Diagnosis and treatment of penile verrucous carcinoma

Li,Fangyin; Xu,Yipeng; Wang,Hua; Chen,Bo; Wang,Zongping; Zhao,Yang; Zhu,Shaoxing; Chen,Guiping

doi:10.3892/ol.2015.2909

April-2015 Volume 9 Issue 4

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April-2015 Volume 9 Issue 4

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Article

Diagnosis and treatment of penile verrucous carcinoma

Authors:
- Fangyin Li
- Yipeng Xu
- Hua Wang
- Bo Chen
- Zongping Wang
- Yang Zhao
- Shaoxing Zhu
- Guiping Chen
View Affiliations / Copyright

Affiliations: Department of Urology, Zhejiang Cancer Hospital, Hangzhou, Zhejiang 310022, P.R. China, Department of Pathology, Zhejiang Cancer Hospital, Hangzhou, Zhejiang 310022, P.R. China
Pages: 1687-1690
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Published online on: January 27, 2015

https://doi.org/10.3892/ol.2015.2909
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Abstract

Penile verrucous carcinoma is an extremely rare disease that, at present, has not been well characterized. The etiology, diagnosis and treatment of this carcinoma remain poorly understood, particularly in the Chinese population. The aim of the present study was to discuss the methods of diagnosis and treatment of penile verrucous carcinoma in the Chinese population. The clinical and pathological data of 10 patients with penile verrucous carcinoma were analyzed alongside a literature review. All the tumors were exophytic papillary lesions, ranging between 0.4 and 4 cm in diameter and all 10 patients underwent partial penectomy with tumor‑negative surgical margins. None of the 10 patients underwent ilioinguinal lymphadenectomy. All patients were regularly followed up for 0.7‑9 years, which revealed that no patients developed recurrence, and only one case resulted in mortality due to unassociated causes. It was found that penile verrucous carcinoma is a well‑differentiated disease with low malignant potential and locally aggressive features, which seldom metastasizes to regional lymph nodes or distant regions. However, misdiagnosis may occur due to an incorrect biopsy. Favorable outcomes can be achieved by surgery, even without any adjuvant therapy, but patients should be carefully followed up.

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Journals

International Journal of Molecular Medicine

International Journal of Oncology

Molecular Medicine Reports

Oncology Reports

Experimental and Therapeutic Medicine

Oncology Letters

Biomedical Reports

Molecular and Clinical Oncology

World Academy of Sciences Journal

International Journal of Functional Nutrition

International Journal of Epigenetics

Medicine International

Diagnosis and treatment of penile verrucous carcinoma

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Abstract

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