Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Oncology Letters
      • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Biomedical Reports
      • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • Information for Authors
    • Information for Reviewers
    • Information for Librarians
    • Information for Advertisers
    • Conferences
  • Language Editing
Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • For Authors
    • For Reviewers
    • For Librarians
    • For Advertisers
    • Conferences
  • Language Editing
Login Register Submit
  • This site uses cookies
  • You can change your cookie settings at any time by following the instructions in our Cookie Policy. To find out more, you may read our Privacy Policy.

    I agree
Search articles by DOI, keyword, author or affiliation
Search
Advanced Search
presentation
Oncology Letters
Join Editorial Board Propose a Special Issue
Print ISSN: 1792-1074 Online ISSN: 1792-1082
Journal Cover
February-2016 Volume 11 Issue 2

Full Size Image

Sign up for eToc alerts
Recommend to Library

Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

Journal Cover
February-2016 Volume 11 Issue 2

Full Size Image

Sign up for eToc alerts
Recommend to Library

  • Article
  • Citations
    • Cite This Article
    • Download Citation
    • Create Citation Alert
    • Remove Citation Alert
    • Cited By
  • Similar Articles
    • Related Articles (in Spandidos Publications)
    • Similar Articles (Google Scholar)
    • Similar Articles (PubMed)
  • Download PDF
  • Download XML
  • View XML
Case Report

Primary intratesticular rhabdomyosarcoma: A case report and literature review

  • Authors:
    • Jun Yi
    • Dong‑Ai Zhou
    • Ji‑Rong Huo
    • Yun‑Hua Wang
    • Jin‑An Ma
  • View Affiliations / Copyright

    Affiliations: Department of Gastroenterology, The Second Xiangya Hospital of Central South University, Changsha, Hunan 410011, P.R. China, Department of Oncology, The Second Xiangya Hospital of Central South University, Changsha, Hunan 410011, P.R. China, Positron Emission Tomography‑Computed Tomography Center, The Second Xiangya Hospital of Central South University, Changsha, Hunan 410011, P.R. China
  • Pages: 1016-1020
    |
    Published online on: December 2, 2015
       https://doi.org/10.3892/ol.2015.3987
  • Expand metrics +
Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )
Metrics: Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )
Cited By (CrossRef): 0 citations Loading Articles...

This article is mentioned in:



Abstract

Rhabdomyosarcoma (RMS) that primarily occurs in the testes is particularly rare, with only retrospective studies and sporadic cases reported in the literature. The present study describes the case of a large, primary intratesticular RMS (ITRMS) that was treated with a radical inguinal orchiectomy (RIO) and a regimen of chemotherapy. The study also presents a review of the literature regarding primary ITRMSs, aiming to elucidate the clinical characteristics and optimal treatment of the disease. A 14‑year‑old male presented with a 1‑year history of a slow‑growing, painless, left scrotal mass. Magnetic resonance imaging identified a mass in the left scrotum with mixed signal intensity; no abnormal signals were identified in the right testicle and retroperitoneal lymph node. An X‑ray of the chest demonstrated no evidence of metastasis. Subsequent to this, a left RIO was performed. Histopathological and immunohistochemical examination confirmed the final diagnosis of embryonal ITRMS. At 21 days post-surgery, an 18F-fluorodeoxyglucose-positron emission tomography-computed tomography (FDG‑PET‑CT) scan identified widespread metastatic lesions in the lungs, local lymph nodes and bones, presenting as increased glucose metabolism nodules. Subsequently, the patient received six sequential cycles of adjunct chemotherapy. The patient is alive with disease in October 2015. The case described is noteworthy as it is an example of ITRMS, in which the patient received successful treatment. However, multidisciplinary treatment may further improve the outcome of the disease.
View Figures

Figure 1

Figure 2

Figure 3

View References

1 

Dagher R and Helman L: Rhabdomyosarcoma: An overview. Oncologist. 4:34–44. 1999.PubMed/NCBI

2 

Liu ZW, Zhang XQ, Hou GL, Zhang ZL, Qin ZK, Han H and Zhou FJ: Primary adult intratesticular rhabdomyosarcoma, Results of the treatment of six cases. Int J Urol. 18:171–174. 2011. View Article : Google Scholar : PubMed/NCBI

