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Article

Low‑dose interleukin‑8 induces the adhesion, migration and invasion of the gastric cancer SGC‑7901 cell line

  • Authors:
    • Jun Shi
    • Pin‑Kang Wei
  • View Affiliations / Copyright

    Affiliations: Department of Traditional Chinese Medicine, Shanghai Changzheng Hospital, The Second Military Medical University, Shanghai 200003, P.R. China
  • Pages: 2871-2877
    |
    Published online on: August 25, 2015
       https://doi.org/10.3892/ol.2015.3641
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Abstract

Interleukin‑8 (IL‑8), an important inflammatory cytokine, is strongly associated with gastric cancer development and metastasis. High‑dose (>1 ng/ml) IL‑8 has been revealed to promote the adhesion, migration and invasion of human gastric cancer SGC‑7901 cells in a dose‑dependent manner. However, the IL‑8 level produced by gastric cells is marginal, at even less than 1 ng/ml. It is unclear whether low‑dose IL‑8 also induces these capacities. In the present study, the effect of low‑dose IL‑8 on the adhesion, migration and invasion of the SGC‑7901 cell line and the underlying molecular mechanism with regard to cluster of differentiation 44 (CD44) were investigated. The SGC‑7901 cells were exposed to various concentrations of IL‑8 (0, 0.2, 0.5, 0.8 and 1 ng/ml) in vitro. The adhesion of the SGC‑7901 cells to fibronectin, an extracellular matrix component, was then detected by cell counting kit 8 assay. Migration and invasion abilities were evaluated by wound scratch and Transwell chamber assays. In addition, protein and mRNA levels of CD44 were measured using immunofluorescence and western blotting, and quantitative polymerase chain reaction, respectively, in cells cultured for 72 h. Following the exposure of the SGC‑7901 cells to the various low doses of IL‑8, the cell adhesion, migration and invasion capacities were promoted by IL‑8, but not in a significant dose‑dependent manner. Low‑dose IL‑8 upregulated the protein and mRNA expression of CD44. In conclusion, low‑dose IL‑8 potently induces the adhesion, migration and invasion of SGC‑7901 cells, and the regulation of CD44 expression is one of the potential molecular mechanisms involved.
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View References

1 

Parkin DM, Bray F, Ferlay J and Pisani P: Global cancer statistics, 2002. CA Cancer J Clin. 55:74–108. 2005. View Article : Google Scholar : PubMed/NCBI

2 

Goubran HA, Kotb RR, Stakiw J, Emara ME and Burnouf T: Regulation of tumor growth and metastasis: The role of tumor microenvironment. Cancer Growth Metastasis. 7:9–18. 2014. View Article : Google Scholar : PubMed/NCBI

3 

Araki S, Omori Y, Lyn D, Singh RK, Meinbach DM, Sandman Y, Lokeshwar VB and Lokeshwar BL: Interleukin-8 is a molecular determinant of androgen independence and progression in prostate cancer. Cancer Res. 67:6854–6862. 2007. View Article : Google Scholar : PubMed/NCBI

4 

Waugh DJ and Wilson C: The interleukin-8 pathway in cancer. Clin Cancer Res. 14:6735–6741. 2008. View Article : Google Scholar : PubMed/NCBI

5 

Harada A, Sekido N, Akahoshi T, Wada T, Mukaida N and Matsushima K: Essential involvement of interleukin-8 (IL-8) in acute inflammation. J Leukoc Biol. 56:559–564. 1994.PubMed/NCBI

6 

Raman D, Baugher PJ, Thu YM and Richmond A: Role of chemokines in tumor growth. Cancer Lett. 256:137–165. 2007. View Article : Google Scholar : PubMed/NCBI

7 

Xie K: Interleukin-8 and human cancer biology. Cytokine Growth Factor Rev. 12:375–391. 2001. View Article : Google Scholar : PubMed/NCBI

8 

Gabellini C, Trisciuoglio D, Desideri M, Candiloro A, Ragazzoni Y, Orlandi A, Zupi G and Del Bufalo D: Functional activity of CXCL8 receptors, CXCR1 and CXCR2, on human malignant melanoma progression. Eur J Cancer. 45:2618–2627. 2009. View Article : Google Scholar : PubMed/NCBI

