|
1
|
Wang Z, Cao Y, Jiang C, Yang G, Wu J and
Ding Y: Lack of association of two common polymorphisms rs2910164
and rs11614913 with susceptibility to hepatocellular carcinoma: A
meta-analysis. PLoS One. 7:e400392012. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Thomas MB, Jaffe D, Choti MM, Belghiti J,
Curley S, Fong Y, Gores G, Kerlan R, Merle P, O'Neil B, et al:
Hepatocellular carcinoma: Consensus recommendations of the National
Cancer Institute Clinical Trials Planning Meeting. J Clin Oncol.
28:3994–4005. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Lao Y, Wu H, Zhao C, Wu Q, Qiao F and Fan
H: Promoter polymorphisms of DNA methyltransferase 3B and risk of
hepatocellular carcinoma. Biomed Rep. 1:771–775. 2013.PubMed/NCBI
|
|
4
|
Miyake T, Endo K, Honjo S, Hirooka Y and
Ikeguchi M: Expression of DNA methyltransferase (DNMT) 1, 3a and 3b
proteins in human hepatocellular carcinoma. Yonago Acta Med.
53:1–7. 2010.
|
|
5
|
Lee S, Lee HJ, Kim JH, Lee HS, Jang JJ and
Kang GH: Aberrant CpG island hypermethylation along multistep
hepatocarcinogenesis. Am J Pathol. 163:1371–1378. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Roncalli M, Bianchi P, Bruni B, Laghi L,
Destro A, Di Gioia S, Gennari L, Tommasini M, Malesci A and Coggi
G: Methylation framework of cell cycle gene inhibitors in cirrhosis
and associated hepatocellular carcinoma. Hepatology. 36:427–432.
2002. View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Yang B, Guo M, Herman JG and Clark DP:
Aberrant promoter methylation profiles of tumor suppressor genes in
hepatocellular carcinoma. Am J Pathol. 163:1101–1107. 2003.
View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Robertson KD and Wolffe AP: DNA
methylation in health and disease. Nat Rev Genet. 1:11–19. 2000.
View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Jones PA and Baylin SB: The fundamental
role of epigenetic events in cancer. Nat Rev Genet. 3:415–428.
2002.PubMed/NCBI
|
|
10
|
Jones PA: Functions of DNA methylation:
Islands, start sites, gene bodies and beyond. Nat Rev Genet.
13:484–492. 2012. View
Article : Google Scholar : PubMed/NCBI
|
|
11
|
Hsieh CL: The de novo methylation activity
of Dnmt3a is distinctly different than that of Dnmt1. BMC Biochem.
6:62005. View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Bestor TH: The DNA methyltransferases of
mammals. Hum Mol Genet. 9:2395–2402. 2000. View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Oh BK, Kim H, Park HJ, Shim YH, Choi J,
Park C and Park YN: DNA methyltransferase expression and DNA
methylation in human hepatocellular carcinoma and their
clinicopathological correlation. Int J Mol Med. 20:65–73.
2007.PubMed/NCBI
|
|
14
|
Baylin S and Bestor TH: Altered
methylation patterns in cancer cell genomes: Cause or consequence?
Cancer Cell. 1:299–305. 2002. View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Robertson KD: DNA methylation and human
disease. Nat Rev Genet. 6:597–610. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Shen J, Wang S, Zhang YJ, Kappil M, Wu HC,
Kibriya MG, Wang Q, Jasmine F, Ahsan H, Lee PH, et al: Genome-wide
DNA methylation profiles in hepatocellular carcinoma. Hepatology.
55:1799–1808. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Lambert MP, Paliwal A, Vaissière T, Chemin
I, Zoulim F, Tommasino M, Hainaut P, Sylla B, Scoazec JY, Tost J,
et al: Aberrant DNA methylation distinguishes hepatocellular
carcinoma associated with HBV and HCV infection and alcohol intake.
J Hepatol. 54:705–715. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Um TH, Kim H, Oh BK, Kim MS, Kim KS, Jung
G and Park YN: Aberrant CpG island hypermethylation in dysplastic
nodules and early HCC of hepatitis B virus-related human multistep
hepatocarcinogenesis. J Hepatol. 54:939–947. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Hu L, Chen G, Yu H and Qiu X:
Clinicopathological significance of RASSF1A reduced expression and
hypermethylation in hepatocellular carcinoma. Hepatol Int.
4:423–432. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Kondo Y, Shen L, Suzuki S, Kurokawa T,
Masuko K, Tanaka Y, Kato H, Mizuno Y, Yokoe M, Sugauchi F, et al:
Alterations of DNA methylation and histone modifications contribute
to gene silencing in hepatocellular carcinomas. Hepatol Res.
37:974–983. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Yeo W, Wong N, Wong WL, Lai PB, Zhong S
and Johnson PJ: High frequency of promoter hypermethylation of
RASSF1A in tumor and plasma of patients with hepatocellular
carcinoma. Liver Int. 25:266–272. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Csepregi A, Röcken C, Hoffmann J, Gu P,
Saliger S, Müller O, Schneider-Stock R, Kutzner N, Roessner A,
Malfertheiner P, et al: APC promoter methylation and protein
expression in hepatocellular carcinoma. J Cancer Res Clin Oncol.
