Surgical treatment of primary cardiac tumors in children: Experience of a single institute

Fan,Chengming; Gao,Zibo; Yin,Ni; Yang,Jinfu

doi:10.3892/ol.2015.3529

October-2015 Volume 10 Issue 4

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October-2015 Volume 10 Issue 4

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Article Open Access

Surgical treatment of primary cardiac tumors in children: Experience of a single institute

Authors:
- Chengming Fan
- Zibo Gao
- Ni Yin
- Jinfu Yang
View Affiliations / Copyright

Affiliations: Department of Cardiothoracic Surgery, The Second Xiangya Hospital, Central South University, Changsha, Hunan 410011, P.R. China

Copyright: © Fan et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
Pages: 2071-2074
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Published online on: July 23, 2015

https://doi.org/10.3892/ol.2015.3529
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Abstract

In order to review the surgical experience of a single institute with regard to the treatment of primary cardiac tumors, data was collected on patients with a histopathological diagnosis of a primary cardiac tumor (with the exception of myxoma) in a retrospective analysis of those treated between 2004 and 2013. In total, 11 patients were identified, with a mean age at diagnosis of 23 months and a mean weight of 13 kg. The most frequent cause of referral was a cardiac murmur and the most frequent cardiac tumor was rhabdomyoma (5 cases), followed by fibroma (3 cases), angiofibroma (2 cases) and fibrosarcoma (1 case). Surgical removal of the tumor was performed in all patients due to the respective clinical symptoms. A subtotal resection was performed in a single patient (with angiofibroma invading the aortic root, superior vena cava and sinus node) due to financial constraints. This patient succumbed to tumor invasion 2 years later. Another of the patients (pericardial fibrosarcoma) succumbed 1 year after the total resection, as they were unable to undergo a repeat surgery for the relapsed tumor due to financial inadequacy. The remaining 9 patients have survived in good condition during the 1‑6 year follow‑up. Surgery is the preferred treatment for patients with symptomatic primary cardiac tumors, and has good early‑ and long‑term outcomes. However, due to the current health care system inadequacies in China, certain parents cannot afford the medical expenses, thus, more comprehensive social security and medical insurance may require consideration.

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1	Paramés F, Freitas I, Martins JD, Trigo C and Pinto MF: Cardiac tumors: The 17-year experience of pediatric cardiology department. Rev Port Cardiol. 28:929–940. 2009.(In Portuguese). PubMed/NCBI
2	Tao TY, Yahyavi-Firouz-Abadi N, Singh GK and Bhalla S: Pediatric cardiac tumors: Clinical and imaging features. Radiographics. 34:1031–1046. 2014. View Article : Google Scholar : PubMed/NCBI
3	Gazit AZ, Singh GK, Shumway J, Johnson MC and Ludomirsky A: Fetal cardiac rhabdomyoma: A sheep or a wolf? J Matern Fetal Neonatal Med. 20:343–348. 2007. View Article : Google Scholar : PubMed/NCBI
4	Bielefeld KJ and Moller JH: Cardiac tumors in infants and children: Study of 120 operated patients. Pediatr Cardiol. 34:125–128. 2013. View Article : Google Scholar : PubMed/NCBI
5	Habertheuer A, Laufer G, Wiedemann D, Andreas M, Ehrlich M, Rath C and Kocher A: Primary cardiac tumors on the verge of oblivion: A European experience over 15 years. J Cardiothorac Surg. 10:562015. View Article : Google Scholar : PubMed/NCBI
6	Elbardissi AW, Dearani JA, Daly RC, Mullany CJ, Orszulak TA, Puga FJ and Schaff HV: Survival after resection of primary cardiac tumors: A 48-year experience. Circulation. 118 (Suppl 14):S7–S15. 2008. View Article : Google Scholar : PubMed/NCBI
7	Bakaeen FG, Reardon MJ, Coselli JS, Miller CC, Howell JF, Lawrie GM, Espada R, Ramchandani MK, Noon GP, Weilbaecher DG and DeBakey ME: Surgical outcome in 85 patients with primary cardiac tumors. Am J Surg. 186:641–647. 2003. View Article : Google Scholar : PubMed/NCBI
8	Issa OM, Reyna J, Santana O, DeBeer S, LaPietra A and Lamelas J: Cardiac angiofibroma: A rare primary cardiac tumor. J Card Surg. 28:404–405. 2013. View Article : Google Scholar : PubMed/NCBI
9	Lagrotteria DD, Tsang B, Elavathil LJ and Tomlinson CW: A case of primary malignant pericardial mesothelioma. Can J Cardiol. 21:185–187. 2005.PubMed/NCBI
10	NeragiMiandoab S, Kim J and Vlahakes GJ: Malignant tumours of the heart: A review of tumour type, diagnosis and therapy. Clin Oncol (R Coll Radiol). 19:748–756. 2007. View Article : Google Scholar : PubMed/NCBI
11	Wang HH: China's new health department: Progress and priorities. Lancet. 384:733–734. 2014. View Article : Google Scholar : PubMed/NCBI

Journals

International Journal of Molecular Medicine

International Journal of Oncology

Molecular Medicine Reports

Oncology Reports

Experimental and Therapeutic Medicine

Oncology Letters

Biomedical Reports

Molecular and Clinical Oncology

World Academy of Sciences Journal

International Journal of Functional Nutrition

International Journal of Epigenetics

Medicine International

Surgical treatment of primary cardiac tumors in children: Experience of a single institute

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