Coexistence of benign struma ovarii, pseudo-Meigs' syndrome and elevated serum CA 125: Case report and review of the literature

Jin,Chengjuan; Dong,Ruiying; Bu,Hualei; Yuan,Mingyuan; Zhang,Youzhong; Kong,Beihua

doi:10.3892/ol.2015.2927

April-2015 Volume 9 Issue 4

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April-2015 Volume 9 Issue 4

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Case Report

Coexistence of benign struma ovarii, pseudo-Meigs' syndrome and elevated serum CA 125: Case report and review of the literature

Authors:
- Chengjuan Jin
- Ruiying Dong
- Hualei Bu
- Mingyuan Yuan
- Youzhong Zhang
- Beihua Kong
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Affiliations: Department of Obstetrics and Gynecology, Qilu Hospital, Shandong University, Jinan, Shandong 250012, P.R. China, Department of Obstetrics and Gynecology, Jiaozhou Central Hospital of Qingdao, Qingdao, Shandong 266300, P.R. China
Pages: 1739-1742
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Published online on: February 3, 2015

https://doi.org/10.3892/ol.2015.2927
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Abstract

Struma ovarii is an uncommon ovarian teratoma comprised predominantly of mature thyroid tissue. The combination of pseudo‑Meigs' syndrome, and elevation of CA 125 to the struma ovarii is a rare condition that can mimic ovarian malignancy. We reported a case of benign struma ovarii, presenting with the clinical features of advanced ovarian carcinoma: complex pelvic mass, gross ascites, bilateral pleural effusion and markedly elevated serum CA 125 levels. The patient underwent total abdominal hysterectomy and bilateral salpingo‑oophorectomy. Ascites and pleural effusion were not evident and the CA 125 levels returned to normal following surgical excision. A systematic review of reported cases of coexistent benign struma ovarii, pseudo‑Meigs' syndrome and elevated serum CA 125 was performed. Struma ovarii accompanied by pseudo‑Meigs' syndrome and elevated serum CA 125 should be considered in the differential diagnosis of ovarian epithelial cancer.

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