1
|
Parkin DM, Bray F, Ferlay J and Pisani P:
Global cancer statistics, 2002. CA Cancer J Clin. 55:74–108. 2005.
View Article : Google Scholar : PubMed/NCBI
|
2
|
He J, Gu D, Wu X, Reynolds K, Duan X, Yao
C, Wang J, Chen CS, Chen J, Wildman RP, et al: Major causes of
death among men and women in China. N Engl J Med. 353:1124–1134.
2005. View Article : Google Scholar : PubMed/NCBI
|
3
|
Ye QH, Qin LX, Forgues M, He P, Kim JW,
Peng AC, Simon R, Li Y, Robles AI, Chen Y, et al: Predicting
hepatitis B virus-positive metastatic hepatocellular carcinomas
using gene expression profiling and supervised machine learning.
Nat Med. 9:416–423. 2003. View
Article : Google Scholar : PubMed/NCBI
|
4
|
Portolani N, Coniglio A, Ghidoni S,
Giovanelli M, Benetti A, Tiberio GA and Giulini SM: Early and late
recurrence after liver resection for hepatocellular carcinoma,
Prognostic and therapeutic implications. Ann Surg. 243:229–235.
2006. View Article : Google Scholar : PubMed/NCBI
|
5
|
Petersen BE, Bowen WC, Patrene KD, Mars
WM, Sullivan AK, Murase N, Boggs SS, Greenberger JS and Goff JP:
Bone marrow as a potential source of hepatic oval cells. Science.
284:1168–1170. 1999. View Article : Google Scholar : PubMed/NCBI
|
6
|
Jang YY, Collector MI, Baylin SB, Diehl AM
and Sharkis SJ: Hematopoietic stem cells convert into liver cells
within days without fusion. Nat Cell Biol. 6:532–539. 2004.
View Article : Google Scholar : PubMed/NCBI
|
7
|
Alison MR and Lovell MJ: Liver cancer: The
role of stem cells. Cell Prolif. 38:407–421. 2005. View Article : Google Scholar : PubMed/NCBI
|
8
|
Li GC, Ye QH, Xue YH, Sun HJ, Zhou HJ, Ren
N, Jia HL, Shi J, Wu JC, Dai C, et al: Human mesenchymal stem cells
inhibit metastasis of a hepatocellular carcinoma model using the
MHCC97-H cell line. Cancer Sci. 101:2546–2553. 2010. View Article : Google Scholar : PubMed/NCBI
|
9
|
Hanahan D and Weinberg RA: Hallmarks of
cancer: The next generation. Cell. 144:646–674. 2011. View Article : Google Scholar : PubMed/NCBI
|
10
|
Rakesh KJ, Dan GD, Christopher GW,
Dushyant VS, Andrew XZ, Jay SL and Tracy TB: Biomarkers of response
and resistance to antiangiogenic therapy. Nat Rev Clin Oncol.
6:327–338. 2009. View Article : Google Scholar : PubMed/NCBI
|
11
|
Poon RT, Ng IO, Lau C, Yu WC, Yang ZF, Fan
ST and Wong J: Tumor microvessel density as a predictor of
recurrence after resection of hepatocellular carcinoma, A
prospective study. J Clin Oncol. 20:1775–1785. 2002. View Article : Google Scholar : PubMed/NCBI
|
12
|
Qin LX and Tang ZY: Recent progress in
predictive biomarkers for metastatic recurrence of human
hepatocellular carcinoma: A review of the literature. J Cancer Res
Clin Oncol. 130:497–513. 2004. View Article : Google Scholar : PubMed/NCBI
|
13
|
Lyden D, Hattori K, Dias S, Costa C,
Blaikie P, Butros L, Chadburn A, Heissig B, Marks W, Witte L, et
al: Impaired recruitment of bone-marrow-derived endothelial and
hematopoietic precursor cells blocks tumour angiogenesis and
growth. Nat Med. 7:1194–1201. 2001. View Article : Google Scholar : PubMed/NCBI
|
14
|
Reyes M, Dudek A, Jahagirdar B, Koodie L,
Marker PH and Verfaillie CM: Origin of endothelial progenitors in
human postnatal bone marrow. J Clin Invest. 109:337–346. 2002.
