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Oncology Letters
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Print ISSN: 1792-1074 Online ISSN: 1792-1082
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September-2015 Volume 10 Issue 3

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International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

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International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

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Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

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Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

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Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

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Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

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Molecular and Clinical Oncology

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International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

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Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

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International Journal of Functional Nutrition

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International Journal of Epigenetics

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Case Report

Hepatoid adenocarcinoma of the stomach: Nine case reports and treatment outcomes

  • Authors:
    • Cheng Xiao
    • Fusheng Wu
    • Han Jiang
    • Lisong Teng
    • Fang Song
    • Qiangfeng Wang
    • Huanxia Yang
  • View Affiliations / Copyright

    Affiliations: Department of Surgical Oncology, First Affiliated Hospital, Zhejiang University, School of Medicine, Hangzhou, Zhejiang 310003, P.R. China, Department of Anesthesiology, First Affiliated Hospital, Zhejiang University, School of Medicine, Hangzhou, Zhejiang 310003, P.R. China
  • Pages: 1605-1609
    |
    Published online on: June 29, 2015
       https://doi.org/10.3892/ol.2015.3430
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Abstract

Hepatoid adenocarcinoma (HAC), an extrahepatic tumor, has notable morphological similarities to hepatocellular carcinoma, which has been reported in gastrointestinal tract organs, including the rectum, gallbladder, lung, ovary and urinary bladder. HAC of the stomach (GHAC) is a rare variant of gastric cancer, characterized by aggressive behavior and extremely poor prognosis. Correct diagnosis depends on clinicopathological and immunohistochemical studies. In the present study, we reported nine cases of GHAC who were treated in the First Affiliated Hospital of Zhejiang University, China, from January 2009 to December 2013. All patients underwent radical gastrectomy; among them, one patient had stage I, one had stage II and seven had stage III. Elevated serum α‑fetoprotein was observed in eight cases. Until now, only one patient has succumbed, four patients have liver metastases, one has lung metastasis and four remain disease‑free. Relatively longer survival requires accurate diagnosis at an earlier stage and active multimodality treatment, including radical gastrectomy and adjuvant chemotherapy.
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Copy and paste a formatted citation
Spandidos Publications style
Xiao C, Wu F, Jiang H, Teng L, Song F, Wang Q and Yang H: Hepatoid adenocarcinoma of the stomach: Nine case reports and treatment outcomes. Oncol Lett 10: 1605-1609, 2015.
APA
Xiao, C., Wu, F., Jiang, H., Teng, L., Song, F., Wang, Q., & Yang, H. (2015). Hepatoid adenocarcinoma of the stomach: Nine case reports and treatment outcomes. Oncology Letters, 10, 1605-1609. https://doi.org/10.3892/ol.2015.3430
MLA
Xiao, C., Wu, F., Jiang, H., Teng, L., Song, F., Wang, Q., Yang, H."Hepatoid adenocarcinoma of the stomach: Nine case reports and treatment outcomes". Oncology Letters 10.3 (2015): 1605-1609.
Chicago
Xiao, C., Wu, F., Jiang, H., Teng, L., Song, F., Wang, Q., Yang, H."Hepatoid adenocarcinoma of the stomach: Nine case reports and treatment outcomes". Oncology Letters 10, no. 3 (2015): 1605-1609. https://doi.org/10.3892/ol.2015.3430
Copy and paste a formatted citation
x
Spandidos Publications style
Xiao C, Wu F, Jiang H, Teng L, Song F, Wang Q and Yang H: Hepatoid adenocarcinoma of the stomach: Nine case reports and treatment outcomes. Oncol Lett 10: 1605-1609, 2015.
APA
Xiao, C., Wu, F., Jiang, H., Teng, L., Song, F., Wang, Q., & Yang, H. (2015). Hepatoid adenocarcinoma of the stomach: Nine case reports and treatment outcomes. Oncology Letters, 10, 1605-1609. https://doi.org/10.3892/ol.2015.3430
MLA
Xiao, C., Wu, F., Jiang, H., Teng, L., Song, F., Wang, Q., Yang, H."Hepatoid adenocarcinoma of the stomach: Nine case reports and treatment outcomes". Oncology Letters 10.3 (2015): 1605-1609.
Chicago
Xiao, C., Wu, F., Jiang, H., Teng, L., Song, F., Wang, Q., Yang, H."Hepatoid adenocarcinoma of the stomach: Nine case reports and treatment outcomes". Oncology Letters 10, no. 3 (2015): 1605-1609. https://doi.org/10.3892/ol.2015.3430
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