Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Oncology Letters
      • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Biomedical Reports
      • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • Information for Authors
    • Information for Reviewers
    • Information for Librarians
    • Information for Advertisers
    • Conferences
  • Language Editing
Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • For Authors
    • For Reviewers
    • For Librarians
    • For Advertisers
    • Conferences
  • Language Editing
Login Register Submit
  • This site uses cookies

  • You can change your cookie settings at any time by following the instructions in our Cookie Policy. To find out more, you may read our Privacy Policy.

    I agree
Search articles by DOI, keyword, author or affiliation
Search
Advanced Search
presentation
Oncology Letters
Join Editorial Board Propose a Special Issue
Print ISSN: 1792-1074 Online ISSN: 1792-1082
Journal Cover
November-2015 Volume 10 Issue 5

Full Size Image

Sign up for eToc alerts
Recommend to Library

Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

Journal Cover
November-2015 Volume 10 Issue 5

Full Size Image

Sign up for eToc alerts
Recommend to Library

  • Article
  • Citations
    • Cite This Article
    • Download Citation
    • Create Citation Alert
    • Remove Citation Alert
    • Cited By
  • Similar Articles
    • Related Articles (in Spandidos Publications)
    • Similar Articles (Google Scholar)
    • Similar Articles (PubMed)
  • Download PDF
  • Download XML
  • View XML
Case Report

Leptomeningeal metastasis from early glottic laryngeal cancer: A case report

  • Authors:
    • Zhenyu Pan
    • Guozi Yang
    • Limei Qu
    • Tingting Yuan
    • Xiaochuan Pang
    • Yongxiang Wang
    • Weiyan Shi
    • Lihua Dong

  • View Affiliations / Copyright

    Affiliations: Department of Radiotherapy, Norman Bethune First Hospital of Jilin University, Changchun, Jilin 130021, P.R. China, Department of Pathology, Norman Bethune First Hospital of Jilin University, Changchun, Jilin 130021, P.R. China, Department of Radiology, Norman Bethune First Hospital of Jilin University, Changchun, Jilin 130021, P.R. China, Department of Clinical Laboratory, Norman Bethune First Hospital of Jilin University, Changchun, Jilin 130021, P.R. China
  • Pages: 2915-2918
    |
    Published online on: August 25, 2015
       https://doi.org/10.3892/ol.2015.3643
  • Expand metrics +
Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )
Metrics: Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )
Cited By (CrossRef): 0 citations Loading Articles...

This article is mentioned in:



Abstract

The present study reports the case of a 53‑year‑old man with leptomeningeal metastasis from early glottic laryngeal cancer. The patient had been diagnosed with squamous cell carcinoma of the glottic larynx 9 years previously. The current symptoms included a recurring headache that had persisted for 1 month and vomiting for 1 week. A magnetic resonance imaging scan of the head revealed multiple enhancing lesions in the brain and multiple line‑like enhancements in the brain fold. Computed tomography scans of the head, neck, chest and abdomen showed no nodular lesions. Cytological examination of the cerebral spinal fluid (CSF) revealed malignant cells with a scattered distribution pattern. The patient received intra‑CSF methotrexate chemotherapy concurrent with whole‑brain radiotherapy, which relieved the neurological symptoms. To the best of our knowledge, this is the first case of cytologically‑confirmed LM from early glottic laryngeal cancer.
View Figures

Figure 1

Figure 2

Figure 3

Figure 4

View References

1 

Spector ME, Chinn SB, Rosko AJ, Worden FP, Ward PD, Divi V, McLean SA, Moyer JS, Prince ME, Wolf GT, et al: Diagnostic modalities for distant metastasis in head and neck squamous cell carcinoma: Are we changing life expectancy? Laryngoscope. 122:1507–1511. 2012. View Article : Google Scholar : PubMed/NCBI

2 

de Araújo Neto VJ Furtado, Cernea CR, Dedivitis R Aparecido, de Araújo Filho VJ Furtado, Palazzo J Fabiano and Brandão L Garcia: Cervical metastasis on level IV in laryngeal cancer. Acta Otorhinolaryngol Ital. 34:15–18. 2014.PubMed/NCBI

3 

Gallegos JF, Fuentes A, Arroyo C, Minauro G, Hernández M and Arias H: Laryngeal function as node metastasis predictor in patients with cancer of the larynx. Gac Med Mex. 146:175–178. 2010.PubMed/NCBI

4 

Le Rhun E, Taillibert S and Chamberlain MC: Carcinomatous meningitis: Leptomeningeal metastases in solid tumors. Surg Neurol Int. 4(Suppl 4): S265–S288. 2013.PubMed/NCBI

5 

Redman BG, Tapazoglou E and Al-Sarraf M: Meningeal carcinomatosis in head and neck cancer. Report of six cases and review of the literature. Cancer. 58:2656–2661. 1986. View Article : Google Scholar : PubMed/NCBI

6 

Thompson SR, Veness MJ, Morgan GJ, Shannon J and Kench JG: Leptomeningeal carcinomatosis from squamous cell carcinoma of the supraglottic larynx. Australas Radiol. 47:325–330. 2003. View Article : Google Scholar : PubMed/NCBI