9 

Kamohara H, Takahashi M, Ishiko T, Ogawa M and Baba H: Induction of interleukin-8 (CXCL-8) by tumor necrosis factor-alpha and leukemia inhibitory factor in pancreatic carcinoma cells: Impact of CXCL-8 as an autocrine growth factor. Int J Oncol. 31:627–632. 2007.PubMed/NCBI

10 

Itoh Y, Joh T, Tanida S, Sasaki M, Kataoka H, Itoh K, Oshima T, Ogasawara N, Togawa S, Wada T, et al: IL-8 promotes cell proliferation and migration through metalloproteinase-cleavage proHB-EGF in human colon carcinoma cells. Cytokine. 29:275–282. 2005.PubMed/NCBI

11 

Merritt WM, Lin YG, Spannuth WA, Fletcher MS, Kamat AA, Han LY, Landen CN, Jennings N, De Geest K, Langley RR, et al: Effect of interleukin-8 gene silencing with liposome-encapsulated small interfering RNA on ovarian cancer cell growth. J Natl Cancer Inst. 100:359–372. 2008. View Article : Google Scholar : PubMed/NCBI

12 

Ning Y, Manegold PC, Hong YK, Zhang W, Pohl A, Lurje G, Winder T, Yang D, Labonte MJ, Wilson PM, et al: Interleukin-8 is associated with proliferation, migration, angiogenesis and chemosensitivity in vitro and in vivo in colon cancer cell line models. Int J Cancer. 128:2038–2049. 2011. View Article : Google Scholar : PubMed/NCBI

13 

Matsuo Y, Ochi N, Sawai H, et al: CXCL8/IL-8 and CXCL12/SDF-1alpha co-operatively promote invasiveness and angiogenesis in pancreatic cancer. Int J Cancer. 124:853–861. 2009. View Article : Google Scholar : PubMed/NCBI

14 

Kitadai Y, Takahashi Y, Haruma K, Naka K, Sumii K, Yokozaki H, Yasui W, Mukaida N, Ohmoto Y, Kajiyama G, et al: Transfection of interleukin-8 increases angiogenesis and tumorigenesis of human gastric carcinoma cells in nude mice. Br J Cancer. 81:647–653. 1999. View Article : Google Scholar : PubMed/NCBI

15 

Chen JJ, Yao PL, Yuan A, Hong TM, Shun CT, Kuo ML, Lee YC and Yang PC: Up-regulation of tumor interleukin-8 expression by infiltrating macrophages: Its correlation with tumor angiogenesis and patient survival in non-small cell lung cancer. Clin Cancer Res. 9:729–737. 2003.PubMed/NCBI

16 

Ju D, Sun D, Xiu L, Meng X, Zhang C and Wei P: Interleukin-8 is associated with adhesion, migration and invasion in human gastric cancer SCG-7901 cells. Med Oncol. 29:91–99. 2012. View Article : Google Scholar : PubMed/NCBI

17 

Iwai M, Matsuda M and Iwai Y: Cloning of a cancer cell-producing hepatocyte growth factor, vascular endothelial growth factor and interleukin-8 from gastric cancer cells. Vitro Cell Dev Biol Anim. 39:288–290. 2003. View Article : Google Scholar

18 

Jin X, Zhu Z and Shi Y: Metastasis mechanism and gene/protein expression in gastric cancer with distant organs metastasis. Bull Cancer. 2014.((Epub ahead of print)). PubMed/NCBI

19 

Ferlay J, Shin HR, Bray F, Forman D, Mathers C and Parkin DM: Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008. Int J Cancer. 127:2893–2917. 2010. View Article : Google Scholar : PubMed/NCBI

20 

Deng JY and Liang H: Clinical significance of lymph node metastasis in gastric cancer. World J Gastroenterol. 20:3967–3975. 2014. View Article : Google Scholar : PubMed/NCBI

21 

Goubran HA, Kotb RR, Stakiw JI, Emara ME and Burnouf T: Regulation of tumor growth and metastasis: The role of tumor microenvironment. Cancer Growth Metastasis. 7:9–18. 2014. View Article : Google Scholar : PubMed/NCBI

22 

Martin TA, Mason MD and Jiang WG: Tight junctions in cancer metastasis. Front Biosci (Landmark Ed). 16:898–936. 2011. View Article : Google Scholar : PubMed/NCBI

