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December-2015 Volume 10 Issue 6

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Review

Function and clinical potential of microRNAs in hepatocellular carcinoma (Review)

  • Authors:
    • Lijuan Wang
    • Yongfang Yue
    • Xian Wang
    • Hongchuan Jin
  • View Affiliations / Copyright

    Affiliations: Department of Hematology, Hematology Laboratory, Linyi People's Hospital, Shandong University, Linyi, Shandong 276003, P.R. China, Department of Medical Oncology, Institute of Clinical Science, Sir Run Run Shaw Hospital, Medical School of Zhejiang University, Hangzhou, Zhejiang 310000, P.R. China
  • Pages: 3345-3353
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    Published online on: September 29, 2015
       https://doi.org/10.3892/ol.2015.3759
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Abstract

MicroRNAs (miRNAs) are small non‑coding RNAs involved in the initiation and progression of several types of human cancer, including hepatocellular carcinoma (HCC), which is one of the most common types of cancer and the third leading cause of cancer‑related mortality worldwide. Mounting evidence has demonstrated that miRNAs play a vital role in HCC, hepatitis, alcoholic liver disease, liver cell development and the metabolic functions of the liver. The aim of the present review was to summarize the most recent findings on the functions of miRNAs in the liver and discuss their potential roles in the diagnosis, prognosis and treatment of HCC.
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Copy and paste a formatted citation
Spandidos Publications style
Wang L, Yue Y, Wang X and Jin H: Function and clinical potential of microRNAs in hepatocellular carcinoma (Review). Oncol Lett 10: 3345-3353, 2015.
APA
Wang, L., Yue, Y., Wang, X., & Jin, H. (2015). Function and clinical potential of microRNAs in hepatocellular carcinoma (Review). Oncology Letters, 10, 3345-3353. https://doi.org/10.3892/ol.2015.3759
MLA
Wang, L., Yue, Y., Wang, X., Jin, H."Function and clinical potential of microRNAs in hepatocellular carcinoma (Review)". Oncology Letters 10.6 (2015): 3345-3353.
Chicago
Wang, L., Yue, Y., Wang, X., Jin, H."Function and clinical potential of microRNAs in hepatocellular carcinoma (Review)". Oncology Letters 10, no. 6 (2015): 3345-3353. https://doi.org/10.3892/ol.2015.3759
Copy and paste a formatted citation
x
Spandidos Publications style
Wang L, Yue Y, Wang X and Jin H: Function and clinical potential of microRNAs in hepatocellular carcinoma (Review). Oncol Lett 10: 3345-3353, 2015.
APA
Wang, L., Yue, Y., Wang, X., & Jin, H. (2015). Function and clinical potential of microRNAs in hepatocellular carcinoma (Review). Oncology Letters, 10, 3345-3353. https://doi.org/10.3892/ol.2015.3759
MLA
Wang, L., Yue, Y., Wang, X., Jin, H."Function and clinical potential of microRNAs in hepatocellular carcinoma (Review)". Oncology Letters 10.6 (2015): 3345-3353.
Chicago
Wang, L., Yue, Y., Wang, X., Jin, H."Function and clinical potential of microRNAs in hepatocellular carcinoma (Review)". Oncology Letters 10, no. 6 (2015): 3345-3353. https://doi.org/10.3892/ol.2015.3759
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