View Article : Google Scholar : PubMed/NCBI
|
15
|
Kinnaird T, Stabile E, Burnett MS, Shou M,
Lee CW, Barr S, Fuchs S and Epstein SE: Local delivery of
marrow-derived stromal cells augments collateral perfusion through
paracrine mechanisms. Circulation. 109:1543–1549. 2004. View Article : Google Scholar : PubMed/NCBI
|
16
|
Bellone G, Gramigni C, Vizio B, Mauri FA,
Prati A, Solerio D, Dughera L, Ruffini E, Gasparri G and Camandona
M: Abnormal expression of Endoglin and its receptor complex (TGF-β1
and TGF-β receptor II) as early angiogenic switch indicator in
premalignant lesions of the colon mucosa. Int J Oncol.
37:1153–1165. 2010. View Article : Google Scholar : PubMed/NCBI
|
17
|
Kuo SW, Ke FC, Chang GD, Lee MT and Hwang
JJ: Potential role of follicle-stimulating hormone (FSH) and
transforming growth factor (TGFβ1) in the regulation of ovarian
angiogenesis. J Cell Physiol. 226:1608–1619. 2011. View Article : Google Scholar : PubMed/NCBI
|
18
|
Mazzocca A, Fransvea E, Lavezzari G,
Antonaci S and Giannelli G: Inhibition of transforming growth
factor beta receptor I kinase blocks hepatocellular carcinoma
growth through neo-angiogenesis regulation. Hepatology.
50:1140–1151. 2009. View Article : Google Scholar : PubMed/NCBI
|
19
|
Jiang Y, Jahagirdar BN, Reinhardt RL,
Schwartz RE, Keene CD, Ortiz-Gonzalez XR, Reyes M, Lenvik T, Lund
T, Blackstad M, et al: Pluripotency of mesenchymal stem cells
derived from adult marrow. Nature. 418:41–49. 2002. View Article : Google Scholar : PubMed/NCBI
|
20
|
Li Y, Tang ZY, Ye SL, Liu YK, Chen J, Xue
Q, Chen J, Gao DM and Bao WH: Establishment of cell clones with
different metastatic potential from the metastatic hepatocellular
carcinoma cell line MHCC97. World J Gastroenterol. 7:630–636.
2001.PubMed/NCBI
|
21
|
Li Y, Tang Y, Ye L, Liu B, Liu K, Chen J
and Xue Q: Establishment of a hepatocellular carcinoma cell line
with unique metastatic characteristics through in vivo
selection and screening for metastasis-related genes through cDNA
microarray. J Cancer Res Clin Oncol. 129:43–51. 2003.PubMed/NCBI
|
22
|
Ferdowsian H: Human and animal research
guidelines: A ligning ethical constructs with new scientific
developments. Bioethics. 25:472–478. 2011. View Article : Google Scholar : PubMed/NCBI
|
23
|
Chen ZY, Wei W, Guo ZX, Lin JR, Shi M and
Guo RP: Morphologic classification of microvessels in
hepatocellular carcinoma is associated with the prognosis after
resection. J Gastroenterol Hepatol. 26:866–874. 2011. View Article : Google Scholar : PubMed/NCBI
|
24
|
Sun HC, Tang ZY, Li XM, Zhou YN, Sun BR
and Ma ZC: Microvessel density of hepatocellular carcinoma, Its
relationship with prognosis. J Cancer Res Clin Oncol. 125:419–426.
1999. View Article : Google Scholar : PubMed/NCBI
|
25
|
Gasparini G: Prognostic value of vascular
endothelial growth factor in breast cancer. Oncologist. 5(Suppl 1):
37–44. 2000. View Article : Google Scholar : PubMed/NCBI
|
26
|
Littlepage LE, Egeblad M and Werb Z:
Coevolution of cancer and stromal cellular responses. Cancer Cell.
