Successful treatment of quintuple primary cancer, including esophageal cancer: A case report

Otowa,Yasunori; Nakamura,Tetsu; Takiguchi,Gosuke; Urakawa,Naoki; Ishida,Ryo; Imanishi,Tatsuya; Suzuki,Satoshi; Tanaka,Kenichi; Kuroda,Daisuke; Kakeji,Yoshihiro

doi:10.3892/ol.2015.3082

June-2015 Volume 9 Issue 6

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June-2015 Volume 9 Issue 6

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Case Report

Successful treatment of quintuple primary cancer, including esophageal cancer: A case report

Authors:
- Yasunori Otowa
- Tetsu Nakamura
- Gosuke Takiguchi
- Naoki Urakawa
- Ryo Ishida
- Tatsuya Imanishi
- Satoshi Suzuki
- Kenichi Tanaka
- Daisuke Kuroda
- Yoshihiro Kakeji
View Affiliations / Copyright

Affiliations: Department of Surgery, Division of Gastrointestinal Surgery, Kobe University Graduate School of Medicine, Kobe, Japan, Department of Surgery, Kita‑Harima Medical Center, Ono, Hyogo, Japan
Pages: 2583-2585
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Published online on: March 27, 2015

https://doi.org/10.3892/ol.2015.3082
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Abstract

The present study reports the rare case of a patient with quintuple primary cancer that underwent systematic treatment, including surgical intervention. A 63‑year‑old male patient was initially diagnosed with primary esophageal cancer and hypopharyngeal cancer. The patient underwent total pharyngolaryngoesophagectomy using a thoracoscopic method and reconstruction using the free jejunal flap and gastric tube and was subsequently administered adjuvant chemotherapy (80 mg/m2 intravenously on day 1, cisplatin; 800 mg/m2 continuous intravenous administration on days 1-5, 5‑fluorouracil). At 66 years old, the patient was diagnosed with left maxillary sinus cancer and underwent chemoradiotherapy (four 100 mg/m2 arterial cisplatin injections; 70 Gy/35 f radiotherapy, 2 Gy per day over 35 days). At 68 years old, the patient was diagnosed with gastric tube cancer and underwent gastric tube resection followed by pedicled jejunum flap reconstruction. At 69 years old, the patient was diagnosed with tongue cancer and underwent resection and reconstruction of the tongue by pectoralis major myocutaneous flap. Six years subsequent to the primary surgery, the patient remains alive, without metastasis of the lesions. To the best of our knowledge, the present study is the first report of a patient that underwent a curative procedure for the treatment of five primary multiple cancers in five organs, including esophageal cancer.

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Journals

International Journal of Molecular Medicine

International Journal of Oncology

Molecular Medicine Reports

Oncology Reports

Experimental and Therapeutic Medicine

Oncology Letters

Biomedical Reports

Molecular and Clinical Oncology

World Academy of Sciences Journal

International Journal of Functional Nutrition

International Journal of Epigenetics

Medicine International

Successful treatment of quintuple primary cancer, including esophageal cancer: A case report

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