Paraganglioma of the urinary bladder with chromosome duplications detected by fluorescence in situ hybridization in urine exfoliated cells: A case report

  • Authors:
    • Chunguang Yang
    • Zheng Liu
    • Ruzhu Lan
    • Zhihua Wang
    • Zhiquan Hu
    • Zhiqiang Chen
    • Zhangqun Ye
  • View Affiliations

  • Published online on: November 18, 2015     https://doi.org/10.3892/ol.2015.3941
  • Pages: 795-797
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Abstract

Paragangliomas of the urinary bladder are rare neoplasms derived from chromaffin tissue with a chromosomal imbalance. Their preoperative diagnosis and assessment of malignant potential remain significant challenges for urologists. The current report presents the case of a 34‑year‑old male who presented with a history of paroxysmal gross hematuria lasting for 7 months. Chromosome duplications were detected by fluorescence in situ hybridization (FISH) in urine exfoliated cells, and the diagnosis was confirmed by histopathology following a transurethral resection. To the best of our knowledge, this is the first reported case of urinary bladder paraganglioma in which chromosomal duplications were detected by FISH in urine exfoliated cells. This may be helpful to its differential diagnosis and malignant potential determination.
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January-2016
Volume 11 Issue 1

Print ISSN: 1792-1074
Online ISSN:1792-1082

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Spandidos Publications style
Yang C, Liu Z, Lan R, Wang Z, Hu Z, Chen Z and Ye Z: Paraganglioma of the urinary bladder with chromosome duplications detected by fluorescence in situ hybridization in urine exfoliated cells: A case report. Oncol Lett 11: 795-797, 2016
APA
Yang, C., Liu, Z., Lan, R., Wang, Z., Hu, Z., Chen, Z., & Ye, Z. (2016). Paraganglioma of the urinary bladder with chromosome duplications detected by fluorescence in situ hybridization in urine exfoliated cells: A case report. Oncology Letters, 11, 795-797. https://doi.org/10.3892/ol.2015.3941
MLA
Yang, C., Liu, Z., Lan, R., Wang, Z., Hu, Z., Chen, Z., Ye, Z."Paraganglioma of the urinary bladder with chromosome duplications detected by fluorescence in situ hybridization in urine exfoliated cells: A case report". Oncology Letters 11.1 (2016): 795-797.
Chicago
Yang, C., Liu, Z., Lan, R., Wang, Z., Hu, Z., Chen, Z., Ye, Z."Paraganglioma of the urinary bladder with chromosome duplications detected by fluorescence in situ hybridization in urine exfoliated cells: A case report". Oncology Letters 11, no. 1 (2016): 795-797. https://doi.org/10.3892/ol.2015.3941