Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Oncology Letters
      • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Biomedical Reports
      • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • Information for Authors
    • Information for Reviewers
    • Information for Librarians
    • Information for Advertisers
    • Conferences
  • Language Editing
Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • For Authors
    • For Reviewers
    • For Librarians
    • For Advertisers
    • Conferences
  • Language Editing
Login Register Submit
  • This site uses cookies
  • You can change your cookie settings at any time by following the instructions in our Cookie Policy. To find out more, you may read our Privacy Policy.

    I agree
Search articles by DOI, keyword, author or affiliation
Search
Advanced Search
presentation
Oncology Letters
Join Editorial Board Propose a Special Issue
Print ISSN: 1792-1074 Online ISSN: 1792-1082
Journal Cover
February-2016 Volume 11 Issue 2

Full Size Image

Sign up for eToc alerts
Recommend to Library

Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

Journal Cover
February-2016 Volume 11 Issue 2

Full Size Image

Sign up for eToc alerts
Recommend to Library

  • Article
  • Citations
    • Cite This Article
    • Download Citation
    • Create Citation Alert
    • Remove Citation Alert
    • Cited By
  • Similar Articles
    • Related Articles (in Spandidos Publications)
    • Similar Articles (Google Scholar)
    • Similar Articles (PubMed)
  • Download PDF
  • Download XML
  • View XML
Article

Clinical value of prenatal echocardiographic examination in the diagnosis of fetal cardiac tumors

  • Authors:
    • Qin Yu
    • Wenhua Zeng
    • Aiyun Zhou
    • Wan Zhu
    • Juan Liu
  • View Affiliations / Copyright

    Affiliations: Department of Ultrasonic Diagnosis, The First Affiliated Hospital of Nanchang University, Nanchang, Jiangxi 330006, P.R. China
  • Pages: 1555-1559
    |
    Published online on: December 28, 2015
       https://doi.org/10.3892/ol.2015.4061
  • Expand metrics +
Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )
Metrics: Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )
Cited By (CrossRef): 0 citations Loading Articles...

This article is mentioned in:



Abstract

The aim of the present study was to explore the clinical value of prenatal echocardiographic examination in the diagnosis of fetal cardiac tumors. In total, the cases of 8 fetuses with fetal cardiac tumors, which were identified by prenatal ultrasound examination in The First Affiliated Hospital of Nanchang University between January 2012 and January 2014, were retrospectively analyzed. The size, shape, location, activity and hemodynamic changes of the lesions were described in detail, and the patients were followed up. Out of the 8 identified cases of fetal cardiac tumors, 2 fetuses contained tumors only in the left ventricular cavity and 6 fetuses contained tumors of the left and right ventricular cavities, interventricular septum and apex of the heart. Overall, 5 of the 8 female patients requested termination of the pregnancy and labor was induced. The fetuses were pathologically confirmed to possess rhabdomyoma. In addition, 1 patient was followed‑up for 5 weeks, and the tumor in the fetal heart cavity was found to have enlarged and developed in multiple regions when follow‑up was performed. The patient then requested termination of the pregnancy and labor was induced. The fetus was pathologically confirmed to possess rhabdomyoma. The remaining 2 patients insisted on continuation of the pregnancy and the fetuses were followed up during gestation and subsequent to birth by echocardiographic examination. Prenatal echocardiography may precisely position and diagnose occupying lesions of the fetal heart, which is of considerable value in clinical decision making and instruction for treatment.
View Figures

Figure 1

Figure 2

View References

1 

Silverman N: Primary cardiac tumors. Ann Surg. 191:127–138. 1980. View Article : Google Scholar : PubMed/NCBI

2 

Smythe JF, Dyck JD, Smallhorn JF and Freedom RM: Natural history of cardiac rhabdomyoma in infancy and childhood. Am J Cardiol. 66:1247–1249. 1990. View Article : Google Scholar : PubMed/NCBI

3 

Stellingwerff GC, Hess J and Bogers AJ: Left ventricular rhabdomyoma. A case report. J Cardiovas Surg (Torino). 40:131–133. 1999.

