|
1
|
BlancoAparicio C, Renner O, Leal JF and
Carnero A: PTEN, more than the AKT pathway. Carcinogenesis.
28:1379–1386. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Carnero A, BlancoAparicio C, Renner O,
Link W and Leal JF: The PTEN/PI3K/AKT signalling pathway in cancer,
therapeutic implications. Curr Cancer Drug Targets. 8:187–198.
2008. View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Hou W, Liu J, Chen P, Wang H, Ye BC and
Qiang F: Mutation analysis of key genes in RAS/RAF and PI3K/PTEN
pathways in Chinese patients with hepatocellular carcinoma. Oncol
Lett. 8:1249–1254. 2014.PubMed/NCBI
|
|
4
|
Kechagioglou P, Papi RM, Provatopoulou X,
Kalogera E, Papadimitriou E, Grigoropoulos P, Nonni A, Zografos G,
Kyriakidis DA and Gounaris A: Tumor suppressor PTEN in breast
cancer: Heterozygosity, mutations and protein expression.
Anticancer Res. 34:1387–1400. 2014.PubMed/NCBI
|
|
5
|
Appin CL, Gao J, Chisolm C, Torian M,
Alexis D, Vincentelli C, Schniederjan MJ, Hadjipanayis C, Olson JJ,
Hunter S, et al: Glioblastoma with oligodendroglioma component
(GBM-O): Molecular genetic and clinical characteristics. Brain
Pathol. 23:454–461. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Reifenberger G and Collins VP: Pathology
and molecular genetics of astrocytic gliomas. J Mol Med Berl.
82:656–670. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Thakkar JP, Dolecek TA, Horbinski C,
Ostrom QT, Lightner DD, BarnholtzSloan JS and Villano JL:
Epidemiologic and molecular prognostic review of glioblastoma.
Cancer Epidemiol Biomarkers Prev. 23:1985–1996. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Qin J and Xu Q: Functions and application
of exosomes. Acta Pol Pharm. 71:537–543. 2014.PubMed/NCBI
|
|
9
|
Yan K, Yang K and Rich JN: The evolving
landscape of glioblastoma stem cells. Curr Opin Neurol. 26:701–707.
2013. View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Dahlrot RH, Hansen S, Jensen SS, Schrøder
HD, Hjelmborg J and Kristensen BW: Clinical value of CD133 and
nestin in patients with glioma: A population-based study. Int J
Clin Exp Pathol. 7:3739–3751. 2014.PubMed/NCBI
|
|
11
|
Kim SH, Kwon CH and Nakano I:
Detoxification of oxidative stress in glioma stem cells: Mechanism,
clinical relevance, and therapeutic development. J Neurosci Res.
92:1419–1424. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Hide T, Takezaki T, Nakamura H, Kuratsu J
and Kondo T: Brain tumor stem cells as research and treatment
targets. Brain Tumor Pathol. 25:67–72. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Sasaki A, Nakajo T, Tsunoda Y, Yamamoti G,
Kobayashi Y, Tsuji M, Udaka Y, Mizutani T and Oguchi K: Gene
analysis and dynamics of tumor stem cells in human glioblastoma
cells after radiation. Hum Cell. 26:73–79. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Lv S, Teugels E, Sadones J, De Brakeleer
S, Duerinck J, Du Four S, Michotte A, De Grève J and Neyns B:
Correlation of EGFR, IDH1 and PTEN status with the outcome of
patients with recurrent glioblastoma treated in a phase II clinical
trial with the EGFR-blocking monoclonal antibody cetuximab. Int J
Oncol. 41:1029–1035. 2012.PubMed/NCBI
|
|
15
|
Stechishin OD, Luchman HA, Ruan Y, Blough
MD, Nguyen SA, Kelly JJ, Caimcross JG and Weiss S: On-target
JAK2/STAT3 inhibition slows disease progression in orthotopic
xenografts of human glioblastoma brain tumor stem cells. Neuro
Oncol. 15:198–207. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Xie Q, Yan Y, Huang Z, Zhong X and Huang
L: MicroRNA-221 targeting PI3-K/Akt signaling axis induces cell
proliferation and BCNU resistance in human glioblastoma.
Neuropathology. 34:455–464. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Li W, Guo F, Wang P, Hong S and Zhang C:
miR-221/222 confers radioresistance in glioblastoma cells through
activating Akt independent of PTEN status. Curr Mol Med.
14:185–195. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Chung JH and Eng C: Nuclear-cytoplasmic
partitioning of phosphatase and tensin homologue deleted on
chromosome 10 (PTEN) differentially regulates the cell cycle and
apoptosis. Cancer Res. 65:8096–8100. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Tagawa H, Ikeda S and Sawada K: Role of
microRNA in the pathogenesis of malignant lymphoma. Cancer Sci.
104:801–809. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Rao E, Jiang C, Ji M, Huang X, Iqbal J,
Lenz G, Wright G, Staudt LM, Zhao Y, McKeithan TW, et al: The
miRNA-17-92 cluster mediates chemoresistance and enhances tumor
growth in mantle cell lymphoma via PI3K/AKT pathway activation.
Leukemia. 26:1064–1072. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Namløs HM, Meza-Zepeda LA, Barøy T,
Østensen IH, Kresse SH, Kuijjer ML, Serra M, Bürger H,
Cleton-Jansen AM and Myklebost O: Modulation of the osteosarcoma
expression phenotype by microRNAs. PLoS One. 7:e480862012.
View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Yamanaka Y, Tagawa H, Takahashi N,
Watanabe A, Guo YM, Iwamoto K, Yamashita J, Saitoh H, Kameoka Y,
Shimizu N, et al: Aberrant overexpression of microRNAs activate AKT
signaling via down-regulation of tumor suppressors in natural
killer-cell lymphoma/leukemia. Blood. 114:3265–3275. 2009.
View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Ristorcelli E, Beraud E, Verrando P,
Villard C, Lafitte D, Sbarra V, Lombardo D and Verine A: Human
tumor nanoparticles induce apoptosis of pancreatic cancer cells.
FASEB J. 22:3358–3369. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Asano T, Fujishiro M, Kushiyama A, Nakatsu
Y, Yoneda M, Kamata H and Sakoda H: Role of phosphatidylinositol
3-kinase activation on insulin action and its alteration in
diabetic conditions. Biol Pharm Bull. 30:1610–1616. 2007.
View Article : Google Scholar : PubMed/NCBI
|
|
25
|
Chung JH, GinnPease ME and Eng C:
Phosphatase and tensin homologue deleted on chromosome 10 (PTEN)
has nuclear localization signal-like sequences for nuclear import
mediated by major vault protein. Cancer Res. 65:4108–4116. 2005.
View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Liu JL, Sheng X, Hortobagyi ZK, Mao Z,
Gallick GE and Yung WK: Nuclear PTEN-mediated growth suppression is
independent of Akt down-regulation. Mol Cell Biol. 25:6211–6224.
2005. View Article : Google Scholar : PubMed/NCBI
|
|
27
|
Morales LD, Casillas Pavón EA, Shin JW,
Garcia A, Capetillo M, Kim DJ and Lieman JH: Protein tyrosine
phosphatases PTP-1B, SHP-2, and PTEN facilitate Rb/E2F-associated
apoptotic signaling. PLoS One. 9:e971042014. View Article : Google Scholar : PubMed/NCBI
|