7 

Banerjee TK and Gottschalk PG: Unusual manifestations of multiple cranial nerve palsies and mandibular metastasis in a patient with squamous cell carcinoma of the lip. Cancer. 53:346–348. 1984. View Article : Google Scholar : PubMed/NCBI

8 

Biswal BM, Goyal M, Prasad RR, Lal P, Sharma R, Mohanti BK and Khader J: Leptomeningeal carcinomatosis from carcinoma of the palatine tonsil. Australas Radiol. 42:66–68. 1998. View Article : Google Scholar : PubMed/NCBI

9 

Pfister DG, Spencer S, Brizel DM, Burtness B, Busse PM, Caudell JJ, Cmelak AJ, Colevas AD, Dunphy F, Eisele DW, et al: Head and neck cancers, version 2.2014. Clinical practice guidelines in oncology. J Natl Compr Canc Netw. 12:1454–1487. 2014.PubMed/NCBI

10 

Teasdale G and Jennett B: Assessment of coma and impaired consciousness. A practical scale. Lancet. 2:81–84. 1974. View Article : Google Scholar : PubMed/NCBI

11 

Karnofsky DA and Burchenal JH: The clinical evaluation of chemotherapeutic agents in cancer. Evaluation of Chemotherapeutic Agents. MacLeod CM: Columbia University Press. (Columbia). 1961949.

12 

Wenig BM: Squamous cell carcinoma of the upper aerodigestive tract: Precursors and problematic variants. Mod Pathol. 15:229–254. 2002. View Article : Google Scholar : PubMed/NCBI

13 

Igissinov N, Zatoskikh V, Moore MA, Igissinov S, Toulebaeyev R, Mustafina M, Valieva S, Aldiyarova G, Bukeyeva Z and Venglovskiy A: Epidemiological evaluation of laryngeal cancer incidence in Kazakhstan for the years 1999–2009. Asian Pac J Cancer Prev. 14:3969–3974. 2013. View Article : Google Scholar : PubMed/NCBI

14 

Pan Z, Yang G, Yuan T, Pang X, Wang Y, Qu L and Dong L: Leptomeningeal metastasis from hepatocellular carcinoma with other unusual metastases: A case report. BMC Cancer. 14:3992014. View Article : Google Scholar : PubMed/NCBI

Related Articles

  • Abstract
  • View
  • Download
  • Twitter
Copy and paste a formatted citation
Spandidos Publications style
Pan Z, Yang G, Qu L, Yuan T, Pang X, Wang Y, Shi W and Dong L: Leptomeningeal metastasis from early glottic laryngeal cancer: A case report. Oncol Lett 10: 2915-2918, 2015.
APA
Pan, Z., Yang, G., Qu, L., Yuan, T., Pang, X., Wang, Y. ... Dong, L. (2015). Leptomeningeal metastasis from early glottic laryngeal cancer: A case report. Oncology Letters, 10, 2915-2918. https://doi.org/10.3892/ol.2015.3643
MLA
Pan, Z., Yang, G., Qu, L., Yuan, T., Pang, X., Wang, Y., Shi, W., Dong, L."Leptomeningeal metastasis from early glottic laryngeal cancer: A case report". Oncology Letters 10.5 (2015): 2915-2918.
Chicago
Pan, Z., Yang, G., Qu, L., Yuan, T., Pang, X., Wang, Y., Shi, W., Dong, L."Leptomeningeal metastasis from early glottic laryngeal cancer: A case report". Oncology Letters 10, no. 5 (2015): 2915-2918. https://doi.org/10.3892/ol.2015.3643
Copy and paste a formatted citation
x
Spandidos Publications style
Pan Z, Yang G, Qu L, Yuan T, Pang X, Wang Y, Shi W and Dong L: Leptomeningeal metastasis from early glottic laryngeal cancer: A case report. Oncol Lett 10: 2915-2918, 2015.
APA
Pan, Z., Yang, G., Qu, L., Yuan, T., Pang, X., Wang, Y. ... Dong, L. (2015). Leptomeningeal metastasis from early glottic laryngeal cancer: A case report. Oncology Letters, 10, 2915-2918. https://doi.org/10.3892/ol.2015.3643
MLA
Pan, Z., Yang, G., Qu, L., Yuan, T., Pang, X., Wang, Y., Shi, W., Dong, L."Leptomeningeal metastasis from early glottic laryngeal cancer: A case report". Oncology Letters 10.5 (2015): 2915-2918.
Chicago
Pan, Z., Yang, G., Qu, L., Yuan, T., Pang, X., Wang, Y., Shi, W., Dong, L."Leptomeningeal metastasis from early glottic laryngeal cancer: A case report". Oncology Letters 10, no. 5 (2015): 2915-2918. https://doi.org/10.3892/ol.2015.3643
Follow us
  • Twitter
  • LinkedIn
  • Facebook
About
  • Spandidos Publications
  • Careers
  • Cookie Policy
  • Privacy Policy
How can we help?
  • Help
  • Live Chat
  • Contact
  • Email to our Support Team