Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Oncology Letters
      • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Biomedical Reports
      • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • Information for Authors
    • Information for Reviewers
    • Information for Librarians
    • Information for Advertisers
    • Conferences
  • Language Editing
Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • For Authors
    • For Reviewers
    • For Librarians
    • For Advertisers
    • Conferences
  • Language Editing
Login Register Submit
  • This site uses cookies
  • You can change your cookie settings at any time by following the instructions in our Cookie Policy. To find out more, you may read our Privacy Policy.

    I agree
Search articles by DOI, keyword, author or affiliation
Search
Advanced Search
presentation
Oncology Letters
Join Editorial Board Propose a Special Issue
Print ISSN: 1792-1074 Online ISSN: 1792-1082
Journal Cover
January-2016 Volume 11 Issue 1

Full Size Image

Sign up for eToc alerts
Recommend to Library

Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

Journal Cover
January-2016 Volume 11 Issue 1

Full Size Image

Sign up for eToc alerts
Recommend to Library

  • Article
  • Citations
    • Cite This Article
    • Download Citation
    • Create Citation Alert
    • Remove Citation Alert
    • Cited By
  • Similar Articles
    • Related Articles (in Spandidos Publications)
    • Similar Articles (Google Scholar)
    • Similar Articles (PubMed)
  • Download PDF
  • Download XML
  • View XML
Article

Expression and clinical significance of cyclooxygenase‑2 and interleukin‑32 in primary gastric B‑cell lymphoma

  • Authors:
    • Yingying Cui
    • Zhenchang Sun
    • Xin Li
    • Changsen Leng
    • Lei Zhang
    • Xiaorui Fu
    • Ling Li
    • Xudong Zhang
    • Yu Chang
    • Feifei Nan
    • Zhaoming Li
    • Jiaqin Yan
    • Mingzhi Zhang
    • Wencai Li
    • Guannan Wang
    • Dandan Zhang
    • Yaozhen Ma
  • View Affiliations / Copyright

    Affiliations: Department of Oncology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan 450052, P.R. China, Department of Thoracic Surgery, The Affiliated Cancer Hospital of Zhengzhou University, Zhengzhou, Henan 450008, P.R. China, Department of Pathology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan 450052, P.R. China
  • Pages: 693-698
    |
    Published online on: November 20, 2015
       https://doi.org/10.3892/ol.2015.3950
  • Expand metrics +
Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )
Metrics: Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )
Cited By (CrossRef): 0 citations Loading Articles...

This article is mentioned in:



Abstract

Cyclooxygenase‑2 (COX‑2) and interleukin‑32 (IL‑32) expression has been examined in various carcinomas and inflammations, and has been suggested to be significant in tumor progression and prognosis. The present study was conducted to investigate the expression of COX‑2 and IL‑32 in primary gastric B‑cell lymphoma in order to define their clinical significance and their association with Helicobacter pylori (Hp) infection. COX‑2 and IL‑32 protein expression was detected in 31 primary gastric B‑cell lymphoma patients and 19 chronic gastritis patients with immunohistochemistry. COX‑2 and IL‑32 expression was significantly higher in primary gastric lymphoma (PGL) tissues compared with gastritis tissues (51.6 vs. 21.1% for COX‑2, P=0.032; and 58.1 vs. 26.3% for IL‑32, P=0.029) and was significantly higher in Hp+ lymphoma tissues compared with Hp‑ lymphoma tissues (66.7 vs. 20% for COX‑2, P=0.015; and 71.4 vs. 30% for IL‑32, P=0.029). In the PGL tissues, the expression level of COX‑2 was positively correlated with the expression level of IL‑32, and the two were each positively correlated with Hp infection (P=0.004 for COX‑2 and IL‑32; P=0.01 for COX‑2 and Hp infection; and P=0.003 for IL‑32 and Hp infection). COX‑2 expression was found to be significantly associated (P<0.05) with an aggressive tumor type, higher expression of Ki‑67, frequent lymph node metastasis and advanced stage. IL‑32 expression was found to be significantly correlated (P<0.05) with frequent lymph node metastasis and an advanced stage. The survival time was longer in the COX‑2‑ and IL‑32‑ lymphoma patients compared with the COX‑2+ and IL‑32+ lymphoma patients, but these differences were not statistically significant. These results suggested that Hp infection and the expression of COX‑2 and IL‑32 were closely linked with each other, and that the overexpression of COX‑2 and IL‑32 was correlated with tumor progression in primary gastric B‑cell lymphoma, thus indicating potential novel therapeutic target.
View Figures