134:579–589. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Zopf S, Ocker M, Neureiter D, Alinger B,
Gahr S, Neurath MF and Di Fazio P: Inhibition of DNA
methyltransferase activity and expression by treatment with the
pan-deacetylase inhibitor panobinostat in hepatocellular carcinoma
cell lines. BMC Cancer. 12:3862012. View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Steine EJ, Ehrich M, Bell GW, Raj A, Reddy
S, van Oudenaarden A, et al: Genes methylated by DNA
methyltransferase 3b are similar in mouse intestine and human colon
cancer. J Clin Invest. 121:1748–1752. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
25
|
Rhee I, Bachman KE, Park BH, Jair KW, Yen
RW, Schuebel KE, et al: DNMT1 and DNMT3b cooperate to silence genes
in human cancer cells. Nature. 416:552–556. 2002. View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Jin B and Robertson KD: DNA
methyltransferases, DNA damage repair, and cancer. Adv Exp Med
Biol. 754:3–29. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
27
|
Xu J, Fan H, Zhao ZJ, Zhang JQ and Xie W:
Identification of potential genes regulated by DNA
methyltransferase 3B in a hepatocellular carcinoma cell line by RNA
interference and microarray analysis. Yi Chuan Xue Bao.
32:1115–1127. 2005.PubMed/NCBI
|
|
28
|
Du YF, Liang L, Shi Y, Long QZ, Zeng J,
Wang XY and He DL: Multi-target siRNA based on DNMT3A/B homologous
conserved region influences cell cycle and apoptosis of human
prostate cancer cell line TSU-PR1. Genet Mol Biol. 35:164–171.
2012. View Article : Google Scholar : PubMed/NCBI
|
|
29
|
Kassis ES, Zhao M, Hong JA, Chen GA,
Nguyen DM and Schrump DS: Depletion of DNA methyltransferase 1
and/or DNA methyltransferase 3b mediates growth arrest and
apoptosis in lung and esophageal cancer and malignant pleural
mesothelioma cells. J Thorac Cardiovasc Surg. 131:298–306. 2006.
View Article : Google Scholar : PubMed/NCBI
|
|
30
|
Beaulieu N, Morin S, Chute IC, Robert MF,
Nguyen H and MacLeod AR: An essential role for DNA
methyltransferase DNMT3B in cancer cell survival. J Biol Chem.
277:28176–28181. 2002. View Article : Google Scholar : PubMed/NCBI
|
|
31
|
Yaqinuddin A, Qureshi SA, Qazi R and Abbas
F: Down-regulation of DNMT3b in PC3 cells effects locus-specific
DNA methylation, and represses cellular growth and migration.
Cancer Cell Int. 8:132008. View Article : Google Scholar : PubMed/NCBI
|
|
32
|
Lin CH, Hsieh SY, Sheen IS, Lee WC, Chen
TC, Shyu WC and Liaw YF: Genome-wide hypomethylation in
hepatocellular carcinogenesis. Cancer Res. 61:4238–4243.
2001.PubMed/NCBI
|
|
33
|
Teneng I, Tellez CS, Picchi MA, et al:
Global identification of genes targeted by DNMT3b for epigenetic
silencing in lung cancer. Oncogene. 34:621–630. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
34
|
Xie F, Ye L, Ta M, Zhang L and Jiang WG:
MTSS1: a multifunctional protein and its role in cancer invasion
and metastasis. Front Biosci (Schol Ed). 3:621–631. 2011.
View Article : Google Scholar : PubMed/NCBI
|
|
35
|
Fan H, Chen L, Zhang F, Quan Y, Su X, Qiu
X, Zhao Z, Kong KL, Dong S, Song Y, et al: MTSS1, a novel target of
DNA methyltransferase 3B, functions as a tumor suppressor in
hepatocellular carcinoma. Oncogene. 31:2298–2308. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
36
|
Wang J, Li J, Shen J, Wang C, Yang L and
Zhang X: MicroRNA-182 downregulates metastasis suppressor 1 and
contributes to metastasis of hepatocellular carcinoma. BMC Cancer.
12:2272012. View Article : Google Scholar : PubMed/NCBI
|
|
37
|
Wang J, Bhutani M, Pathak AK, Lang W, Ren
H, Jelinek J, He R, Shen L, Issa JP and Mao L: Delta DNMT3B
variants regulate DNA methylation in a promoter-specific manner.
Cancer Res. 67:10647–10652. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
38
|
Linhart HG, Lin H, Yamada Y, Moran E,
Steine EJ, Gokhale S, Lo G, Cantu E, Ehrich M, He T, et al: Dnmt3b
promotes tumorigenesis in vivo by gene-specific de novo methylation
and transcriptional silencing. Genes Dev. 21:3110–3122. 2007.
View Article : Google Scholar : PubMed/NCBI
|
|
39
|
Sarli L, Bottarelli L, Azzoni C, Campanini
N, Di Cola G, Bader G, Iusco D, Salvemini C, Caruso G, Donadei E,
et al: Abnormal Fhit protein expression and high frequency of
microsatellite instability in sporadic colorectal cancer. Eur J
Cancer. 40:1581–1588. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
40
|
Nelson WG, De Marzo AM and DeWeese TL: The
molecular pathogenesis of prostate cancer: Implications for
prostate cancer prevention. Urology. 57:(Suppl 1). 39–45. 2001.
View Article : Google Scholar : PubMed/NCBI
|
|
41
|
Wang JX, Zhang YG and Zhao LS: Influence
of DNA methyltransferase 3b on FHIT expression and DNA methylation
of the FHIT promoter region in hepatoma SMMC-7721 cells.
Hepatobiliary Pancreat Dis Int. 8:273–277. 2009.PubMed/NCBI
|