23 

Campbell LM, Maxwell PJ and Waugh DJ: Rationale and means to target pro-inflammatory interleukin-8 (CXCL8) signaling in cancer. Pharmaceuticals (Basel). 6:929–959. 2013. View Article : Google Scholar : PubMed/NCBI

24 

Gabellini C, Trisciuoglio D, Desideri M, et al: Functional activity of CXCL8 receptors, CXCR1 and CXCR2, on human malignant melanoma progression. Eur J Cancer. 45:2618–2627. 2009. View Article : Google Scholar : PubMed/NCBI

25 

Christofakis EP, Miyazaki H, Rubink DS and Yeudall WA: Roles of CXCL8 in squamous cell carcinoma proliferation and migration. Oral Oncol. 44:920–926. 2008. View Article : Google Scholar : PubMed/NCBI

26 

Wu S, Shang H, Cui L, Zhang Z, Zhang Y, Li Y, Wu J, Li RK and Xie J: Targeted blockade of interleukin-8 abrogates its promotion of cervical cancer growth and metastasis. Mol Cell Biochem. 375:69–79. 2013.PubMed/NCBI

27 

Wang Y, Xu RC, Zhang XL, Niu XL, Qu Y, Li LZ and Meng XY: Interleukin-8 secretion by ovarian cancer cells increases anchorage-independent growth, proliferation, angiogenic potential, adhesion and invasion. Cytokine. 59:145–155. 2012. View Article : Google Scholar : PubMed/NCBI

28 

Luppi F, Longo AM, de Boer WI, Rabe KF and Hiemstra PS: Interleukin-8 stimulates cell proliferation in non-small cell lung cancer through epidermal growth factor receptor transactivation. Lung Cancer. 56:25–33. 2007. View Article : Google Scholar : PubMed/NCBI

29 

Baggiolini M and Clark-Lewis I: Interleukin-8, a chemotactic and inflammatory cytokine. FEBS Lett. 307:97–101. 1992. View Article : Google Scholar : PubMed/NCBI

30 

Zhu YM and Woll PJ: Mitogenic effects of interleukin-8/CXCL8 on cancer cells. Future Oncol. 1:699–704. 2005. View Article : Google Scholar : PubMed/NCBI

31 

Takagi A, Kamiya S, Koga Y, Ohta U, Kobayashi H, Shirai T, Harasawa S and Miwa T: Analysis of interleukin-8 secretion induced by Helicobacter pylori from the gastric epithelial cell line MKN45: A mechanism independent of the intensity of cytotoxicity. J Gastroenterol Hepatol. 12:368–372. 1997. View Article : Google Scholar : PubMed/NCBI

32 

Kitadai Y, Haruma K, Mukaida N, Ohmoto Y, Matsutani N, Yasui W, Yamamoto S, Sumii K, Kajiyama G, Fidler IJ and Tahara E: Regulation of disease-progression genes in human gastric carcinoma cells by interleukin 8. Clin Cancer Res. 6:2735–2740. 2000.PubMed/NCBI

33 

Kitadai Y, Haruma K, Sumii K, Yamamoto S, Ue T, Yokozaki H, Yasui W, Ohmoto Y, Kajiyama G, Fidler IJ and Tahara E: Expression of interleukin-8 correlates with vascularity in human gastric carcinomas. Am J Pathol. 152:93–100. 1998.PubMed/NCBI

34 

Kido S, Kitadai Y, Hattori N, Haruma K, Kido T, Ohta M, Tanaka S, Yoshihara M, Sumii K, Ohmoto Y and Chayama K: Interleukin 8 and vascular endothelial growth factor-prognostic factors in human gastric carcinomas? Eur J Cancer. 37:1482–1487. 2001. View Article : Google Scholar : PubMed/NCBI

35 

Kuai WX, Wang Q, Yang XZ, Zhao Y, Yu R and Tang XJ: Interleukin-8 associates with adhesion, migration, invasion and chemosensitivity of human gastric cancer cells. World J Gastroenterol. 18:979–985. 2012. View Article : Google Scholar : PubMed/NCBI

36 

Picker LJ, Nakache M and Butcher EC: Monoclonal antibodies to human lymphocyte homing receptors define a novel class of adhesion molecules on diverse cell types. J Cell Biol. 109:927–937. 1989. View Article : Google Scholar : PubMed/NCBI

37 

Aruffo AI, Stamenkovic I, Melnick M, Underhill CB and Seed B: CD44 is the principal cell surface receptor for hyaluronate. Cell. 61:1303–1313. 1990. View Article : Google Scholar : PubMed/NCBI