3 

Kumar PV, Kazemi H and Khezri A: Testicular embryonal rhabdomyosarcoma diagnosed by fine needle aspiration cytology. Histopathology. Acta Cytol. 38:573–576. 1994.PubMed/NCBI

4 

Banfield GK and Brookstein R: Rhabdomyosarcoma arising in teratoma of the testis. J R Army Med Corps. 141:167–168. 1995. View Article : Google Scholar : PubMed/NCBI

5 

Alexander F: Pure testicular rhabdomyosarcoma. Br J Cancer. 22:498–501. 1968. View Article : Google Scholar : PubMed/NCBI

6 

Nasit JG, Parikh B, Trivedi P and Shah M: Primary intratesticular rhabdomyosarcoma in pediatrics. Indian J Urol. 29:77–79. 2013. View Article : Google Scholar : PubMed/NCBI

7 

Thompson KS, Jensen JD, Bhoopalam N and Reyes CV: Pleural effusion cytology of embryonal rhabdomyosarcoma. Diagn Cytopathol. 16:270–273. 1997. View Article : Google Scholar : PubMed/NCBI

8 

Chung JM, Lim YT and Lee SD: Infantile testicular rhabdomyosarcoma. Urology. 69:1208.e13–1208.e15. 2007. View Article : Google Scholar

9 

Kelly B, Lundon D, Rowaiye B, Daly P and Walsh K: Embryonal rhabdomyosarcoma of the testis. Can Urol Assoc J. 5:E7–E10. 2011.PubMed/NCBI

10 

Terrier-Lacombe MJ, Martinez-Madrigal F, Porta W, Rahal J and Droz JP: Embryonal rhabdomyosarcoma arising in a mature teratoma of the testis, A case report. J Urol. 143:1232–1234. 1990.PubMed/NCBI

11 

Jungling MJ and Culp DA: Case report of embryonal rhabdomyosarcoma of the testis with an 8-year survival. J Urol. 114:313–315. 1975.PubMed/NCBI

12 

Erbay ME, Tarhan F, Barişik NO and Kuyumcuoğlu U: A case of testicular rhabdomyosarcoma. Int Urol Nephrol. 36:73–75. 2004. View Article : Google Scholar : PubMed/NCBI

13 

Singh R, Chandra A and O'Brien TS: Primary intratesticular leiomyosarcoma in a mixed race man A case report. J Clin Pathol. 57:1319–1320. 2004. View Article : Google Scholar : PubMed/NCBI

14 

Ayati M, Izadpanahi MM, Nowroozi MR, Soroush Z, Jamshidian H and Rakhshani N: First case report of bilateral metastatic intratesticular rhabdomyosarcoma. Urology. 75:1485–1487. 2010. View Article : Google Scholar : PubMed/NCBI

15 

Cannon GM Jr, Polsky EG and Bellinger MF: Metastatic intratesticular alveolar rhabdomyosarcoma discovered after induction of systemic chemotherapy. Urology. 69:982.e13–982.e15. 2007. View Article : Google Scholar

16 

Medioni J, Fernandez-Bruno P, Meignin V, Bourrier P, Laurence V, Ramdani M, Dupuy-Grasset M and Cottu P: Testicular metastasis of alveolar rhabdomyosarcoma, Clinical case of a 19-year-old man. Prog Urol. 13:700–702. 2003.(In French). PubMed/NCBI

17 

Bouvier DP, Fox CW Jr, Frishberg DP, Kozakowski M and Cobos E: A solitary testicular relapse of a rhabdomyosarcoma in an adult. Cancer. 65:2611–2614. 1990. View Article : Google Scholar : PubMed/NCBI

18 

Gow KW, Murphy JJ III, Wu JK and Desa DJ: Metastatic testicular rhabdomyosarcoma - a report of two cases. J Pediatr Surg. 38:E1–E3. 2003. View Article : Google Scholar : PubMed/NCBI