4 

DeVore GR, Hakim S, Kleinman CS and Hobbins JC: The in utero diagnosis of an interventricular septal cardiac rhabdomyoma by means of real-time-directed, M-mode echocardiography. Am J Obstet Gynecol. 143:967–969. 1982.PubMed/NCBI

5 

DeVore GR: Assessing fetal cardiac ventricular function. Semin Fetal Neonatal Med. 10:515–541. 2005. View Article : Google Scholar : PubMed/NCBI

6 

Van der Hauwaert LG: Cardiac tumors in infancy and childhood. Br Heart J. 33:125–132. 1971. View Article : Google Scholar : PubMed/NCBI

7 

Björkhem G, Lundström NR and Lingman G: Intracardiac rhabdomyomas in neonates: Report of three cases. Acta Paediatr. 81:712–715. 1992. View Article : Google Scholar : PubMed/NCBI

8 

Hamner LH III, Kaye MF and Weingold AB: Difficulty of fetal monitoring in a fetus with intracardiac tumors. Obstet Gynecol. 73:477–481. 1989.PubMed/NCBI

9 

Matsui M and Gardiner H: Current aspects of fetal cardiovascular function. Fetal Matern Med Rev. 19:61–84. 2008. View Article : Google Scholar

10 

Van Mieghem T, DeKoninck P, Steenhaut P and Deprest P: Methods for prenatal assessment of fetal cardiac function. Prenat Diagn. 29:1193–1203. 2009. View Article : Google Scholar : PubMed/NCBI

11 

Hornberger LK: Role of quantitative assessment in fetal echocardiography. Ultrasound Obstet Gynecol. 35:4–6. 2010. View Article : Google Scholar : PubMed/NCBI

12 

World Medical Association: WMA Declaration of Helsinki - Ethical principles for medical research involving human subjects. http://www.chcuk.co.uk/pdf/Declaration_of_Helsinki_2008_Version.pdfAccessed. October 20–2014

13 

Schmaltz AA and Apitz J: Primary heart tumors in infancy and childhood: Report of four cases and review of literature. Cardiology. 67:12–22. 1981. View Article : Google Scholar : PubMed/NCBI

14 

Jentarra GM, Rice SG, Olfers S, Saffen D and Narayanan V: Evidence for population variation in TSC1 and TSC2 gene expression. BMC Med Genet. 12:292011. View Article : Google Scholar : PubMed/NCBI

15 

McAllister HA Jr: Primary tumors of the heart and pericardium. Pathol Annu. 14:325–355. 1979.PubMed/NCBI

16 

Foster ED, Spooner EW, Farina MA, Shaher RM and Alley RD: Cardiac rhabdomyoma in the neonate: Surgical management. Ann Thorac Surg. 37:249–253. 1984. View Article : Google Scholar : PubMed/NCBI

17 

Roach ES, Smith M, Huttenlocher P, Bhat M, Alcorn D and Hawley L: Diagnostic criteria: Tuberous sclerosis complex. Report of the Diagnostic Criteria Committee of the National Tuberous Sclerosis Association. J Clin Neurol. 7:221–224. 1992.

18 

Mühler EG, Kienast W, Turniski-Harder V and von Bernuth G: Arrhythmias in infants and children with primary cardiac tumours. Eur Heart J. 15:915–921. 1994.PubMed/NCBI

19 

Jóźwiak S, Kotulska K, Kasprzyk-Obara J, Domańska-Pakieła D, Tomyn-Drabik M, Roberts P and Kwiatkowski D: Clinical and genotype studies of cardiac tumors in 154 patients with tuberous sclerosis complex. Pediatrics. 118:e1146–e1151. 2006. View Article : Google Scholar : PubMed/NCBI

20 

Chen CP, Su YN, Hung CC, Shih JC and Wang W: Novel mutation in the TSC2 gene associated with prenatally diagnosed cardiac rhabdomyomas and cerebral tuberous sclerosis. J Formos Med Assoc. 105:599–603. 2006. View Article : Google Scholar : PubMed/NCBI

21 

Dal Prato L, Borini A, Coticchio G, Cattoli M and Flamigni P: Half-dose depot triptorelin in pituitary suppression for multiple ovarian stimulation in assisted reproduction technology: A randomized study. Hum Reprod. 19:2200–2205. 2004. View Article : Google Scholar : PubMed/NCBI

