Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Oncology Letters
      • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Biomedical Reports
      • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • Information for Authors
    • Information for Reviewers
    • Information for Librarians
    • Information for Advertisers
    • Conferences
  • Language Editing
Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • For Authors
    • For Reviewers
    • For Librarians
    • For Advertisers
    • Conferences
  • Language Editing
Login Register Submit
  • This site uses cookies
  • You can change your cookie settings at any time by following the instructions in our Cookie Policy. To find out more, you may read our Privacy Policy.

    I agree
Search articles by DOI, keyword, author or affiliation
Search
Advanced Search
presentation
Oncology Letters
Join Editorial Board Propose a Special Issue
Print ISSN: 1792-1074 Online ISSN: 1792-1082
Journal Cover
October-2015 Volume 10 Issue 4

Full Size Image

Sign up for eToc alerts
Recommend to Library

Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

Journal Cover
October-2015 Volume 10 Issue 4

Full Size Image

Sign up for eToc alerts
Recommend to Library

  • Article
  • Citations
    • Cite This Article
    • Download Citation
    • Create Citation Alert
    • Remove Citation Alert
    • Cited By
  • Similar Articles
    • Related Articles (in Spandidos Publications)
    • Similar Articles (Google Scholar)
    • Similar Articles (PubMed)
  • Download PDF
  • Download XML
  • View XML
Case Report Open Access

Primary skeletal muscle diffuse large B cell lymphoma: A case report and review of the literature

  • Authors:
    • Lijuan Zhang
    • Quande Lin
    • Lina Zhang
    • Lihua Dong
    • Yufu Li
  • View Affiliations / Copyright

    Affiliations: Transplantation Department of Internal Medicine, 302 Hospital of the Chinese People's Liberation Army, Beijing 100039, P.R. China, Department of Hematology, Affiliated Cancer Hospital of Zhengzhou University, Zhengzhou, Henan 450008, P.R. China
    Copyright: © Zhang et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Pages: 2156-2160
    |
    Published online on: July 17, 2015
       https://doi.org/10.3892/ol.2015.3505
  • Expand metrics +
Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )
Metrics: Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )
Cited By (CrossRef): 0 citations Loading Articles...

This article is mentioned in:



Abstract

The occurrence of primary extranodal non-Hodgkin's lymphoma (NHL) of soft tissue is rare, particularly in skeletal muscle. The present study describes a case of diffuse large B cell lymphoma of the right lower extremity and provides a detailed review of the literature associated with this disorder, with the aim of improving the future diagnosis and therapy of extranodal NHL. The present case report was of a 76‑year‑old woman who presented with a right thigh and calf mass. In view of the tumor's location and the patient's age, soft tissue tumors were considered to be soft tissue sarcoma. Imaging scans were performed to determine the location and size of the tumor, followed by a biopsy of the muscle. Histopathological examination then yielded a diagnosis of diffuse large B cell lymphoma. The patient then underwent 4 cycles of chemotherapy. There was evident relief of pain and swelling in the right extremity; however, positron emission tomography/computed tomography (PET/CT) determined insufficient treatment efficacy. Chemotherapy was adjusted for 2 cycles; however, the patient suffered an aggravation of edema, so a different chemotherapy regimen of bleomycin, cytarabine, vincristine, cyclosphamide and dexamethasone (BCOAD) was performed for a further 2 cycles. The edema was alleviated and magnetic resonance imaging revealed shrinkage of the lower limb mass and the right thigh mass was undetectable. In conclusion, the present case report demonstrated that PET/CT may help determine the efficacy of chemotherapy treatment and that the BCOAD chemotherapy regimen may be more effective than standard treatments in certain cases.
View Figures

Figure 1

Figure 2

Figure 3

View References

1 

Yancik R and Ries LA: Cancer in older persons: An international issue in an aging world. Semin Oncol. 31:128–136. 2004. View Article : Google Scholar : PubMed/NCBI

2 

Flowers CR, Sinha R and Vose JM: Improving outcomes for patients with diffuse large B-cell lymphoma. CA Cancer J Clin. 60:393–408. 2010.PubMed/NCBI

3 

Freeman C, Berg JW and Cutler SJ: Occurrence and prognosis of extranodal lymphomas. Cancer. 29:252–260. 1972. View Article : Google Scholar : PubMed/NCBI

4 

Bourdeanu L, Menon R and Somlo G: Diffuse large B-cell lymphoma with calf muscle localization. Case Rep Hematol. 2011:2924942011.PubMed/NCBI

5 

Lee VS, Martinez S and Coleman RE: Primary muscle lymphoma: Clinical and imaging findings. Radiology. 203:237–244. 1997. View Article : Google Scholar : PubMed/NCBI

