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Article

Predictive role of preoperative hydronephrosis on poor pathological outcomes and prognosis in upper tract urothelial carcinoma patients: Experience from a nationwide high-volume center in China

  • Authors:
    • Zheng Zhang
    • Dong Fang
    • Xiaopeng Chen
    • Xuesong Li
    • Gengyan Xiong
    • Lei Zhang
    • Qun He
    • Liqun Zhou
  • View Affiliations / Copyright

    Affiliations: Department of Urology, Peking University First Hospital, Institute of Urology, Peking University, National Urological Cancer Center, Beijing 100034, P.R. China
  • Pages: 3113-3122
    |
    Published online on: August 28, 2015
       https://doi.org/10.3892/ol.2015.3653
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Abstract

To validate the predictive value of preoperative hydronephrosis (HN) with regard to clinicopathological outcome and prognosis in a large cohort of upper tract urothelial carcinoma (UTUC) patients, a retrospective analysis was conducted using the clinicopathological data of 520 consecutive patients treated between 2000 and 2010 at a nationwide high‑volume center in China. Preoperative computed tomography or magnetic resonance imaging scans were evaluated for the presence of ipsilateral HN, and the associations between HN and pathological outcomes, patient survival and urinary tract recurrences were assessed. Ipsilateral HN was present in 271 patients (52.1%). Preoperative HN was associated with advanced age (P=0.007), sessile tumor architecture (P<0.001), ureteral location (P<0.001), higher tumor stage (P<0.001) and higher histological grade (P=0.002). Univariate and multivariate analyses revealed that poorer cancer‑specific survival (CSS) and overall survival (OS) times were correlated with preoperative HN (P=0.004 and P=0.009, respectively). The 5‑year CSS and OS rates for patients with HN were 86.9 and 86.2%, respectively, compared to 93.3 and 91.9% for patients without HN. For patients with muscle‑invasive disease, HN remained a risk factor for poor CSS and OS (P=0.009 and P=0.012, respectively). No association was identified between HN and bladder recurrence (P=0.552) or the development of contralateral upper tract carcinoma (P=0.164). The findings indicated that preoperative HN is prevalent in UTUC. The presence of preoperative HN predicted poorer pathological outcomes and was a significant risk factor affecting survival. The evaluation of HN may be informative for decisions concerning surgical options, and the presence of HN should raise the possibility of employing an aggressive treatment approach.
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1 

Siegel R, Naishadham D and Jemal A: Cancer statistics, 2012. CA Cancer J Clin. 62:10–29. 2012. View Article : Google Scholar : PubMed/NCBI

2 

Pérez M Pérez-Utrilla, Bazán A Aguilera, Dorrego JM Alonso, et al: Simultaneous cystectomy and nephroureterectomy due to synchronous upper urinary tract tumors and invasive bladder cancer: Open and laparoscopic approaches. Curr Urol. 6:76–81. 2012. View Article : Google Scholar : PubMed/NCBI

3 

Cummings KB: Nephroureterectomy: Rationale in the management of transitional cell carcinoma of the upper urinary tract. Urol Clin North Am. 7:569–578. 1980.PubMed/NCBI

4 

McLaughlin JK, Silverman DT, Hsing AW, et al: Cigarette smoking and cancers of the renal pelvis and ureter. Cancer Res. 52:254–257. 1992.PubMed/NCBI

5 

Colin P, Koenig P, Ouzzane A, et al: Environmental factors involved in carcinogenesis of urothelial cell carcinomas of the upper urinary tract. BJU Int. 104:1436–1440. 2009. View Article : Google Scholar : PubMed/NCBI

6 

Cowan NC: CT urography for hematuria. Nat Rev Urol. 9:218–226. 2012. View Article : Google Scholar : PubMed/NCBI

7 

Sobin L, Gospodarowicz M and Wittekind C: Urological tumours. Renal pelvis and ureter. TNM Classification of Malignant Tumours (7th). Wiley-Blackwell. (Hoboken, NJ). 258–261. 2009.

