Poorly differentiated cecal adenocarcinoma showing prominent rhabdoid feature combined with appendiceal mucinous cystadenoma: A case report and review of the literature

Cho,In‑Ju; Kim,Sung‑Soo; Min,Young‑Don; Noh,Mun-Whan; Hong,Ran

doi:10.3892/ol.2015.2905

April-2015 Volume 9 Issue 4

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April-2015 Volume 9 Issue 4

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Case Report Open Access

Poorly differentiated cecal adenocarcinoma showing prominent rhabdoid feature combined with appendiceal mucinous cystadenoma: A case report and review of the literature

Authors:
- In‑Ju Cho
- Sung‑Soo Kim
- Young‑Don Min
- Mun-Whan Noh
- Ran Hong
View Affiliations / Copyright

Affiliations: Department of Pathology, College of Medicine, Chosun University, Gwangju 501‑759, Republic of Korea, Department of Surgery, College of Medicine, Chosun University, Gwangju 501‑759, Republic of Korea, Department of Complementary and Alternative Medicine, Chosun University Graduate School, Gwangju 501‑759, Republic of Korea

Copyright: © Cho et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
Pages: 1527-1530
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Published online on: January 27, 2015

https://doi.org/10.3892/ol.2015.2905
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Abstract

Extrarenal rhabdoid tumors (ERRTs) are extremely rare neoplasms; of these, colorectal ERRTs are the most rare, and only nine cases have been previously described in the English language literature. The current study reports the pathological features of a case of poorly differentiated cecal adenocarcinoma with prominent rhabdoid feature, which was combined with mucinous cystadenoma of the appendix in a 73‑year‑old male, and additionally reviews the previously reported cases. Microscopically, the majority of tumor cells were non‑cohesive or loosely cohesive, with a polygonal morphology and prominent rhabdoid feature, showing eccentric vesicular nuclei, prominent nucleoli and abundant eosinophilic cytoplasm. Immunohistochemically, the tumor cells were positive for cytokeratin (CK) and vimentin, but negative for CK20, CK7, desmin and smooth muscle actin. This indicated a diagnosis of poorly differentiated adenocarcinoma with prominent rhabdoid features, combined with appendiceal mucinous cystadenoma. At two months following surgery the patient succumbed to peritoneal seeding and metastasis of liver and bone The emergence of the rhabdoid phenotype is invariably associated with an aggressive and almost always fatal clinical course. The present case is the 10th example of such a tumor in the colon, and to the best of our knowledge, this is the first case of colonic rhabdoid tumor coinciding with appendiceal benign mucinous neoplasm.

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Journals

International Journal of Molecular Medicine

International Journal of Oncology

Molecular Medicine Reports

Oncology Reports

Experimental and Therapeutic Medicine

Oncology Letters

Biomedical Reports

Molecular and Clinical Oncology

World Academy of Sciences Journal

International Journal of Functional Nutrition

International Journal of Epigenetics

Medicine International

Poorly differentiated cecal adenocarcinoma showing prominent rhabdoid feature combined with appendiceal mucinous cystadenoma: A case report and review of the literature

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