining of fever and a cough for three days. A diagnosis of multiple myeloma was confirmed following M protein identification and a bone marrow biopsy. The patient received chemotherapy regimens of bortezomib plus dexamethasone, cyclophosphamide, thalidomide and dexamethasone, and thalidomide and dexamethasone, and was prescribed thalidomide (100 mg/d) to be taken orally for maintenance therapy. After a further two years the patient was subsequently diagnosed with acute myeloid leukemia. Chemotherapy regimens of cytarabine, aclacinomycin and daunorubicin, homoharringtonine and etoposide, and mitoxantrone and cytarabine resulted in no remission. Partial remission was obtained with a course of ifosfamide, vindesine, cytarabine and prednisone chemotherapy. This therapy may be an alternative treatment for secondary leukemia, particularly in elderly patients.
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March-2015
Volume 9 Issue 3

Print ISSN: 1792-1074
Online ISSN:1792-1082

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Spandidos Publications style
Shen M, Sun WJ, Huang ZX, Zhang JJ, An N and Li X: Partial remission of acute myeloid leukemia complicating multiple myeloma following COAP chemotherapy: A case report. Oncol Lett 9: 1303-1306, 2015
APA
Shen, M., Sun, W., Huang, Z., Zhang, J., An, N., & Li, X. (2015). Partial remission of acute myeloid leukemia complicating multiple myeloma following COAP chemotherapy: A case report. Oncology Letters, 9, 1303-1306. https://doi.org/10.3892/ol.2015.2867
MLA
Shen, M., Sun, W., Huang, Z., Zhang, J., An, N., Li, X."Partial remission of acute myeloid leukemia complicating multiple myeloma following COAP chemotherapy: A case report". Oncology Letters 9.3 (2015): 1303-1306.
Chicago
Shen, M., Sun, W., Huang, Z., Zhang, J., An, N., Li, X."Partial remission of acute myeloid leukemia complicating multiple myeloma following COAP chemotherapy: A case report". Oncology Letters 9, no. 3 (2015): 1303-1306. https://doi.org/10.3892/ol.2015.2867