Comparison of the clinical value of multi-band mucosectomy versus endoscopic mucosal resection for the treatment of patients with early-stage esophageal cancer

Chen,Zi‑Yang; Yang,Yun‑Chao; Liu,Li‑Mei; Liu,Xiao‑Gang; Li,Yi; Li,Liang‑Ping; Hu,Xiao; Zhang,Ren‑Yi; Song,Yan; Qin,Qin

doi:10.3892/ol.2015.3098

June-2015 Volume 9 Issue 6

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June-2015 Volume 9 Issue 6

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Article

Comparison of the clinical value of multi-band mucosectomy versus endoscopic mucosal resection for the treatment of patients with early-stage esophageal cancer

Authors:
- Zi‑Yang Chen
- Yun‑Chao Yang
- Li‑Mei Liu
- Xiao‑Gang Liu
- Yi Li
- Liang‑Ping Li
- Xiao Hu
- Ren‑Yi Zhang
- Yan Song
- Qin Qin
View Affiliations / Copyright

Affiliations: Department of Digestion, Sichuan Academy of Medical Sciences and Sichuan Provincial People's Hospital, Chengdu, Sichuan 610072, P.R. China
Pages: 2716-2720
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Published online on: April 2, 2015

https://doi.org/10.3892/ol.2015.3098
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Abstract

The present study aimed to compare the clinical value of multi-band mucosectomy (MBM) versus endoscopic mucosal resection (EMR) for the treatment of patients with early‑stage esophageal cancer. Between January 2011 and December 2012, 68 patients with early‑stage esophageal cancer who underwent MBM and EMR were enrolled into the present study. The curative resection rate, duration of surgery, complications and follow‑up records were retrospectively analyzed. Of the 68 patients included, 33 were treated with MBM and 35 with EMR. There was no significant difference in the rate of complete resection between the MBM and EMR groups (P>0.05). The mean duration of surgery in the MBM group was statistically lower than that in the EMR group (P<0.05). There was no statistically significant difference in the intraoperative and post‑operative complications between the MBM and EMR groups (P>0.05). Esophageal cancer reoccurred in 2 patients treated with MBM and 1 patient treated with EMR during the follow‑up period (range, 3‑24 months). Overall, MBM can be considered a better surgical option for the management of patients with early‑stage esophageal cancer, as it offers higher histological curative resection rates and improved safety. However, further studies and a larger follow‑up period are required to confirm the long-term curative effect.

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Journals

International Journal of Molecular Medicine

International Journal of Oncology

Molecular Medicine Reports

Oncology Reports

Experimental and Therapeutic Medicine

Oncology Letters

Biomedical Reports

Molecular and Clinical Oncology

World Academy of Sciences Journal

International Journal of Functional Nutrition

International Journal of Epigenetics

Medicine International

Comparison of the clinical value of multi-band mucosectomy versus endoscopic mucosal resection for the treatment of patients with early-stage esophageal cancer

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Abstract

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