7:499–500. 2005. View Article : Google Scholar : PubMed/NCBI
|
27
|
Leek RD, Harris AL and Lewis CE: Cytokine
networks in solid human tumors, Regulation of angiogenesis. J
Leukoc Biol. 56:423–435. 1994.PubMed/NCBI
|
28
|
Oft M, Heider KH and Beug H: TGFbeta
signaling is necessary for carcinoma cell invasiveness and
metastasis. Curr Biol. 8:1243–1252. 1998. View Article : Google Scholar : PubMed/NCBI
|
29
|
Iyer S, Wang ZG, Akhtari M, Zhao W and
Seth P: Targeting TGFbeta signaling for cancer therapy. Cancer Biol
Ther. 4:261–266. 2005. View Article : Google Scholar : PubMed/NCBI
|
30
|
Welm AL: TGFβ primes breast tumor cells
for metastasis. Cell. 133:27–28. 2008. View Article : Google Scholar : PubMed/NCBI
|
31
|
Yu Q and Stamenkovic I: Cell
surface-localized matrix metalloproteinase-9 proteolytically
activates TGF-beta and promotes tumor invasion and angiogenesis.
Genes Dev. 14:163–176. 2000.PubMed/NCBI
|
32
|
Derynck R, Akhurst RJ and Balmain A:
TGF-beta signaling in tumor suppression and cancer progression. Nat
Genet. 29:117–129. 2001. View Article : Google Scholar : PubMed/NCBI
|
33
|
Salcedo X, Medina J, Sanz-Cameno P,
García-Buey L, Martín-Vilchez S and Moreno-Otero R: Review article
Angiogenesis soluble factors as liver disease markers. Aliment
Pharmacol Ther. 22:23–30. 2005. View Article : Google Scholar : PubMed/NCBI
|
34
|
Brogi E, Wu T, Namiki A and Isner JM:
Indirect angiogenic cytokines upregulate VEGF and bFGF gene
expression in vascular smooth muscle cells, whereas hypoxia
upregulates VEGF expression only. Circulation. 90:649–652. 1994.
View Article : Google Scholar : PubMed/NCBI
|
35
|
Greenbaum D, Colangelo C, Williams K and
Gerstein M: Comparing protein abundance and mRNA expression levels
on a genomic scale. Genome Biol. 4:1172003. View Article : Google Scholar : PubMed/NCBI
|
36
|
Ferrari G, Pintucci G, Seghezzi G, Hyman
K, Galloway AC and Mignatti P: VEGF, a prosurvival factor, acts in
concert with TGF-beta1 to induce endothelial cell apoptosis. Proc
Natl Acad Sci USA. 103:17260–17265. 2006. View Article : Google Scholar : PubMed/NCBI
|
37
|
Jeon SH, Chae BC, Kim HA, Seo GY, Seo DW,
Chun GT, Kim NS, Yie SW, Byeon WH, Eom SH, et al: Mechanisms
underlying TGF-beta1-induced expression of VEGF and Flk-1 in mouse
macrophages and their implications for angiogenesis. J Leukoc Biol.
81:557–566. 2007. View Article : Google Scholar : PubMed/NCBI
|
38
|
Lee KS, Park SJ, Kim SR, Min KH, Lee KY,
Choe YH, Hong SH, Lee YR, Kim JS, Hong SJ and Lee YC: Inhibition of
VEGF blocks TGF-beta1 production through a PI3K/Akt signalling
pathway. Eur Respir J. 31:523–531. 2008. View Article : Google Scholar : PubMed/NCBI
|
39
|
Ferrari G, Cook BD, Terushkin V, Pintucci
G and Mignatti P: Transforming growth factor-beta 1 (TGF-beta1)
induces angiogenesis through vascular endothelial growth factor
(VEGF)-mediated apoptosis. J Cell Physiol. 219:449–458. 2009.
View Article : Google Scholar : PubMed/NCBI
|