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Oncology Letters
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Print ISSN: 1792-1074 Online ISSN: 1792-1082
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November-2015 Volume 10 Issue 5

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International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

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International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

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Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

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Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

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Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

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Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

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International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

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Case Report

Interpretation of a heterogeneous radiological response as tumor heterogeneity or a non-tumor diagnosis: A case report

  • Authors:
    • Jeong‑Seon Ryu
    • Lucia Kim
    • Woo Chul Kim
    • Jung‑Soo Kim
    • Azra Memon
    • Bo‑Rim Yi
    • Hyun‑Jung Kim
  • View Affiliations / Copyright

    Affiliations: Center for Lung Cancer, Inha University Hospital, Incheon 400‑711, Republic of Korea, Department of Pathology, Inha University Hospital, Incheon 400‑711, Republic of Korea, Department of Radiation Oncology, Inha University Hospital, Incheon 400‑711, Republic of Korea
  • Pages: 2953-2956
    |
    Published online on: September 16, 2015
       https://doi.org/10.3892/ol.2015.3709
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Abstract

Heterogeneous radiological responses (HRRs) among tumor lesions are usually observed following chemotherapy or radiation treatment in cancer patients. When HRR is observed after chemotherapy or radiation treatment, a change in anticancer treatment is recommended due to the clinically high suspicion of resistance in the majority of cases. The present study reports the case report of a patient with limited‑stage small cell lung cancer, diagnosed by bronchoscopy, who received concurrent chemoradiation therapy. Upon response evaluation, the majority of lesions irradiated had nearly completely disappeared following treatment, but one lesion had apparently increased in size. For histological confirmation, a percutaneous needle biopsy for the lesion was performed, however, non‑specific necrosis was found and the results were inconclusive for the differentiation of other causes from tumor necrosis. Several acid‑fast bacilli were identified on Ziehl‑Neelsen staining for the differential diagnosis. This case suggests that a non‑tumor diagnosis should be considered when HRR presents after treatment that is expected to result in a higher response rate, particularly in tuberculosis endemic areas.
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Copy and paste a formatted citation
Spandidos Publications style
Ryu JS, Kim L, Kim WC, Kim JS, Memon A, Yi BR and Kim HJ: Interpretation of a heterogeneous radiological response as tumor heterogeneity or a non-tumor diagnosis: A case report. Oncol Lett 10: 2953-2956, 2015.
APA
Ryu, J., Kim, L., Kim, W.C., Kim, J., Memon, A., Yi, B., & Kim, H. (2015). Interpretation of a heterogeneous radiological response as tumor heterogeneity or a non-tumor diagnosis: A case report. Oncology Letters, 10, 2953-2956. https://doi.org/10.3892/ol.2015.3709
MLA
Ryu, J., Kim, L., Kim, W. C., Kim, J., Memon, A., Yi, B., Kim, H."Interpretation of a heterogeneous radiological response as tumor heterogeneity or a non-tumor diagnosis: A case report". Oncology Letters 10.5 (2015): 2953-2956.
Chicago
Ryu, J., Kim, L., Kim, W. C., Kim, J., Memon, A., Yi, B., Kim, H."Interpretation of a heterogeneous radiological response as tumor heterogeneity or a non-tumor diagnosis: A case report". Oncology Letters 10, no. 5 (2015): 2953-2956. https://doi.org/10.3892/ol.2015.3709
Copy and paste a formatted citation
x
Spandidos Publications style
Ryu JS, Kim L, Kim WC, Kim JS, Memon A, Yi BR and Kim HJ: Interpretation of a heterogeneous radiological response as tumor heterogeneity or a non-tumor diagnosis: A case report. Oncol Lett 10: 2953-2956, 2015.
APA
Ryu, J., Kim, L., Kim, W.C., Kim, J., Memon, A., Yi, B., & Kim, H. (2015). Interpretation of a heterogeneous radiological response as tumor heterogeneity or a non-tumor diagnosis: A case report. Oncology Letters, 10, 2953-2956. https://doi.org/10.3892/ol.2015.3709
MLA
Ryu, J., Kim, L., Kim, W. C., Kim, J., Memon, A., Yi, B., Kim, H."Interpretation of a heterogeneous radiological response as tumor heterogeneity or a non-tumor diagnosis: A case report". Oncology Letters 10.5 (2015): 2953-2956.
Chicago
Ryu, J., Kim, L., Kim, W. C., Kim, J., Memon, A., Yi, B., Kim, H."Interpretation of a heterogeneous radiological response as tumor heterogeneity or a non-tumor diagnosis: A case report". Oncology Letters 10, no. 5 (2015): 2953-2956. https://doi.org/10.3892/ol.2015.3709
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