Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Oncology Letters
      • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Biomedical Reports
      • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • Information for Authors
    • Information for Reviewers
    • Information for Librarians
    • Information for Advertisers
    • Conferences
  • Language Editing
Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • For Authors
    • For Reviewers
    • For Librarians
    • For Advertisers
    • Conferences
  • Language Editing
Login Register Submit
  • This site uses cookies
  • You can change your cookie settings at any time by following the instructions in our Cookie Policy. To find out more, you may read our Privacy Policy.

    I agree
Search articles by DOI, keyword, author or affiliation
Search
Advanced Search
presentation
Oncology Letters
Join Editorial Board Propose a Special Issue
Print ISSN: 1792-1074 Online ISSN: 1792-1082
Journal Cover
February-2016 Volume 11 Issue 2

Full Size Image

Sign up for eToc alerts
Recommend to Library

Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

Journal Cover
February-2016 Volume 11 Issue 2

Full Size Image

Sign up for eToc alerts
Recommend to Library

  • Article
  • Citations
    • Cite This Article
    • Download Citation
    • Create Citation Alert
    • Remove Citation Alert
    • Cited By
  • Similar Articles
    • Related Articles (in Spandidos Publications)
    • Similar Articles (Google Scholar)
    • Similar Articles (PubMed)
  • Download PDF
  • Download XML
  • View XML
Article Open Access

Genomic mapping of pathways in endometrial adenocarcinoma and a gastrointestinal stromal tumor located in Meckel's diverticulum

  • Authors:
    • Monika Englert‑Golon
    • Bartlomiej Budny
    • Bartosz Burchardt
    • Elzbieta Wrotkowska
    • Katarzyna Ziemnicka
    • Marek Ruchała
    • Stefan Sajdak
  • View Affiliations / Copyright

    Affiliations: Surgical Gynecology Clinic of the Gynecological and Obstetrics Clinical Hospital, Poznan University of Medical Sciences, 60‑535 Poznan, Poland, Department of Endocrinology, Metabolism and Internal Diseases, Poznan University of Medical Sciences, 60‑535 Poznan, Poland
    Copyright: © Englert‑Golon et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Pages: 1007-1015
    |
    Published online on: December 4, 2015
       https://doi.org/10.3892/ol.2015.4004
  • Expand metrics +
Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )
Metrics: Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )
Cited By (CrossRef): 0 citations Loading Articles...

This article is mentioned in:



Abstract

The present study reports the case of a 71-year-old female patient diagnosed with endometrial adenocarcinoma, which was confirmed by histopathology. In the course of performing an elective hysterectomy with adnexa removal, a solid tumor located in Meckel's diverticulum (MD) was identified and excised. Due to the unique nature of the lesion, the tumor tissue underwent broad mapping of any genomic alterations once the histopathological examination was completed. The genetic testing was conducted using a high‑resolution microarray and resulted in the identification of 45 genomic abnormalities, including 4 chromosomal aneuploidies. Within those regions, alterations of 87 known cancer genes were assigned. The involvement of v‑kit Hardy‑Zuckerman 4 feline sarcoma viral oncogene homolog gene alteration was noted to be a key player for triggering gastrointestinal stromal tumor transformation for this unusual case. A total of 12 genes, showing mutual interaction in different cancer types or involved in diverse cellular processes, were identified. These reported data may shed light on the carcinogenesis of a rare MD tumor.
View Figures

Figure 1

Figure 2

Figure 3

Figure 4

View References

1 

Sircar K, Hewlett BR, Huizinga JD, Chorneyko K, Berezin I and Riddell RH: Interstitial cells of Cajal as precursors of gastrointestinal stromal tumors. Am J Surg Pathol. 23:377–389. 1999. View Article : Google Scholar : PubMed/NCBI

2 

Chan JK: Mesenchymal tumors of the gastrointestinal tract: A paradise for acronyms (STUMP, GIST GANT, and now GIPACT), implication of c-kit in genesis, and yet another of the many emerging roles of the interstitial cell of Cajal in the pathogenesis of gastrointestinal diseases? Adv Anat Pathol. 6:19–40. 1999. View Article : Google Scholar : PubMed/NCBI