Figure 1

Figure 2

Figure 3

View References

1 

Huang J, Jiang W, Xu R, Huang H, Lv Y, Xia Z, Sun X, Guan Z, Lin T and Li Z: Primary gastric non-Hodgkin's lymphoma in Chinese patients: Clinical characteristics and prognostic factors. BMC Cancer. 10:3582010. View Article : Google Scholar : PubMed/NCBI

2 

Psyrri A, Papageorgiou S and Economopoulos T: Primary extranodal lymphomas of stomach: Clinical presentation, diagnostic pitfalls and management. Ann Oncol. 19:1992–1999. 2008. View Article : Google Scholar : PubMed/NCBI

3 

Nakamura S, Matsumoto T, Iida M, Yao T and Tsuneyoshi M: Primary gastrointestinal lymphoma in Japan: A clinicopathologic analysis of 455 patients with special reference to its time trends. Cancer. 97:2462–2473. 2003. View Article : Google Scholar : PubMed/NCBI

4 

D'Amore F, Christensen BE, Thorling K, Pedersen M, Jensen MK, Boesen AM, Andersen E, Johansen P and Mortensen LS: Incidence, presenting features and prognosis of low-grade B-cell non-Hodgkin's lymphomas. Population-based data from a Danish lymphoma registry. Leuk Lymphoma. 12:69–77. 1993. View Article : Google Scholar : PubMed/NCBI

5 

Koch P, Probst A, Berdel WE, Willich NA, Reinartz G, Brockmann J, Liersch R, del Valle F, Clasen H, Hirt C, et al: Treatment results in localized primary gastric lymphoma: Data of patients registered within the German multicenter study (GIT NHL 02/96). J Clin Oncol. 23:7050–7059. 2005. View Article : Google Scholar : PubMed/NCBI

6 

Wang F, Meng W, Wang B and Qiao L: Helicobacter pylori-induced gastric inflammation and gastric cancer. Cancer Lett. 345:196–202. 2014. View Article : Google Scholar : PubMed/NCBI

7 

Campuzano-Maya G: Hematologic manifestations of Helicobacter pylori infection. World J Gastroenterol. 20:12818–12838. 2014. View Article : Google Scholar : PubMed/NCBI

8 

Konturek PC, Hartwich A, Zuchowicz M, Labza H, Pierzchalski P, Karczewska E, Bielanski W, Hahn EG and Konturek SJ: Helicobacter pylori, gastrin and cyclooxygenases in gastric cancer. J Physiol Pharmacol. 51:737–749. 2000.PubMed/NCBI

9 

Yamac D, Ayyildiz T, Coşkun U, Akyürek N, Dursun A, Seckin S and Koybasioglu F: Cyclooxygenase-2 expression and its association with angiogenesis, Helicobacter pylori, and clinicopathologic characteristics of gastric carcinoma. Pathol Res Pract. 204:527–536. 2008. View Article : Google Scholar : PubMed/NCBI

10 

Akdis M, Burgler S, Crameri R, Eiwegger T, Fujita H, Gomez E, Klunker S, Meyer N, O'Mahony L, Palomares O, et al: Interleukins, from 1 to 37, and interferon-γ: receptors, functions, and roles in diseases. J Allergy Clin Immunol. 127:701–721–e701–770. 2011. View Article : Google Scholar