8 

Rink M, Ehdaie B, Cha EK, et al: Bladder Cancer Research Consortium (BCRC); Upper Tract Urothelial Carcinoma Collaboration (UTUCC): Stage-specific impact of tumor location on oncologic outcomes in patients with upper and lower tract urothelial carcinoma following radical surgery. Eur Urol. 62:677–684. 2012. View Article : Google Scholar : PubMed/NCBI

9 

Cha EK, Shariat SF, Kormaksson M, et al: Predicting clinical outcomes after radical nephroureterectomy for upper tract urothelial carcinoma. Eur Urol. 61:818–825. 2012. View Article : Google Scholar : PubMed/NCBI

10 

Roupret M, Babjuk M, Comperat E, et al: European Association of Urology: European guidelines on upper tract urothelial carcinomas: 2013 update. Eur Urol. 63:1059–1071. 2013. View Article : Google Scholar : PubMed/NCBI

11 

Margulis V, Shariat SF, Matin SF, et al: Outcomes of radical nephroureterectomy: A series from the upper tract urothelial carcinoma collaboration. Cancer. 115:1224–1233. 2009. View Article : Google Scholar : PubMed/NCBI

12 

Gadzinski AJ, Roberts WW, Faerber GJ and Wolf JS Jr: Long-term outcomes of nephroureterectomy versus endoscopic management for upper tract urothelial carcinoma. J Urol. 183:2148–2153. 2010. View Article : Google Scholar : PubMed/NCBI

13 

Colin P, Ouzzane A, Pignot G, et al: Comparison of oncological outcomes after segmental ureterectomy or radical nephroureterectomy in urothelial carcinomas of the upper urinary tract: Results from a large French multicentre study. BJU Int. 110:1134–1141. 2012. View Article : Google Scholar : PubMed/NCBI

14 

Murphy DM, Zincke H and Furlow WL: Primary grade 1 transitional cell carcinoma of the renal pelvis and ureter. J Urol. 123:629–631. 1980.PubMed/NCBI

15 

Matin SF, Margulis V, Kamat A, et al: Incidence of downstaging and complete remission after neoadjuvant chemotherapy for high-risk upper tract transitional cell carcinoma. Cancer. 116:3127–3134. 2010. View Article : Google Scholar : PubMed/NCBI

16 

Youssef RF, Shariat SF, Lotan Y, et al: Upper urinary tract urothelial carcinoma with loco-regional nodal metastases: Insights from the upper tract urothelial carcinoma collaboration. BJU Int. 108:1286–1291. 2011. View Article : Google Scholar : PubMed/NCBI

17 

Ng CK, Shariat SF, Lucas SM, et al: Does the presence of hydronephrosis on preoperative axial CT imaging predict worse outcomes for patients undergoing nephroureterectomy for upper-tract urothelial carcinoma? Urol Oncol. 29:27–32. 2011. View Article : Google Scholar : PubMed/NCBI

18 

Divrik RT, Sahin A, Altok M, Unlu N and Zorlu F: The frequency of hydronephrosis at initial diagnosis and its effect on recurrence and progression in patients with superficial bladder cancer. J Urol. 178:802–806. 2007. View Article : Google Scholar : PubMed/NCBI

19 

Haleblian GE, Skinner EC, Dickinson MG, Lieskovsky G, Boyd SD and Skinner DG: Hydronephrosis as a prognostic indicator in bladder cancer patients. J Urol. 160:2011–2014. 1998. View Article : Google Scholar : PubMed/NCBI

20 

Bartsch GC, Kuefer R, Gschwend JE, de Petriconi R, Hautmann RE and Volkmer BG: Hydronephrosis as a prognostic marker in bladder cancer in a cystectomy-only series. Eur Urol. 51:690–697. 2007. View Article : Google Scholar : PubMed/NCBI

21 

Chen XP, Xiong GY, Li XS, Matin SF, Garcia M, Fang D, Wang TY, Yu W, Gong K, Song Y, et al: Predictive factors for worse pathological outcomes of upper tract urothelial carcinoma: Experience from a nationwide high-volume centre in China. BJU Int. 112:917–924. 2013.PubMed/NCBI

22 

Ito Y, Kikuchi E, Tanaka N, Miyajima A, Mikami S, Jinzaki M and Oya M: Preoperative hydronephrosis grade independently predicts worse pathological outcomes in patients undergoing nephroureterectomy for upper tract urothelial carcinoma. J Urol. 185:1621–1626. 2011. View Article : Google Scholar : PubMed/NCBI

23 

Messer JC, Terrell JD, Herman MP, Ng CK, Scherr DS, Scoll B, Boorjian SA, Uzzo RG, Wille M, Eggener SE, et al: Multi-institutional validation of the ability of preoperative hydronephrosis to predict advanced pathologic tumor stage in upper-tract urothelial carcinoma. Urol Oncol. 31:904–908. 2013. View Article : Google Scholar : PubMed/NCBI