3 

Rutkowski P, Debiec-Rychter M and Ruka W: Gastrointestinal stromal tumors, Key to diagnosis and choice of therapy. Mol Diagn Ther. 12:131–143. 2008. View Article : Google Scholar : PubMed/NCBI

4 

Rutkowski P, Wozniak A, Dębiec-Rychter M, Kąkol M, Dziewirski W, Zdzienicki M, Ptaszynski K, Jurkowska M, Limon J and Siedlecki JA: Clinical utility of the new American Joint Committee on Cancer staging system for gastrointestinal stromal tumors, Current overall survival after primary tumor resection. Cancer. 117:4916–4924. 2011. View Article : Google Scholar : PubMed/NCBI

5 

Corless CL, Fletcher JA and Heinrich MC: Biology of gastrointestinal stromal tumors. J Clin Oncol. 22:3813–3825. 2004. View Article : Google Scholar : PubMed/NCBI

6 

Miettinen M, Sarlomo-Rikala M and Lasota J: Gastrointestinal stromal tumors, Recent advances in understanding of their biology. Hum Pathol. 30:1213–1220. 1999. View Article : Google Scholar : PubMed/NCBI

7 

Roberts PJ and Eisenberg B: Clinical presentation of gastrointestinal stromal tumors and treatment of operable disease. Eur J Cancer. 38((Suppl 5)): S37–S38. 2002. View Article : Google Scholar : PubMed/NCBI

8 

Neuhaus SJ, Clark MA, Hayes AJ, Thomas JM and Judson I: Surgery for gastrointestinal stromal tumour in the post-imatinib era. ANZ J Surg. 75:165–172. 2005. View Article : Google Scholar : PubMed/NCBI

9 

Duensing A, Heinrich MC, Fletcher CD and Fletcher JA: Biology of gastrointestinal stromal tumors, KIT mutations and beyond. Cancer Invest. 22:106–116. 2004. View Article : Google Scholar : PubMed/NCBI

10 

Heinrich MC, Rubin BP, Longley BJ and Fletcher JA: Biology and genetic aspects of gastrointestinal stromal tumors, KIT activation and cytogenetic alterations. Hum Pathol. 33:484–495. 2002. View Article : Google Scholar : PubMed/NCBI

11 

Huizinga JD, Thuneberg L, Klüppel M, Malysz J, Mikkelsen HB and Bernstein A: W/kit gene required for interstitial cells of Cajal and for intestinal pacemaker activity. Nature. 373:347–349. 1995. View Article : Google Scholar : PubMed/NCBI

12 

Nannini M, Astolfi A, Urbini M, Indio V, Santini D, Heinrich MC, Corless CL, Ceccarelli C, Saponara M, Mandrioli A, et al: Integrated genomic study of quadruple-WT GIST (KIT/PDGFRA/SDH/RAS pathway wild-type GIST). BMC Cancer. 14:6852014. View Article : Google Scholar : PubMed/NCBI

13 

Pantaleo MA, Nannini M, Corless CL and Heinrich MC: Quadruple wild-type (WT) GIST, Defining the subset of GIST that lacks abnormalities of KIT, PDGFRA, SDH, or RAS signaling pathways. Cancer Med. 4:101–103. 2014. View Article : Google Scholar : PubMed/NCBI

14 

Heinrich MC, Griffith DJ, Druker BJ, Wait CL, Ott KA and Zigler AJ: Inhibition of c-kit receptor tyrosine kinase activity by STI 571, a selective tyrosine kinase inhibitor. Blood. 96:925–932. 2000.PubMed/NCBI

15 

Chandramohan K, Agarwal M, Gurjar G, Gatti RC, Patel MH, Trivedi P and Kothari KC: Gastrointestinal stromal tumour in Meckel's diverticulum. World J Surg Oncol. 5:502007. View Article : Google Scholar : PubMed/NCBI