11 

Zeng Q, Li S, Zhou Y, Ou W, Cai X, Zhang L, Huang W, Huang L and Wang Q: Interleukin-32 contributes to invasion and metastasis of primary lung adenocarcinoma via NF-κB induced matrix metalloproteinases 2 and 9 expression. Cytokine. 65:24–32. 2014. View Article : Google Scholar : PubMed/NCBI

12 

Peng LS, Zhuang Y, Li WH, Zhou YY, Wang TT, Chen N, Cheng P, Li BS, Guo H, Yang SM, et al: Elevated interleukin-32 expression is associated with Helicobacter pylori-related gastritis. PLoS One. 9:e882702014. View Article : Google Scholar : PubMed/NCBI

13 

Gui M, Zhang H, Zhong K, Li Y, Sun J and Wang L: Clinical significance of interleukin-32 expression in patients with rheumatoid arthritis. Asian Pac J Allergy Immunol. 31:73–78. 2013.PubMed/NCBI

14 

Lee S, Kim JH, Kim H, Kang JW, Kim SH, Yang Y, Kim J, Park J, Park S, Hong J, et al: Activation of the interleukin-32 pro-inflammatory pathway in response to human papillomavirus infection and over-expression of interleukin-32 controls the expression of the human papillomavirus oncogene. Immunology. 132:410–420. 2011. View Article : Google Scholar : PubMed/NCBI

15 

Li W, Liu Y, Mukhtar MM, Gong R, Pan Y, Rasool ST, Gao Y, Kang L, Hao Q, Peng G, et al: Activation of interleukin-32 pro-inflammatory pathway in response to influenza A virus infection. PLoS One. 3:e19852008. View Article : Google Scholar : PubMed/NCBI

16 

Lewin KJ, Ranchod M and Dorfman RF: Lymphomas of the gastrointestinal tract: A study of 117 cases presenting with gastrointestinal disease. Cancer. 42:693–707. 1978. View Article : Google Scholar : PubMed/NCBI

17 

Tomonaga M: Outline and direction of revised WHO classification of Tumors of Haematopoietic and Lymphoid Tissues. Rinsho Ketsueki. 50:1401–1406. 2009.(In Japanese). PubMed/NCBI

18 

Rohatiner A, d'Amore F, Coiffier B, Crowther D, Gospodarowicz M, Isaacson P, Lister TA, Norton A, Salem P, Shipp M, et al: Report on a workshop convened to discuss the pathological and staging classifications of gastrointestinal tract lymphoma. Ann Oncol. 5:397–400. 1994.PubMed/NCBI

19 

Li Y, Li S, Sun D, Song L and Liu X: Expression of 15-hydroxyprostaglandin dehydrogenase and cyclooxygenase-2 in non-small cell lung cancer: Correlations with angiogenesis and prognosis. Oncol Lett. 8:1589–1594. 2014.PubMed/NCBI

20 

Bayerdörffer E, Neubauer A, Rudolph B, Thiede C, Lehn N, Eidt S and Stolte M: MALT Lymphoma Study Group: Regression of primary gastric lymphoma of mucosa-associated lymphoid tissue type after cure of Helicobacter pylori infection. Lancet. 345:1591–1594. 1995. View Article : Google Scholar : PubMed/NCBI

21 

Wündisch T, Thiede C, Morgner A, Dempfle A, Günther A, Liu H, Ye H, Du MQ, Kim TD, Bayerdörffer E, et al: Long-term follow-up of gastric MALT lymphoma after Helicobacter pylori eradication. J Clin Oncol. 23:8018–8024. 2005. View Article : Google Scholar : PubMed/NCBI

22 

Kuo SH, Yeh KH, Wu MS, Lin CW, Hsu PN, Wang HP, Chen LT and Cheng AL: Helicobacter pylori eradication therapy is effective in the treatment of early-stage H pylori-positive gastric diffuse large B-cell lymphomas. Blood. 119:4838–4844; quiz 5057. 2012. View Article : Google Scholar : PubMed/NCBI