6 

Talaulikar D, Shadbolt B, Dahlstrom JE and McDonald A: Routine use of ancillary investigations in staging diffuse large B-cell lymphoma improves the International Prognostic Index (IPI). J Hematol Oncol. 2:492009. View Article : Google Scholar : PubMed/NCBI

7 

Kandel RA, Bédard YC, Pritzker KP and Luk SC: Lymphoma. Presenting as an intramuscular small cell malignant tumor. Cancer. 53:1586–1589. 1984. View Article : Google Scholar : PubMed/NCBI

8 

Glass AG, Karnell LH and Menck HR: The National Cancer Data Base report on non-Hodgkin's lymphoma. Cancer. 80:2311–2320. 1997. View Article : Google Scholar : PubMed/NCBI

9 

Travis WD, Banks PM and Reiman HM: Primary extranodal soft tissue lymphoma of the extremities. Am J Surg Pathol. 11:359–366. 1987. View Article : Google Scholar : PubMed/NCBI

10 

Suresh S, Saifuddin A and O'Donnell P: Lymphoma presenting as a musculoskeletal soft tissue mass: MRI findings in 24 cases. Eur Radiol. 18:2628–2634. 2008. View Article : Google Scholar : PubMed/NCBI

11 

Hwang S: Imaging of lymphoma of the musculoskeletal system. Radiol Clin North Am. 46:379–396. 2008. View Article : Google Scholar : PubMed/NCBI

12 

Damron TA, Le MH, Rooney MT, Vermont A and Poiesz BJ: Lymphoma presenting as a soft tissue mass. A soft tissue sarcoma simulator. Clin Orthop Relat Res:221–230. 1999.

13 

Chun CW, Jee WH, Park HJ, Kim YJ, Park JM, Lee SH and Park SH: MRI features of skeletal muscle lymphoma. AJR Am J Roentgenol. 195:1355–1360. 2010. View Article : Google Scholar : PubMed/NCBI

14 

Hwang S: Imaging of lymphoma of the musculoskeletal system. Magn Reson Imaging Clin N Am. 18:75–93. 2010. View Article : Google Scholar : PubMed/NCBI

15 

Kang HJ, Beylergil V, Price AP, Abramson SJ and Carrasquillo JA: FDG PET/CT detection of intussusception caused by lymphoma in a pediatric patient. Clin Nucl Med. 39:97–98. 2014. View Article : Google Scholar : PubMed/NCBI

16 

Knowles B and Serpell JW: Extra-nodal lymphoma presenting as a mimic of soft-tissue sarcoma. ANZ J Surg. 73:26–30. 2003. View Article : Google Scholar : PubMed/NCBI

17 

Coiffier B, Lepage E, Briere J, Herbrecht R, Tilly H, Bouabdallah R, Morel P, Van Den Neste E, Salles G, Gaulard P, et al: CHOP chemotherapy plus rituximab compared with CHOP alone in elderly patients with diffuse large-B-cell lymphoma. N Engl J Med. 346:235–242. 2002. View Article : Google Scholar : PubMed/NCBI

18 

Feugier P, Van Hoof A, Sebban C, Solal-Celigny P, Bouabdallah R, Fermé C, Christian B, Lepage E, Tilly H, Morschhauser F, et al: Long-term results of the R-CHOP study in the treatment of elderly patients with diffuse large B-cell lymphoma: A study by the Groupe d'Etude des Lymphomes de l'Adulte. J Clin Oncol. 23:4117–4126. 2005. View Article : Google Scholar : PubMed/NCBI

19 

Habermann TM, Weller EA, Morrison VA, Gascoyne RD, Cassileth PA, Cohn JB, Dakhil SR, Woda B, Fisher RI, Peterson BA, et al: Rituximab-CHOP versus CHOP alone or with maintenance rituximab in older patients with diffuse large B-cell lymphoma. J Clin Oncol. 24:3121–3127. 2006. View Article : Google Scholar : PubMed/NCBI

20 

Coiffier B, Thieblemont C, Van Den Neste E, Lepeu G, Plantier I, Castaigne S, Lefort S, Marit G, Macro M, Sebban C, et al: Long-term outcome of patients in the LNH-98.5 trial, the first randomized study comparing rituximab-CHOP to standard CHOP chemotherapy in DLBCL patients: A study by the Groupe d'Etudes des Lymphomes de l'Adulte. Blood. 116:2040–2045. 2010. View Article : Google Scholar : PubMed/NCBI

21 

Niitsu N: Current treatment strategy of diffuse large B-cell lymphomas. Int J Hematol. 92:231–237. 2010. View Article : Google Scholar : PubMed/NCBI

