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Article

Analysis of clinical features and prognosis of malignant triton tumor: A report of two cases and literature review

  • Authors:
    • Guo Li
    • Chao Liu
    • Yong Liu
    • Fang Xu
    • Zhongwu Su
    • Yunyun Wang
    • Shuling Ren
    • Tengbo Deng
    • Donghai Huang
    • Yongquan Tian
    • Yuanzheng Qiu
  • View Affiliations / Copyright

    Affiliations: Department of Otolaryngology and Head‑Neck Surgery, Xiangya Hospital, Central South University, Changsha, Hunan 410008, P.R. China
  • Pages: 3551-3556
    |
    Published online on: September 29, 2015
       https://doi.org/10.3892/ol.2015.3762
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Abstract

Malignant triton tumor (MTT) is a malignant peripheral nerve sheath tumor with rhabdomyoblastic differentiation. The prognosis of patients is poor, and due to its rarity, large case studies are lacking. The aim of this study is to describe the clinical features and identify potential prognostic factors. Two patients with MTT in the head and neck treated at our department are reported. A literature search revealed another 198 published cases. All of these cases then went through a retrospective analysis. The ratio of male‑to‑female incidence was 1.5:1, and the median age at diagnosis was 29 years. In 41.7% of cases it occurred in patients with neurofibromatosis type 1. The five‑year survival of MTT was found to be just 35%. Cox proportional hazards analysis revealed that complete resection (hazard ratio, 0.396; P=0.032) and metastases (hazard ratio, 3.188; P=0.004) were associated with mortality, indicating that complete resection may lead to a longer life span, and that the existence of metastasis suggested a worse prognosis for patients with MTT.
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Copy and paste a formatted citation
Spandidos Publications style
Li G, Liu C, Liu Y, Xu F, Su Z, Wang Y, Ren S, Deng T, Huang D, Tian Y, Tian Y, et al: Analysis of clinical features and prognosis of malignant triton tumor: A report of two cases and literature review. Oncol Lett 10: 3551-3556, 2015.
APA
Li, G., Liu, C., Liu, Y., Xu, F., Su, Z., Wang, Y. ... Qiu, Y. (2015). Analysis of clinical features and prognosis of malignant triton tumor: A report of two cases and literature review. Oncology Letters, 10, 3551-3556. https://doi.org/10.3892/ol.2015.3762
MLA
Li, G., Liu, C., Liu, Y., Xu, F., Su, Z., Wang, Y., Ren, S., Deng, T., Huang, D., Tian, Y., Qiu, Y."Analysis of clinical features and prognosis of malignant triton tumor: A report of two cases and literature review". Oncology Letters 10.6 (2015): 3551-3556.
Chicago
Li, G., Liu, C., Liu, Y., Xu, F., Su, Z., Wang, Y., Ren, S., Deng, T., Huang, D., Tian, Y., Qiu, Y."Analysis of clinical features and prognosis of malignant triton tumor: A report of two cases and literature review". Oncology Letters 10, no. 6 (2015): 3551-3556. https://doi.org/10.3892/ol.2015.3762
Copy and paste a formatted citation
x
Spandidos Publications style
Li G, Liu C, Liu Y, Xu F, Su Z, Wang Y, Ren S, Deng T, Huang D, Tian Y, Tian Y, et al: Analysis of clinical features and prognosis of malignant triton tumor: A report of two cases and literature review. Oncol Lett 10: 3551-3556, 2015.
APA
Li, G., Liu, C., Liu, Y., Xu, F., Su, Z., Wang, Y. ... Qiu, Y. (2015). Analysis of clinical features and prognosis of malignant triton tumor: A report of two cases and literature review. Oncology Letters, 10, 3551-3556. https://doi.org/10.3892/ol.2015.3762
MLA
Li, G., Liu, C., Liu, Y., Xu, F., Su, Z., Wang, Y., Ren, S., Deng, T., Huang, D., Tian, Y., Qiu, Y."Analysis of clinical features and prognosis of malignant triton tumor: A report of two cases and literature review". Oncology Letters 10.6 (2015): 3551-3556.
Chicago
Li, G., Liu, C., Liu, Y., Xu, F., Su, Z., Wang, Y., Ren, S., Deng, T., Huang, D., Tian, Y., Qiu, Y."Analysis of clinical features and prognosis of malignant triton tumor: A report of two cases and literature review". Oncology Letters 10, no. 6 (2015): 3551-3556. https://doi.org/10.3892/ol.2015.3762
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