24 

Brien JC, Shariat SF, Herman MP, Ng CK, Scherr DS, Scoll B, Uzzo RG, Wille M, Eggener SE, Terrell JD, et al: Preoperative hydronephrosis, ureteroscopic biopsy grade and urinary cytology can improve prediction of advanced upper tract urothelial carcinoma. J Urol. 184:69–73. 2010. View Article : Google Scholar : PubMed/NCBI

25 

Hwang I, Jung SI, Nam DH, Hwang EC, Kang TW, Kwon DD and Ryu SB: Preoperative hydronephrosis and diabetes mellitus predict poor prognosis in upper urinary tract urothelial carcinoma. Can Urol Assoc J. 7:E215–E220. 2013. View Article : Google Scholar : PubMed/NCBI

26 

Ma YC, Zuo L, Chen JH, Luo Q, Yu XQ, Li Y, Xu JS, Huang SM, Wang LN, Huang W, et al: Modified glomerular filtration rate estimating equation for Chinese patients with chronic kidney disease. J Am Soc Nephrol. 17:2937–2944. 2006. View Article : Google Scholar : PubMed/NCBI

27 

Bozzini G, Nison L, Colin P, Ouzzane A, Yates DR, Audenet F, Pignot G, Arvin-Berod A, Merigot O, Guy L, et al: Influence of preoperative hydronephrosis on the outcome of urothelial carcinoma of the upper urinary tract after nephroureterectomy: The results from a multi-institutional French cohort. World J Urol. 31:83–91. 2013. View Article : Google Scholar : PubMed/NCBI

28 

Akdogan B, Dogan HS, Eskicorapci SY, Sahin A, Erkan I and Ozen H: Prognostic significance of bladder tumor history and tumor location in upper tract transitional cell carcinoma. J Urol. 176:48–52. 2006. View Article : Google Scholar : PubMed/NCBI

29 

Ouzzane A, Colin P, Xylinas E, Pignot G, Ariane MM, Saint F, Hoarau N, Adam E, Azemar MD, Bensadoun H, et al: Ureteral and multifocal tumours have worse prognosis than renal pelvic tumours in urothelial carcinoma of the upper urinary tract treated by nephroureterectomy. Eur Urol. 60:1258–1265. 2011. View Article : Google Scholar : PubMed/NCBI

30 

Zhang X, Zhu Z, Zhong S, Xu T and Shen Z: Ureteral tumours showing a worse prognosis than renal pelvis tumours may be attributed to ureteral tumours more likely to have hydronephrosis and less likely to have haematuria. World J Urol. 31:155–160. 2013. View Article : Google Scholar : PubMed/NCBI

31 

Azémar MD, Comperat E, Richard F, Cussenot O and Rouprêt M: Bladder recurrence after surgery for upper urinary tract urothelial cell carcinoma: Frequency, risk factors and surveillance. Urol Oncol. 29:130–136. 2011. View Article : Google Scholar : PubMed/NCBI

32 

Silberstein JL, Power NE, Savage C, Tarin TV, Favaretto RL, Su D, Kaag MG, Herr HW and Dalbagni G: Renal function and oncologic outcomes of parenchymal sparing ureteral resection versus radical nephroureterectomy for upper tract urothelial carcinoma. J Urol. 187:429–434. 2012. View Article : Google Scholar : PubMed/NCBI

33 

Hall MC, Womack S, Sagalowsky AI, Carmody T, Erickstad MD and Roehrborn CG: Prognostic factors, recurrence and survival in transitional cell carcinoma of the upper urinary tract: A 30-year experience in 252 patients. Urology. 52:594–601. 1998. View Article : Google Scholar : PubMed/NCBI

34 

Hellenthal NJ, Shariat SF, Margulis V, Karakiewicz PI, Roscigno M, Bolenz C, Remzi M, Weizer A, Zigeuner R, Bensalah K, et al: Adjuvant chemotherapy for high risk upper tract urothelial carcinoma: Results from the upper tract urothelial carcinoma collaboration. J Urol. 182:900–906. 2009. View Article : Google Scholar : PubMed/NCBI

35 

Audenet F, Yates DR, Cussenot O and Roupret M: The role of chemotherapy in the treatment of urothelial cell carcinoma of the upper urinary tract (UUT-UCC). Urol Oncol. 31:407–413. 2013. View Article : Google Scholar : PubMed/NCBI

36 

O'Donnell PH and Stadler WM: The role of chemotherapy in upper tract urothelial carcinoma. Adv Urol. 2009:4190282009. View Article : Google Scholar

37 

Hoshino K, Kikuchi E, Tanaka N, Akita H, Ito Y, Miyajima A, Jinzaki M and Oya M: Preoperative hydronephrosis: Independent predictor for changes in renal function following nephroureterectomy. Jpn J Clin Oncol. 42:202–207. 2012. View Article : Google Scholar : PubMed/NCBI