16 

Khoury MG: 2nd andA ulicino MR: Gastrointestinal stromal tumor (GIST) presenting in a Meckel's diverticulum. Abdom Imaging. 32:78–80. 2007. View Article : Google Scholar : PubMed/NCBI

17 

Kosmidis C, Efthimiadis C, Levva S, Anthimidis G, Baka S, Grigoriou M, Tzeveleki I, Masmanidou M, Zaramboukas T and Basdanis G: Synchronous colorectal adenocarcinoma and gastrointestinal stromal tumor in Meckel's diverticulum; an unusual association. World J Surg Oncol. 7:332009. View Article : Google Scholar : PubMed/NCBI

18 

Thirunavukarasu P, Sathaiah M, Sukumar S, Bartels CJ, Zeh H III, Lee KK and Bartlett DL: Meckel's diverticulum - a high-risk region for malignancy in the ileum. Insights from a population-based epidemiological study and implications in surgical management. Ann Surg. 253:223–230. 2011. View Article : Google Scholar : PubMed/NCBI

19 

Gillio-Tos A, De Marco L, Fiano V, Garcia-Bragado F, Dikshit R, Boffetta P and Merletti F: Efficient DNA extraction from 25-year-old paraffin-embedded tissues, Study of 365 samples. Pathology. 39:345–348. 2007. View Article : Google Scholar : PubMed/NCBI

20 

Forbes SA, Bindal N, Bamford S, Cole C, Kok CY, Beare D, Jia M, Shepherd R, Leung K, Menzies A, et al: COSMIC: Mining complete cancer genomes in the Catalogue of Somatic Mutations in Cancer. Nucleic Acids Res. 39(Database): D945–D950. 2011. View Article : Google Scholar : PubMed/NCBI

21 

Futreal PA, Coin L, Marshall M, Down T, Hubbard T, Wooster R, Rahman N and Stratton MR: A census of human cancer genes. Nat Rev Cancer. 4:177–183. 2004. View Article : Google Scholar : PubMed/NCBI

22 

de Castro Pérez I, de Cárcer G and Malumbres M: A census of mitotic cancer genes: New insights into tumor cell biology and cancer therapy. Carcinogenesis. 28:899–912. 2007. View Article : Google Scholar : PubMed/NCBI

23 

Santarius T, Shipley J, Brewer D, Stratton MR and Cooper CS: A census of amplified and overexpressed human cancer genes. Nat Rev Cancer. 10:59–64. 2010. View Article : Google Scholar : PubMed/NCBI

24 

Altermann E and Klaenhammer TR: PathwayVoyager: Pathway mapping using the Kyoto Encyclopedia of Genes and Genomes (KEGG) database. BMC Genomics. 6:602005. View Article : Google Scholar : PubMed/NCBI

25 

Franceschini A, Szklarczyk D, Frankild S, Kuhn M, Simonovic M, Roth A, Lin J, Minguez P, Bork P, von Mering C, et al: STRING v9.1: Protein-protein interaction networks, with increased coverage and integration. Nucleic Acids Res. 41(D1): D808–D815. 2013. View Article : Google Scholar : PubMed/NCBI

26 

Nilsson B, Bümming P, Meis-Kindblom JM, Odén A, Dortok A, Gustavsson B, Sablinska K and Kindblom LG: Gastrointestinal stromal tumors, The incidence, prevalence, clinical course, and prognostication in the preimatinib mesylate era - a population-based study in western Sweden. Cancer. 103:821–829. 2005. View Article : Google Scholar : PubMed/NCBI

27 

Dematteo RP, Heinrich MC, El-Rifai WM and Demetri G: Clinical management of gastrointestinal stromal tumors, Before and after STI-571. Hum Pathol. 33:466–477. 2002. View Article : Google Scholar : PubMed/NCBI

28 

Tosoni A, Nicolardi L and Brandes AA: Current clinical management of gastrointestinal stromal tumors. Expert Rev Anticancer Ther. 4:595–605. 2004. View Article : Google Scholar : PubMed/NCBI

