Extra‑abdominal fibromatosis: Clinical and therapeutic considerations based on an illustrative case

Fornaro,Rosario; Caratto,Elisa; Caratto,Michela; Salerno,Alexander; Sarocchi,Francesca; Minetti,Giuseppe; Frascio,Marco; Murialdo,Roberto; Taviani,Mario

doi:10.3892/ol.2015.3684

November-2015 Volume 10 Issue 5

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November-2015 Volume 10 Issue 5

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Article

Extra‑abdominal fibromatosis: Clinical and therapeutic considerations based on an illustrative case

Authors:
- Rosario Fornaro
- Elisa Caratto
- Michela Caratto
- Alexander Salerno
- Francesca Sarocchi
- Giuseppe Minetti
- Marco Frascio
- Roberto Murialdo
- Mario Taviani
View Affiliations / Copyright

Affiliations: Department of Surgery, IRCCS San Martino Hospital, National Cancer Research Institute, University of Genoa, Genova 16132, Italy, Department of Anatomical Pathology, IRCCS San Martino Hospital, National Cancer Research Institute, University of Genoa, Genova 16132, Italy, Department of Radiology, IRCCS San Martino Hospital, National Cancer Research Institute, University of Genoa, Genova 16132, Italy, Department of Oncology, IRCCS San Martino Hospital, National Cancer Research Institute, University of Genoa, Genova 16132, Italy
Pages: 3103-3106
|
Published online on: September 8, 2015

https://doi.org/10.3892/ol.2015.3684
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Abstract

Extra‑abdominal fibromatosis is a rare, benign disease that is characterized by a local but not metastatic invasivity. In particular, desmoid tumors of the chest wall represent only 10‑20% of all deep fibromatoses. The disease occurs more often in females and has a higher incidence between puberty and the fourth decade of life. The present study reports the case of a 34‑year‑old female who came to our attention due to a voluminous mass in the right subcostal region. The magnetic resonance imaging of the upper abdomen confirmed the presence of a neoplasm localized between the anterior hepatic margin and the right costal plane. Through a right subcostal laparotomy, the voluminous 95x45x94‑mm neoplasm was excised. Histological examination showed evidence consistent with extra‑abdominal fibromatosis. The patient has not shown recurrence of the disease for 4 years since the surgery. Overall, radical surgery with disease‑free resection margins is the prime treatment option for this disease. Other therapeutic options, such as radiotherapy, hormonal therapy or treatment with imatinib mesylate, can also be considered in certain cases.

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Journals

International Journal of Molecular Medicine

International Journal of Oncology

Molecular Medicine Reports

Oncology Reports

Experimental and Therapeutic Medicine

Oncology Letters

Biomedical Reports

Molecular and Clinical Oncology

World Academy of Sciences Journal

International Journal of Functional Nutrition

International Journal of Epigenetics

Medicine International

Extra‑abdominal fibromatosis: Clinical and therapeutic considerations based on an illustrative case

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