Ovarian involvement of a desmoplastic small round cell tumor of unknown primary origin with lymph node and lung metastases: A case report

Xie,Yu‑Ping; Shen,Yang‑Mei

doi:10.3892/ol.2015.4012

Ovarian involvement of a desmoplastic small round cell tumor of unknown primary origin with lymph node and lung metastases: A case report

Authors:
- Yu‑Ping Xie
- Yang‑Mei Shen
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Affiliations: Department of Oncology, Chengdu First People's Hospital, Chengdu, Sichuan 610061, P.R. China, Department of Pathology, West China Second University Hospital, Sichuan University, Chengdu, Sichuan 610041, P.R. China
Published online on: December 8, 2015 https://doi.org/10.3892/ol.2015.4012
Pages: 1125-1129

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Abstract

Desmoplastic small round cell tumors (DSRCTs) were initially characterized as exhibiting divergent differentiation and were extremely aggressive, belonging to the family of ‘small round blue cell tumors’. Due to a male predominance, to date, only 15 cases in women have been reported in the English literature. The present study describes a case of DSRCT in a young woman who initially presented with ovarian masses accompanied with lymph node and lung metastases. A correct diagnosis was reached by combining the hematoxylin and eosin, and immunohistochemical staining results. Following surgery, the patient underwent the chemotherapy and, 3 months later, is in a good condition. The study also provides an overview of this uncommon disease.

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