Secondary B-cell lymphoma diagnosed by fine-needle aspiration cytology and flow cytometry following penile carcinoma: A case report

  • Authors:
    • Huan Wang
    • Lian‑Nv Qiu
    • Mao Wu
    • Wan‑Yuan Chen
    • Li‑Gang Ren
    • Xiang‑Lei He
    • Yong‑Lie Zhou
  • View Affiliations

  • Published online on: February 25, 2016     https://doi.org/10.3892/ol.2016.4279
  • Pages: 2449-2452
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Abstract

The number of studies reporting lymphoma as a secondary tumor has gradually increased. However, few studies have reported that occurrence of lymphoma as a secondary tumor following treatment for penile carcinoma, particularly cases in which the lymphoma was diagnosed by fine‑needle aspiration cytology and flow cytometry. The present study reports the case of a 62‑year‑old male patient who was troubled with frequent urination and repeated chest tightness for 5 years. The diagnosis upon admission was penile carcinoma. Two months subsequent to the tumor removal surgery, enlarged lymph nodes were extracted from the patient using fine‑needle biopsy, to be analyzed using light microscopy and flow cytometry. Smear results indicated a large number of abnormal cells scattered in the right axillary lymph node. Flow cytometry immunophenotyping of fine‑needle aspiration samples indicated the increased expression of cluster of differentiation (CD)79a, CD19, CD20, CD38, κ chain and human leukocyte antigen‑DR, which supported a diagnosis of B‑cell lymphoma. Thus, the patient was diagnosed with B‑cell lymphoma based on the results of the fine‑needle aspiration biopsy and flow cytometry. The method of diagnosis and causes of therapy‑related leukemia are discussed in the present report.
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April-2016
Volume 11 Issue 4

Print ISSN: 1792-1074
Online ISSN:1792-1082

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Spandidos Publications style
Wang H, Qiu LN, Wu M, Chen WY, Ren LG, He XL and Zhou YL: Secondary B-cell lymphoma diagnosed by fine-needle aspiration cytology and flow cytometry following penile carcinoma: A case report. Oncol Lett 11: 2449-2452, 2016
APA
Wang, H., Qiu, L., Wu, M., Chen, W., Ren, L., He, X., & Zhou, Y. (2016). Secondary B-cell lymphoma diagnosed by fine-needle aspiration cytology and flow cytometry following penile carcinoma: A case report. Oncology Letters, 11, 2449-2452. https://doi.org/10.3892/ol.2016.4279
MLA
Wang, H., Qiu, L., Wu, M., Chen, W., Ren, L., He, X., Zhou, Y."Secondary B-cell lymphoma diagnosed by fine-needle aspiration cytology and flow cytometry following penile carcinoma: A case report". Oncology Letters 11.4 (2016): 2449-2452.
Chicago
Wang, H., Qiu, L., Wu, M., Chen, W., Ren, L., He, X., Zhou, Y."Secondary B-cell lymphoma diagnosed by fine-needle aspiration cytology and flow cytometry following penile carcinoma: A case report". Oncology Letters 11, no. 4 (2016): 2449-2452. https://doi.org/10.3892/ol.2016.4279