23 

Hazar B, Ergin M, Seyrek E, Erdoğan S, Tuncer I and Hakverdi S: Cyclooxygenase-2 (Cox-2) expression in lymphomas. Leuk Lymphoma. 45:1395–1399. 2004. View Article : Google Scholar : PubMed/NCBI

24 

Paydas S, Ergin M, Seydaoglu G, Erdogan S and Yavuz S: Prognostic (corrected) significance of angiogenic/lymphangiogenic, anti-apoptotic, inflammatory and viral factors in 88 cases with diffuse large B cell lymphoma and review of the literature. Leuk Res. 33:1627–1635. 2009. View Article : Google Scholar : PubMed/NCBI

25 

Wun T, McKnight H and Tuscano JM: Increased cyclooxygenase-2 (COX-2): A potential role in the pathogenesis of lymphoma. Leuk Res. 28:179–190. 2004. View Article : Google Scholar : PubMed/NCBI

26 

Suga H, Sugaya M, Miyagaki T, Kawaguchi M, Fujita H, Asano Y, Tada Y, Kadono T and Sato S: The role of IL-32 in cutaneous T-cell lymphoma. J Invest Dermatol. 134:1428–1435. 2014. View Article : Google Scholar : PubMed/NCBI

27 

Miettinen A, Karttunen TJ and Alavaikko M: Lymphocytic gastritis and Helicobacter pylori infection in gastric lymphoma. Gut. 37:471–476. 1995. View Article : Google Scholar : PubMed/NCBI

28 

Bartchewsky W Jr, Martini MR, Masiero M, Squassoni AC, Alvarez MC, Ladeira MS, Salvatore D, Trevisan M, Pedrazzoli J Jr and Ribeiro ML: Effect of Helicobacter pylori infection on IL-8, IL-1β and COX-2 expression in patients with chronic gastritis and gastric cancer. Scand J Gastroenterol. 44:153–161. 2009. View Article : Google Scholar : PubMed/NCBI

29 

Denkert C, Winzer KJ, Müller BM, Weichert W, Pest S, Köbel M, Kristiansen G, Reles A, Siegert A, Guski H, et al: Elevated expression of cyclooxygenase-2 is a negative prognostic factor for disease free survival and overall survival in patients with breast carcinoma. Cancer. 97:2978–2987. 2003. View Article : Google Scholar : PubMed/NCBI

30 

Li HL, Sun BZ and Ma FC: Expression of COX-2, iNOS, p53 and Ki-67 in gastric mucosa-associated lymphoid tissue lymphoma. World J Gastroenterol. 10:1862–1866. 2004. View Article : Google Scholar : PubMed/NCBI

31 

Kato Y, Nishihara H, Mohri H, Kanno H, Kobayashi H, Kimura T, Tanino M, Terasaka S and Tanaka S: Clinicopathological evaluation of cyclooxygenase-2 expression in meningioma: Immunohistochemical analysis of 76 cases of low and high-grade meningioma. Brain Tumor Pathol. 31:23–30. 2014. View Article : Google Scholar : PubMed/NCBI

32 

Al-Moundhri MS, Al-Hadabi I, Al-Mawaly K, Kumar S, Al-Lawati FA, Bhatnager G, Kuruvila S, Al-Hamdani A, El-Sayed SM and Al-Bahrani B: Prognostic significance of cyclooxygenase-2, epidermal growth factor receptor 1, and microvascular density in gastric cancer. Med Oncol. 29:1739–1747. 2012. View Article : Google Scholar : PubMed/NCBI

33 

Ishigami S, Arigami T, Uchikado Y, Setoyama T, Kita Y, Sasaki K, Okumura H, Kurahara H, Kijima Y, Harada A, et al: IL-32 expression is an independent prognostic marker for gastric cancer. Med Oncol. 30:4722013. View Article : Google Scholar : PubMed/NCBI