38 

Wang SM, Lai MN, Chen PC, Pu YS, Lai MK, Hwang JS and Wang JD: Increased upper and lower tract urothelial carcinoma in patients with end-stage renal disease: A nationwide cohort study in Taiwan during 1997–2008. Biomed Res Int. 2014:1497502014.PubMed/NCBI

39 

Chen CH, Dickman KG, Moriya M, Zavadil J, Sidorenko VS, Edwards KL, Gnatenko DV, Wu L, Turesky RJ, Wu XR, et al: Aristolochic acid-associated urothelial cancer in Taiwan. Proc Natl Acad Sci USA. 109:8241–8246. 2012. View Article : Google Scholar : PubMed/NCBI

40 

Chou YH and Huang CH: Unusual clinical presentation of upper urothelial carcinoma in Taiwan. Cancer. 85:1342–1344. 1999. View Article : Google Scholar : PubMed/NCBI

41 

Yu W, Zhao YY, Shen Q, Yang XY, He Q, Song Y and Jin J: Gender-related differences in pathological characteristics of upper urinary tract urothelial carcinoma: Analysis of 597 cases. Beijing Da Xue Xue Bao. 43:522–524. 2011.(In Chinese). PubMed/NCBI

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Copy and paste a formatted citation
Spandidos Publications style
Zhang Z, Fang D, Chen X, Li X, Xiong G, Zhang L, He Q and Zhou L: Predictive role of preoperative hydronephrosis on poor pathological outcomes and prognosis in upper tract urothelial carcinoma patients: Experience from a nationwide high-volume center in China. Oncol Lett 10: 3113-3122, 2015.
APA
Zhang, Z., Fang, D., Chen, X., Li, X., Xiong, G., Zhang, L. ... Zhou, L. (2015). Predictive role of preoperative hydronephrosis on poor pathological outcomes and prognosis in upper tract urothelial carcinoma patients: Experience from a nationwide high-volume center in China. Oncology Letters, 10, 3113-3122. https://doi.org/10.3892/ol.2015.3653
MLA
Zhang, Z., Fang, D., Chen, X., Li, X., Xiong, G., Zhang, L., He, Q., Zhou, L."Predictive role of preoperative hydronephrosis on poor pathological outcomes and prognosis in upper tract urothelial carcinoma patients: Experience from a nationwide high-volume center in China". Oncology Letters 10.5 (2015): 3113-3122.
Chicago
Zhang, Z., Fang, D., Chen, X., Li, X., Xiong, G., Zhang, L., He, Q., Zhou, L."Predictive role of preoperative hydronephrosis on poor pathological outcomes and prognosis in upper tract urothelial carcinoma patients: Experience from a nationwide high-volume center in China". Oncology Letters 10, no. 5 (2015): 3113-3122. https://doi.org/10.3892/ol.2015.3653
Copy and paste a formatted citation
x
Spandidos Publications style
Zhang Z, Fang D, Chen X, Li X, Xiong G, Zhang L, He Q and Zhou L: Predictive role of preoperative hydronephrosis on poor pathological outcomes and prognosis in upper tract urothelial carcinoma patients: Experience from a nationwide high-volume center in China. Oncol Lett 10: 3113-3122, 2015.
APA
Zhang, Z., Fang, D., Chen, X., Li, X., Xiong, G., Zhang, L. ... Zhou, L. (2015). Predictive role of preoperative hydronephrosis on poor pathological outcomes and prognosis in upper tract urothelial carcinoma patients: Experience from a nationwide high-volume center in China. Oncology Letters, 10, 3113-3122. https://doi.org/10.3892/ol.2015.3653
MLA
Zhang, Z., Fang, D., Chen, X., Li, X., Xiong, G., Zhang, L., He, Q., Zhou, L."Predictive role of preoperative hydronephrosis on poor pathological outcomes and prognosis in upper tract urothelial carcinoma patients: Experience from a nationwide high-volume center in China". Oncology Letters 10.5 (2015): 3113-3122.
Chicago
Zhang, Z., Fang, D., Chen, X., Li, X., Xiong, G., Zhang, L., He, Q., Zhou, L."Predictive role of preoperative hydronephrosis on poor pathological outcomes and prognosis in upper tract urothelial carcinoma patients: Experience from a nationwide high-volume center in China". Oncology Letters 10, no. 5 (2015): 3113-3122. https://doi.org/10.3892/ol.2015.3653
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