|
1
|
Jemal A, Siegel R, Xu J and Ward E: Cancer
statistics, 2010. CA Cancer J Clin. 60:277–300. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Lee S, Choi EJ, Jin C and Kim DH:
Activation of PI3K/Akt pathway by PTEN reduction and PIK3CA mRNA
amplification contributes to cisplatin resistance in an ovarian
cancer cell line. Gynecol Oncol. 97:26–34. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Hara T, Nakamura K, Matsui M, et al:
Suppression of basal autophagy in neural cells causes
neurodegenerative disease in mice. Nature. 441:885–889. 2006.
View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Huang X, Bai HM, Chen I, Li B and Lu YC:
Reduced expression of LC3B-II and Beclin 1 in glioblastoma
multiforme indicates a down-regulated autophagic capacity that
relates to the progression of astrocytic tumors. J Clin Neurosci.
17:1515–1519. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Koren I and Kimchi A: Cell biology.
Promoting tumorigenesis by suppressing autophagy. Science.
338:889–890. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Lin HX, Qiu HJ, Zeng F, et al: Decreased
expression of Beclin 1 correlates closely with Bcl-xL expression
and poor prognosis of ovarian carcinoma. PLoS One. 8:e605162013.
View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Yao Q, Chen J, Lv Y, et al: The
significance of expression of autophagy-related gene Beclin, Bcl-2,
and Bax in breast cancer tissues. Tumour Biol. 32:1163–1171. 2011.
View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Xu LW, Qian M, Jia RP, et al: Expression
and significance of microsomal prostaglandin synthase-1 (mPGES-1)
and Beclin-1 in the development of prostate cancer. Asian Pac J
Cancer Prev. 13:1639–1644. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Wan XB, Fan XJ, Chen MY, et al: Elevated
Beclin 1 expression is correlated with HIF-1alpha in predicting
poor prognosis of nasopharyngeal carcinoma. Autophagy. 6:395–404.
2010. View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Yue Z, Jin S, Yang C, Levine AJ and Heintz
N: Beclin 1, an autophagy gene essential for early embryonic
development, is a haploinsufficient tumor suppressor. Proc Natl
Acad Sci USA. 100:15077–15082. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Pecorelli S: Revised FIGO staging for
carcinoma of the vulva, cervix, and endometrium. Int J Gyneeol
Obstet. 105:103–111. 2009. View Article : Google Scholar
|
|
12
|
Kondo Y and Kondo S: Autophagy and cancer
therapy. Autophagy. 2:85–90. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Li DM and Sun H: TEP1, encoded by a
candidate tumor suppressor locus, is a novel protein tyrosine
phosphatase regulated by transforming growth factor beta. Cancer
Res. 57:2124–2129. 1997.PubMed/NCBI
|
|
14
|
Li DM and Sun H: TEP1, encoded by a
candidate tumor suppressor locus, is a novel protein tyrosine
phosphatase regulated by transforming growth factor beta. Cancer
Res. 57:2124–2129. 1997.PubMed/NCBI
|
|
15
|
Lee H, Choi HJ, Kang CS, Lee HJ, Lee WS
and Park CS: Expression of miRNAs and PTEN in endometrial specimens
ranging from histologically normal to hyperplasia and endometrial
adenocarcinoma. Mod Pathol. 25:1508–1515. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Patel R, Gao M, Ahmad I, Fleming J, Singh
LB, Rai TS, McKie AB, Seywright M, Barnetson RJ, Edwards J, et al:
Sprouty2, PTEN, and PP2A interact to regulate prostate cancer
progression. J Clin Invest. 123:1157–1175. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Molina JR, Agarwal NK, Morales FC, Hayashi
Y, Aldape KD, Cote G and Georgescu MM: PTEN, NHERF1 and PHLPP form
a tumor suppressor network that is disabled in glioblastoma.
Oncogene. 31:1264–1274. 2012. View Article : Google Scholar
|
|
18
|
Yang L, Kuang LG, Zheng HC, et al: PTEN
encoding product: a marker for tumorigenesis and progression of
gastric carcinoma. World J Gastroenterol. 9:35–39. 2003.PubMed/NCBI
|
|
19
|
Laudański P, Kowalczuk O,
Klasa-Mazurkiewicz D, et al: Selective gene expression profiling of
mTOR-associated tumor suppressor and oncogenes in ovarian cancer.
Folia Histochem Cytobiol. 49:317–324. 2011. View Article : Google Scholar
|
|
20
|
Skírnisdóttir I and Seidal T: Prognostic
impact of concomitant p53 and PTEN on outcome in early stage (FIGO
I-II) epithelial ovarian cancer. Int J Gynecol Cancer.
21:1024–1031. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Gadducci A, Guerrieri ME and Genazzani AR:
New insights on the pathogenesis of ovarian carcinoma: molecular
basis and clinical implications. Gynecol Endocrinol. 28:582–586.
2012. View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Selvendiran K, Tong L, Vishwanath S, et
al: EF24 induces G2/M arrest and apoptosis in cisplatin-resistant
human ovarian cancer cells by increasing PTEN expression. J Biol
Chem. 282:28609–28618. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Wu HJ, Wu HT, Weng DH, et al: Reversal of
drug resistance in human ovarian cancer ceils by wild-type PTEN
gene and its mechanisms. Zhonghua Fu Chan Ke Za Zhi. 42:612–616.
2007.(In Chinese). PubMed/NCBI
|
|
24
|
Yan X, Fraser M, Qiu Q and Tsang BK:
Over-expression of PTEN sensitizes human ovarian cancer cells to
cisplatin-induced apoptosis in a p53-dependent manner. Gynecol
Oncol. 102:348–355. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
25
|
Scarlatti F, Maffei R, Beau I, Codogno P
and Ghidoni R: Role of non-canonical Beclin 1-independent autophagy
in cell death induced by resveratrol in human breast cancer cells.
Cell Death Differ. 15:1318–1329. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Sun Y, Liu JH, Jin L, et al:
Over-expression of the Beclin1 gene upregulates chemosensitivity to
anti-cancer drugs by enhancing therapy-induced apoptosis in cervix
squamous carcinoma CaSki cells. Cancer Lett. 294:204–210. 2010.
View Article : Google Scholar : PubMed/NCBI
|
|
27
|
Levine B and Kroemer G: Autophagy in the
pathogenesis of disease. Cell. 132:27–42. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Kimmelman AC: The dynamic nature of
autophagy in cancer. Genes Dev. 25:1999–2010. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
29
|
Ahn CH, Jeong EG, Lee JW, et al:
Expression of beclin-l, an autophagy-related protein, in gastric
and colorectal cancers. APMIS. 115:1344–1349. 2007. View Article : Google Scholar
|
|
30
|
Tang H, Da L, Mao Y, et al: Hepatitis B
virus X protein sensitizes cells to starvation-induced autophagy
via up-regulation of beclin 1 expression. Hepatology. 49:60–71.
2009. View Article : Google Scholar
|
|
31
|
Edinger AL and Thompson CB: Defective
autophagy leads to cancer. Cancer Cell. 4:422–424. 2003. View Article : Google Scholar
|
