Primary synovial sarcoma of the kidney: A case report

  • Authors:
    • Zijian Wang
    • Zhaohui Zhong
    • Liang Zhu
    • Wei Xiong
    • Cizhong Pan
    • Xinjun Wang
    • Zhichao Huang
    • Xiaokun Zhao
  • View Affiliations

  • Published online on: September 25, 2015     https://doi.org/10.3892/ol.2015.3744
  • Pages: 3542-3544
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Abstract

Synovial sarcoma (SS) is a soft‑tissue tumor with a unique t(X;18)(p11.2;q11.2) chromosomal translocation that can be identified by polymerase chain reaction in tissue homogenates. Generally, the tumor occurs in the proximity of the joints. The current study presents the case of a 54‑year‑old female with primary SS (PSS) of the right kidney; this is an extremely rare tumor accounting for <2% of malignant renal carcinomas. The patient presented with an interrupted right flank pain of 20 years duration, with a precipitating factor of a hematuria of 8 days. Abdominal computerized tomography (CT) scan revealed a heterogeneous, unclear-marginated soft tissue arising in the upper pole of the right kidney with solid, necrotic components and heterogeneous enhancement. Renal cell carcinoma was diagnosed pre-operatively. A right nephrectomy was performed, and the patient is currently free of metastasis 12 months after the surgery. The current treatment for renal SS includes surgical resection and ifosfamide‑based chemotherapy. To the best of our knowledge, <50 cases have been reported in the English literature. Urologists should be aware of the possibility of malignancy in cystic renal masses and consider a diagnosis of SS. Along with the case report, the current study presents a literature review on the diagnosis and treatment of PSS.
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December-2015
Volume 10 Issue 6

Print ISSN: 1792-1074
Online ISSN:1792-1082

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Copy and paste a formatted citation
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Spandidos Publications style
Wang Z, Zhong Z, Zhu L, Xiong W, Pan C, Wang X, Huang Z and Zhao X: Primary synovial sarcoma of the kidney: A case report. Oncol Lett 10: 3542-3544, 2015
APA
Wang, Z., Zhong, Z., Zhu, L., Xiong, W., Pan, C., Wang, X. ... Zhao, X. (2015). Primary synovial sarcoma of the kidney: A case report. Oncology Letters, 10, 3542-3544. https://doi.org/10.3892/ol.2015.3744
MLA
Wang, Z., Zhong, Z., Zhu, L., Xiong, W., Pan, C., Wang, X., Huang, Z., Zhao, X."Primary synovial sarcoma of the kidney: A case report". Oncology Letters 10.6 (2015): 3542-3544.
Chicago
Wang, Z., Zhong, Z., Zhu, L., Xiong, W., Pan, C., Wang, X., Huang, Z., Zhao, X."Primary synovial sarcoma of the kidney: A case report". Oncology Letters 10, no. 6 (2015): 3542-3544. https://doi.org/10.3892/ol.2015.3744