38 

Haynes BF, Telen MJ, Hale LP and Denning SM: CD44 - a molecule involved in leukocyte adherence and T-cell activation. Immunol Today. 10:423–428. 1989. View Article : Google Scholar : PubMed/NCBI

39 

Hsieh HF, Yu JC, Ho LI, Chiu SC and Harn HJ: Molecular studies into the role of CD44 variants in metastasis in gastric cancer. Mol Pathol. 52:25–28. 1999. View Article : Google Scholar : PubMed/NCBI

40 

Abbaszadegan MR, Moaven O, Sima HR, Ghafarzadegan K, A'rabi A, Forghani MN, Raziee HR, Mashhadinejad A, Jafarzadeh M, Esmaili-Shandiz E and Dadkhah E: p16 promoter hypermethylation: A useful serum marker for early detection of gastric cancer. World J Gastroenterol. 14:2055–2060. 2008. View Article : Google Scholar : PubMed/NCBI

41 

Zavrides HN, Zizi-Sermpetzoglou A, Panousopoulos D, Athanasas G, Elemenoglou I and Peros G: Prognostic evaluation of CD44 expression in correlation with bcl-2 and p53 in colorectal cancer. Folia Histochem Cytobiol. 43:31–36. 2005.PubMed/NCBI

42 

Wang DR, Chen GY, Liu XL, Miao Y, Xia JG, Zhu LH and Tang D: CD44v6 in peripheral blood and bone marrow of patients with gastric cancer as micro-metastasis. World J Gastroenterol. 12:36–42. 2006.PubMed/NCBI

43 

Jothy S: CD44 and its partners in metastasis. Clin Exp Metastasis. 20:195–201. 2003. View Article : Google Scholar : PubMed/NCBI

44 

Ghaffarzadehgan K, Jafarzadeh M, Raziee HR, Sima HR, Esmaili-Shandiz E, Hosseinnezhad H, Taghizadeh-Kermani A, Moaven O and Bahrani M: Expression of cell adhesion molecule CD44 in gastric adenocarcinoma and its prognostic importance. World J Gastroenterol. 14:6376–6381. 2008. View Article : Google Scholar : PubMed/NCBI

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Copy and paste a formatted citation
Spandidos Publications style
Shi J and Wei PK: Low‑dose interleukin‑8 induces the adhesion, migration and invasion of the gastric cancer SGC‑7901 cell line. Oncol Lett 10: 2871-2877, 2015.
APA
Shi, J., & Wei, P. (2015). Low‑dose interleukin‑8 induces the adhesion, migration and invasion of the gastric cancer SGC‑7901 cell line. Oncology Letters, 10, 2871-2877. https://doi.org/10.3892/ol.2015.3641
MLA
Shi, J., Wei, P."Low‑dose interleukin‑8 induces the adhesion, migration and invasion of the gastric cancer SGC‑7901 cell line". Oncology Letters 10.5 (2015): 2871-2877.
Chicago
Shi, J., Wei, P."Low‑dose interleukin‑8 induces the adhesion, migration and invasion of the gastric cancer SGC‑7901 cell line". Oncology Letters 10, no. 5 (2015): 2871-2877. https://doi.org/10.3892/ol.2015.3641
Copy and paste a formatted citation
x
Spandidos Publications style
Shi J and Wei PK: Low‑dose interleukin‑8 induces the adhesion, migration and invasion of the gastric cancer SGC‑7901 cell line. Oncol Lett 10: 2871-2877, 2015.
APA
Shi, J., & Wei, P. (2015). Low‑dose interleukin‑8 induces the adhesion, migration and invasion of the gastric cancer SGC‑7901 cell line. Oncology Letters, 10, 2871-2877. https://doi.org/10.3892/ol.2015.3641
MLA
Shi, J., Wei, P."Low‑dose interleukin‑8 induces the adhesion, migration and invasion of the gastric cancer SGC‑7901 cell line". Oncology Letters 10.5 (2015): 2871-2877.
Chicago
Shi, J., Wei, P."Low‑dose interleukin‑8 induces the adhesion, migration and invasion of the gastric cancer SGC‑7901 cell line". Oncology Letters 10, no. 5 (2015): 2871-2877. https://doi.org/10.3892/ol.2015.3641
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