Radiological and clinical results following high-dose intensity-modulated radiotherapy in recurrent craniopharyngioma: A case report

Pierro,Antonio; Cilla,Savino; Picardi,Vincenzo; Ferro,Marica; Macchia,Gabriella; Deodato,Francesco; Buwenge,Milly; Sallustio,Giuseppina; Morganti,Alessio  G.

doi:10.3892/ol.2015.3514

October-2015 Volume 10 Issue 4

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October-2015 Volume 10 Issue 4

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Case Report

Radiological and clinical results following high-dose intensity-modulated radiotherapy in recurrent craniopharyngioma: A case report

Authors:
- Antonio Pierro
- Savino Cilla
- Vincenzo Picardi
- Marica Ferro
- Gabriella Macchia
- Francesco Deodato
- Milly Buwenge
- Giuseppina Sallustio
- Alessio G. Morganti
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Affiliations: Radiology Unit, Fondazione di Ricerca e Cura ‘Giovanni Paolo II’, Università Cattolica del Sacro Cuore, Campobasso 86100, Italy, Medical Physics Unit, Fondazione di Ricerca e Cura ‘Giovanni Paolo II’, Università Cattolica del Sacro Cuore, Campobasso 86100, Italy, Radiation Oncology Unit, Fondazione di Ricerca e Cura ‘Giovanni Paolo II’, Università Cattolica del Sacro Cuore, Campobasso 86100, Italy
Pages: 2491-2494
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Published online on: July 20, 2015

https://doi.org/10.3892/ol.2015.3514
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Abstract

Craniopharyngiomas (CPs) are rare benign suprasellar tumors. The standard treatment for CP is complete surgical resection or partial resection followed by adjuvant radiotherapy (RT). Adjuvant RT is typically administered at a total dose of 54 Gy with 1.8 Gy/fraction. The current study reported the case of a young patient affected by recurrent craniopharyngioma, who was treated with irradiation subsequent to several surgical resections. Image fusion and intensity‑modulated radiation therapy techniques were employed to deliver a high total dose (63 Gy with 2.1 Gy/fraction) with no severe acute toxicities recorded. At the 6‑year follow‑up, no radiological or clinical signs of disease progression or late sequelae were observed.

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Journals

International Journal of Molecular Medicine

International Journal of Oncology

Molecular Medicine Reports

Oncology Reports

Experimental and Therapeutic Medicine

Oncology Letters

Biomedical Reports

Molecular and Clinical Oncology

World Academy of Sciences Journal

International Journal of Functional Nutrition

International Journal of Epigenetics

Medicine International

Radiological and clinical results following high-dose intensity-modulated radiotherapy in recurrent craniopharyngioma: A case report

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