29 

Ruka W, Rutkowski P, Nowecki Z, Nasierowska-Guttmejer A and Debiec-Rychter M: Other malignant neoplasms in patients with gastrointestinal stromal tumors (GIST). Med Sci Monit. 10:LE13–LE14. 2004.PubMed/NCBI

30 

Rutkowski P, Nowecki ZI, Michej W, Debiec-Rychter M, Woźniak A, Limon J, Siedlecki J, Grzesiakowska U, Kakol M, Osuch C, et al: Risk criteria and prognostic factors for predicting recurrences after resection of primary gastrointestinal stromal tumor. Ann Surg Oncol. 14:2018–2027. 2007. View Article : Google Scholar : PubMed/NCBI

31 

Hirota S, Isozaki K, Moriyama Y, Hashimoto K, Nishida T, Ishiguro S, Kawano K, Hanada M, Kurata A, Takeda M, et al: Gain-of-function mutations of c-kit in human gastrointestinal stromal tumors. Science. 279:577–580. 1998. View Article : Google Scholar : PubMed/NCBI

32 

Chompret A, Kannengiesser C, Barrois M, Terrier P, Dahan P, Tursz T, Lenoir GM and Bressac-De Paillerets B: PDGFRA germline mutation in a family with multiple cases of gastrointestinal stromal tumor. Gastroenterology. 126:318–321. 2004. View Article : Google Scholar : PubMed/NCBI

33 

Kwon JE, Kang HJ, Kim SH, Lee YC, Hyung WJ, Noh SH, Kim NK and Kim H: Pathological characteristics of gastrointestinal stromal tumours with PDGFRA mutations. Pathology. 41:544–554. 2009. View Article : Google Scholar : PubMed/NCBI

34 

Schaefer IM, Ströbel P, Cameron S, Beham A, Otto C, Schildhaus HU and Agaimy A: Rhabdoid morphology in gastrointestinal stromal tumours (GISTs) is associated with PDGFRA mutations but does not imply aggressive behaviour. Histopathology. 64:421–430. 2014. View Article : Google Scholar : PubMed/NCBI

35 

Gunawan B, Bergmann F, Höer J, Langer C, Schumpelick V, Becker H and Füzesi L: Biological and clinical significance of cytogenetic abnormalities in low-risk and high-risk gastrointestinal stromal tumors. Hum Pathol. 33:316–321. 2002. View Article : Google Scholar : PubMed/NCBI

36 

Schoppmann SF, Vinatzer U, Popitsch N, Mittlböck M, Liebmann-Reindl S, Jomrich G, Streubel B and Birner P: Novel clinically relevant genes in gastrointestinal stromal tumors identified by exome sequencing. Clin Cancer Res. 19:5329–5339. 2013. View Article : Google Scholar : PubMed/NCBI

37 

Wozniak A, Sciot R, Guillou L, Pauwels P, Wasag B, Stul M, Vermeesch JR, Vandenberghe P, Limon J and Debiec-Rychter M: Array CGH analysis in primary gastrointestinal stromal tumors Cytogenetic profile correlates with anatomic site and tumor aggressiveness, irrespective of mutational status. Genes Chromosomes Cancer. 46:261–276. 2007. View Article : Google Scholar : PubMed/NCBI

38 

Astolfi A, Nannini M, Pantaleo MA, Di Battista M, Heinrich MC, Santini D, Catena F, Corless CL, Maleddu A, Saponara M, et al: A molecular portrait of gastrointestinal stromal tumors: An integrative analysis of gene expression profiling and high-resolution genomic copy number. Lab Invest. 90:1285–1294. 2010. View Article : Google Scholar : PubMed/NCBI

39 

Lagarde P, Pérot G, Kauffmann A, Brulard C, Dapremont V, Hostein I, Neuville A, Wozniak A, Sciot R, Schöffski P, et al: Mitotic checkpoints and chromosome instability are strong predictors of clinical outcome in gastrointestinal stromal tumors. Clin Cancer Res. 18:826–838. 2012. View Article : Google Scholar : PubMed/NCBI