22 

Yim SF, Lok IH, Cheung LP, Briton-Jones CM, Chiu TT and Haines CJ: Dose-finding study for the use of long-acting gongadotrophin-releasing hormone analogues prior to ovarian stimulation for IVF. Hum Reprod. 16:492–494. 2001. View Article : Google Scholar : PubMed/NCBI

23 

Sonigo P, Elmaleh A, Fermont L, Delezoíde AL, Mirlesse V and Brunelle F: Prenatal MRI diagnosis of fetal cerebral tuberous sclerosis. Pediatr Radiol. 26:1–4. 1996. View Article : Google Scholar : PubMed/NCBI

24 

Gresser CD, Shime J, Rakowski H, Smallhorn JF, Hui A and Berg JJ: Fetal cardiac tumor: A prenatal cardiographic marker for tuberous sclerosis. Am J Obstet Gynecol. 156:689–690. 1987. View Article : Google Scholar : PubMed/NCBI

25 

Holley DG, Martin GR, Brenner JI, Fyfe DA, Huhta JC, Kleinman CS, Ritter SB and Silverman NH: Diagnosis and management of fetal tumors. A multicenter experience and review of published reports. J Am Coll Cardiol. 26:516–520. 1995. View Article : Google Scholar : PubMed/NCBI

26 

Bertolini P, Meisner H, Paek SU and Sebening F: Special considerations on primary cardiac tumors in infancy and childhood. Thorac Cardiovasc Surg. 38(Suppl 2): 164–167. 1990. View Article : Google Scholar : PubMed/NCBI

Related Articles

  • Abstract
  • View
  • Download
  • Twitter
Copy and paste a formatted citation
Spandidos Publications style
Yu Q, Zeng W, Zhou A, Zhu W and Liu J: Clinical value of prenatal echocardiographic examination in the diagnosis of fetal cardiac tumors. Oncol Lett 11: 1555-1559, 2016.
APA
Yu, Q., Zeng, W., Zhou, A., Zhu, W., & Liu, J. (2016). Clinical value of prenatal echocardiographic examination in the diagnosis of fetal cardiac tumors. Oncology Letters, 11, 1555-1559. https://doi.org/10.3892/ol.2015.4061
MLA
Yu, Q., Zeng, W., Zhou, A., Zhu, W., Liu, J."Clinical value of prenatal echocardiographic examination in the diagnosis of fetal cardiac tumors". Oncology Letters 11.2 (2016): 1555-1559.
Chicago
Yu, Q., Zeng, W., Zhou, A., Zhu, W., Liu, J."Clinical value of prenatal echocardiographic examination in the diagnosis of fetal cardiac tumors". Oncology Letters 11, no. 2 (2016): 1555-1559. https://doi.org/10.3892/ol.2015.4061
Copy and paste a formatted citation
x
Spandidos Publications style
Yu Q, Zeng W, Zhou A, Zhu W and Liu J: Clinical value of prenatal echocardiographic examination in the diagnosis of fetal cardiac tumors. Oncol Lett 11: 1555-1559, 2016.
APA
Yu, Q., Zeng, W., Zhou, A., Zhu, W., & Liu, J. (2016). Clinical value of prenatal echocardiographic examination in the diagnosis of fetal cardiac tumors. Oncology Letters, 11, 1555-1559. https://doi.org/10.3892/ol.2015.4061
MLA
Yu, Q., Zeng, W., Zhou, A., Zhu, W., Liu, J."Clinical value of prenatal echocardiographic examination in the diagnosis of fetal cardiac tumors". Oncology Letters 11.2 (2016): 1555-1559.
Chicago
Yu, Q., Zeng, W., Zhou, A., Zhu, W., Liu, J."Clinical value of prenatal echocardiographic examination in the diagnosis of fetal cardiac tumors". Oncology Letters 11, no. 2 (2016): 1555-1559. https://doi.org/10.3892/ol.2015.4061
Follow us
  • Twitter
  • LinkedIn
  • Facebook
About
  • Spandidos Publications
  • Careers
  • Cookie Policy
  • Privacy Policy
How can we help?
  • Help
  • Live Chat
  • Contact
  • Email to our Support Team