22 

Spina M, Balzarotti M, Uziel L, Ferreri AJ, Fratino L, Magagnoli M, Talamini R, Giacalone A, Ravaioli E, Chimienti E, et al: Modulated chemotherapy according to modified comprehensive geriatric assessment in 100 consecutive elderly patients with diffuse large B-cell lymphoma. Oncologist. 17:838–846. 2012. View Article : Google Scholar : PubMed/NCBI

23 

Huang Z, Xu Z and Zhou Y: Chemotherapy alone versus chemotherapy followed by consolidative radiotherapy for limited-stage aggressive non-Hodgkin's lymphoma: A meta-analysis of randomized controlled trials. Cancer Radiother. 17:736–743. 2013. View Article : Google Scholar : PubMed/NCBI

24 

Dorth JA, Prosnitz LR, Broadwater G, Beaven AW and Kelsey CR: Radiotherapy dose-response analysis for diffuse large B-cell lymphoma with a complete response to chemotherapy. Radiat Oncol. 7:1002012. View Article : Google Scholar : PubMed/NCBI

25 

Hou Y, Wang HQ and Ba Y: Rituximab, gemcitabine, cisplatin, and dexamethasone in patients with refractory or relapsed aggressive B-cell lymphoma. Med Oncol. 29:2409–2416. 2012. View Article : Google Scholar : PubMed/NCBI

26 

Aribi M, Mesli N, Remla N, Sari BE, Taleb A, Touhami H, Bekadja MA, ZouaouiBenhadji Z, Bouzid K and Meguenni K: Gemcitabine and treatment of diffuse large B-cell lymphoma in relapsed or refractory elderly patients: A prospective randomized trial in Algeria. J Cancer Res Ther. 6:41–46. 2010. View Article : Google Scholar : PubMed/NCBI

27 

Crump M, Baetz T, Couban S, Belch A, Marcellus D, HowsonJan K, Imrie K, Myers R, Adams G, Ding K, et al: Gemcitabine, dexamethasone, and cisplatin in patients with recurrent or refractory aggressive histology B-cell non-Hodgkin lymphoma: A Phase II study by the national cancer institute of Canada clinical trials group (NCIC-CTG). Cancer. 101:1835–1842. 2004. View Article : Google Scholar : PubMed/NCBI

Related Articles

  • Abstract
  • View
  • Download
  • Twitter
Copy and paste a formatted citation
Spandidos Publications style
Zhang L, Lin Q, Zhang L, Dong L and Li Y: Primary skeletal muscle diffuse large B cell lymphoma: A case report and review of the literature. Oncol Lett 10: 2156-2160, 2015.
APA
Zhang, L., Lin, Q., Zhang, L., Dong, L., & Li, Y. (2015). Primary skeletal muscle diffuse large B cell lymphoma: A case report and review of the literature. Oncology Letters, 10, 2156-2160. https://doi.org/10.3892/ol.2015.3505
MLA
Zhang, L., Lin, Q., Zhang, L., Dong, L., Li, Y."Primary skeletal muscle diffuse large B cell lymphoma: A case report and review of the literature". Oncology Letters 10.4 (2015): 2156-2160.
Chicago
Zhang, L., Lin, Q., Zhang, L., Dong, L., Li, Y."Primary skeletal muscle diffuse large B cell lymphoma: A case report and review of the literature". Oncology Letters 10, no. 4 (2015): 2156-2160. https://doi.org/10.3892/ol.2015.3505
Copy and paste a formatted citation
x
Spandidos Publications style
Zhang L, Lin Q, Zhang L, Dong L and Li Y: Primary skeletal muscle diffuse large B cell lymphoma: A case report and review of the literature. Oncol Lett 10: 2156-2160, 2015.
APA
Zhang, L., Lin, Q., Zhang, L., Dong, L., & Li, Y. (2015). Primary skeletal muscle diffuse large B cell lymphoma: A case report and review of the literature. Oncology Letters, 10, 2156-2160. https://doi.org/10.3892/ol.2015.3505
MLA
Zhang, L., Lin, Q., Zhang, L., Dong, L., Li, Y."Primary skeletal muscle diffuse large B cell lymphoma: A case report and review of the literature". Oncology Letters 10.4 (2015): 2156-2160.
Chicago
Zhang, L., Lin, Q., Zhang, L., Dong, L., Li, Y."Primary skeletal muscle diffuse large B cell lymphoma: A case report and review of the literature". Oncology Letters 10, no. 4 (2015): 2156-2160. https://doi.org/10.3892/ol.2015.3505
Follow us
  • Twitter
  • LinkedIn
  • Facebook
About
  • Spandidos Publications
  • Careers
  • Cookie Policy
  • Privacy Policy
How can we help?
  • Help
  • Live Chat
  • Contact
  • Email to our Support Team