40 

Liu CH, Chen TC, Chau GY, Jan YH, Chen CH, Hsu CN, Lin KT, Juang YL, Lu PJ, Cheng HC, et al: Analysis of protein-protein interactions in cross-talk pathways reveals CRKL protein as a novel prognostic marker in hepatocellular carcinoma. Mol Cell Proteomics. 12:1335–1349. 2013. View Article : Google Scholar : PubMed/NCBI

Related Articles

  • Abstract
  • View
  • Download
  • Twitter
Copy and paste a formatted citation
Spandidos Publications style
Englert‑Golon M, Budny B, Burchardt B, Wrotkowska E, Ziemnicka K, Ruchała M and Sajdak S: Genomic mapping of pathways in endometrial adenocarcinoma and a gastrointestinal stromal tumor located in Meckel's diverticulum. Oncol Lett 11: 1007-1015, 2016.
APA
Englert‑Golon, M., Budny, B., Burchardt, B., Wrotkowska, E., Ziemnicka, K., Ruchała, M., & Sajdak, S. (2016). Genomic mapping of pathways in endometrial adenocarcinoma and a gastrointestinal stromal tumor located in Meckel's diverticulum. Oncology Letters, 11, 1007-1015. https://doi.org/10.3892/ol.2015.4004
MLA
Englert‑Golon, M., Budny, B., Burchardt, B., Wrotkowska, E., Ziemnicka, K., Ruchała, M., Sajdak, S."Genomic mapping of pathways in endometrial adenocarcinoma and a gastrointestinal stromal tumor located in Meckel's diverticulum". Oncology Letters 11.2 (2016): 1007-1015.
Chicago
Englert‑Golon, M., Budny, B., Burchardt, B., Wrotkowska, E., Ziemnicka, K., Ruchała, M., Sajdak, S."Genomic mapping of pathways in endometrial adenocarcinoma and a gastrointestinal stromal tumor located in Meckel's diverticulum". Oncology Letters 11, no. 2 (2016): 1007-1015. https://doi.org/10.3892/ol.2015.4004
Copy and paste a formatted citation
x
Spandidos Publications style
Englert‑Golon M, Budny B, Burchardt B, Wrotkowska E, Ziemnicka K, Ruchała M and Sajdak S: Genomic mapping of pathways in endometrial adenocarcinoma and a gastrointestinal stromal tumor located in Meckel's diverticulum. Oncol Lett 11: 1007-1015, 2016.
APA
Englert‑Golon, M., Budny, B., Burchardt, B., Wrotkowska, E., Ziemnicka, K., Ruchała, M., & Sajdak, S. (2016). Genomic mapping of pathways in endometrial adenocarcinoma and a gastrointestinal stromal tumor located in Meckel's diverticulum. Oncology Letters, 11, 1007-1015. https://doi.org/10.3892/ol.2015.4004
MLA
Englert‑Golon, M., Budny, B., Burchardt, B., Wrotkowska, E., Ziemnicka, K., Ruchała, M., Sajdak, S."Genomic mapping of pathways in endometrial adenocarcinoma and a gastrointestinal stromal tumor located in Meckel's diverticulum". Oncology Letters 11.2 (2016): 1007-1015.
Chicago
Englert‑Golon, M., Budny, B., Burchardt, B., Wrotkowska, E., Ziemnicka, K., Ruchała, M., Sajdak, S."Genomic mapping of pathways in endometrial adenocarcinoma and a gastrointestinal stromal tumor located in Meckel's diverticulum". Oncology Letters 11, no. 2 (2016): 1007-1015. https://doi.org/10.3892/ol.2015.4004
Follow us
  • Twitter
  • LinkedIn
  • Facebook
About
  • Spandidos Publications
  • Careers
  • Cookie Policy
  • Privacy Policy
How can we help?
  • Help
  • Live Chat
  • Contact
  • Email to our Support Team