19 

Shimamoto K, Tanji N, Ozaw A, Sasaki T, Ikeda T, Iseda T and Yokoyama M: Intrascrotal rhabdomyosarcoma in adult, A case report. Nippon Hinyokika Gakkai Zasshi. 100:545–549. 2009.(In Japanese). PubMed/NCBI

20 

Evens AM and Kostakoglu L: The role of FDG-PET in defining prognosis of Hodgkin lymphoma for early-stage disease. Blood. 124:3356–3364. 2014. View Article : Google Scholar : PubMed/NCBI

21 

Maffione AM, Marzola MC, Capirci C, Colletti PM and Rubello D: Value of (18)F-FDG PET for predicting response to neoadjuvant therapy in rectal cancer, Systematic review and meta-analysis. AJR Am J Roentgenol. 204:1261–1268. 2015. View Article : Google Scholar : PubMed/NCBI

22 

Meyer WH and Spunt SL: Soft tissue sarcomas of childhood. Cancer Treat Rev. 30:269–280. 2004. View Article : Google Scholar : PubMed/NCBI

23 

Sexton WJ, Lance RE, Reyes AO, Pisters PW, Tu SM and Pisters LL: Adult prostate sarcoma, The M. Histopathology. J Urol. 166:521–525. 2001. View Article : Google Scholar : PubMed/NCBI

24 

Spiess PE, Kassouf W, Steinberg JR, Tuziak T, Hernandez M, Tibbs RF, Czerniak B, Kamat AM, Dinney CP and Grossman HB: Review of the M.D. Histopathology. Urol Oncol. 25:38–45. 2007. View Article : Google Scholar : PubMed/NCBI

25 

Stewart LH, Lioe TF and Johnston SR: Thirty-year review of intrascrotal rhabdomyosarcoma. Br J Urol. 68:418–420. 1991. View Article : Google Scholar : PubMed/NCBI

Related Articles

  • Abstract
  • View
  • Download
  • Twitter
Copy and paste a formatted citation
Spandidos Publications style
Yi J, Zhou DA, Huo JR, Wang YH and Ma JA: Primary intratesticular rhabdomyosarcoma: A case report and literature review. Oncol Lett 11: 1016-1020, 2016.
APA
Yi, J., Zhou, D., Huo, J., Wang, Y., & Ma, J. (2016). Primary intratesticular rhabdomyosarcoma: A case report and literature review. Oncology Letters, 11, 1016-1020. https://doi.org/10.3892/ol.2015.3987
MLA
Yi, J., Zhou, D., Huo, J., Wang, Y., Ma, J."Primary intratesticular rhabdomyosarcoma: A case report and literature review". Oncology Letters 11.2 (2016): 1016-1020.
Chicago
Yi, J., Zhou, D., Huo, J., Wang, Y., Ma, J."Primary intratesticular rhabdomyosarcoma: A case report and literature review". Oncology Letters 11, no. 2 (2016): 1016-1020. https://doi.org/10.3892/ol.2015.3987
Copy and paste a formatted citation
x
Spandidos Publications style
Yi J, Zhou DA, Huo JR, Wang YH and Ma JA: Primary intratesticular rhabdomyosarcoma: A case report and literature review. Oncol Lett 11: 1016-1020, 2016.
APA
Yi, J., Zhou, D., Huo, J., Wang, Y., & Ma, J. (2016). Primary intratesticular rhabdomyosarcoma: A case report and literature review. Oncology Letters, 11, 1016-1020. https://doi.org/10.3892/ol.2015.3987
MLA
Yi, J., Zhou, D., Huo, J., Wang, Y., Ma, J."Primary intratesticular rhabdomyosarcoma: A case report and literature review". Oncology Letters 11.2 (2016): 1016-1020.
Chicago
Yi, J., Zhou, D., Huo, J., Wang, Y., Ma, J."Primary intratesticular rhabdomyosarcoma: A case report and literature review". Oncology Letters 11, no. 2 (2016): 1016-1020. https://doi.org/10.3892/ol.2015.3987
Follow us
  • Twitter
  • LinkedIn
  • Facebook
About
  • Spandidos Publications
  • Careers
  • Cookie Policy
  • Privacy Policy
How can we help?
  • Help
  • Live Chat
  • Contact
  • Email to our Support Team