34 

Koh YW, Park C, Yoon DH, Suh C and Huh J: Prognostic significance of COX-2 expression and correlation with Bcl-2 and VEGF expression, microvessel density, and clinical variables in classical Hodgkin lymphoma. Am J Surg Pathol. 37:1242–1251. 2013. View Article : Google Scholar : PubMed/NCBI

Related Articles

  • Abstract
  • View
  • Download
  • Twitter
Copy and paste a formatted citation
Spandidos Publications style
Cui Y, Sun Z, Li X, Leng C, Zhang L, Fu X, Li L, Zhang X, Chang Y, Nan F, Nan F, et al: Expression and clinical significance of cyclooxygenase‑2 and interleukin‑32 in primary gastric B‑cell lymphoma. Oncol Lett 11: 693-698, 2016.
APA
Cui, Y., Sun, Z., Li, X., Leng, C., Zhang, L., Fu, X. ... Ma, Y. (2016). Expression and clinical significance of cyclooxygenase‑2 and interleukin‑32 in primary gastric B‑cell lymphoma. Oncology Letters, 11, 693-698. https://doi.org/10.3892/ol.2015.3950
MLA
Cui, Y., Sun, Z., Li, X., Leng, C., Zhang, L., Fu, X., Li, L., Zhang, X., Chang, Y., Nan, F., Li, Z., Yan, J., Zhang, M., Li, W., Wang, G., Zhang, D., Ma, Y."Expression and clinical significance of cyclooxygenase‑2 and interleukin‑32 in primary gastric B‑cell lymphoma". Oncology Letters 11.1 (2016): 693-698.
Chicago
Cui, Y., Sun, Z., Li, X., Leng, C., Zhang, L., Fu, X., Li, L., Zhang, X., Chang, Y., Nan, F., Li, Z., Yan, J., Zhang, M., Li, W., Wang, G., Zhang, D., Ma, Y."Expression and clinical significance of cyclooxygenase‑2 and interleukin‑32 in primary gastric B‑cell lymphoma". Oncology Letters 11, no. 1 (2016): 693-698. https://doi.org/10.3892/ol.2015.3950
Copy and paste a formatted citation
x
Spandidos Publications style
Cui Y, Sun Z, Li X, Leng C, Zhang L, Fu X, Li L, Zhang X, Chang Y, Nan F, Nan F, et al: Expression and clinical significance of cyclooxygenase‑2 and interleukin‑32 in primary gastric B‑cell lymphoma. Oncol Lett 11: 693-698, 2016.
APA
Cui, Y., Sun, Z., Li, X., Leng, C., Zhang, L., Fu, X. ... Ma, Y. (2016). Expression and clinical significance of cyclooxygenase‑2 and interleukin‑32 in primary gastric B‑cell lymphoma. Oncology Letters, 11, 693-698. https://doi.org/10.3892/ol.2015.3950
MLA
Cui, Y., Sun, Z., Li, X., Leng, C., Zhang, L., Fu, X., Li, L., Zhang, X., Chang, Y., Nan, F., Li, Z., Yan, J., Zhang, M., Li, W., Wang, G., Zhang, D., Ma, Y."Expression and clinical significance of cyclooxygenase‑2 and interleukin‑32 in primary gastric B‑cell lymphoma". Oncology Letters 11.1 (2016): 693-698.
Chicago
Cui, Y., Sun, Z., Li, X., Leng, C., Zhang, L., Fu, X., Li, L., Zhang, X., Chang, Y., Nan, F., Li, Z., Yan, J., Zhang, M., Li, W., Wang, G., Zhang, D., Ma, Y."Expression and clinical significance of cyclooxygenase‑2 and interleukin‑32 in primary gastric B‑cell lymphoma". Oncology Letters 11, no. 1 (2016): 693-698. https://doi.org/10.3892/ol.2015.3950
Follow us
  • Twitter
  • LinkedIn
  • Facebook
About
  • Spandidos Publications
  • Careers
  • Cookie Policy
  • Privacy Policy
How can we help?
  • Help
  • Live Chat
  • Contact
  • Email to our Support Team