Secondary B-cell lymphoma diagnosed by fine-needle aspiration cytology and flow cytometry following penile carcinoma: A case report

Wang,Huan; Qiu,Lian‑Nv; Wu,Mao; Chen,Wan‑Yuan; Ren,Li‑Gang; He,Xiang‑Lei; Zhou,Yong‑Lie

doi:10.3892/ol.2016.4279

April-2016 Volume 11 Issue 4

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April-2016 Volume 11 Issue 4

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Case Report

Secondary B-cell lymphoma diagnosed by fine-needle aspiration cytology and flow cytometry following penile carcinoma: A case report

Authors:
- Huan Wang
- Lian‑Nv Qiu
- Mao Wu
- Wan‑Yuan Chen
- Li‑Gang Ren
- Xiang‑Lei He
- Yong‑Lie Zhou
View Affiliations / Copyright

Affiliations: Department of Laboratory Medicine, People's Hospital of Zhejiang Province, Hangzhou, Zhejiang 310014, P.R. China, Department of Pathology, People's Hospital of Zhejiang Province, Hangzhou, Zhejiang 310014, P.R. China, Department of Urinary Surgery, People's Hospital of Zhejiang Province, Hangzhou, Zhejiang 310014, P.R. China
Pages: 2449-2452
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Published online on: February 25, 2016

https://doi.org/10.3892/ol.2016.4279
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Abstract

The number of studies reporting lymphoma as a secondary tumor has gradually increased. However, few studies have reported that occurrence of lymphoma as a secondary tumor following treatment for penile carcinoma, particularly cases in which the lymphoma was diagnosed by fine‑needle aspiration cytology and flow cytometry. The present study reports the case of a 62‑year‑old male patient who was troubled with frequent urination and repeated chest tightness for 5 years. The diagnosis upon admission was penile carcinoma. Two months subsequent to the tumor removal surgery, enlarged lymph nodes were extracted from the patient using fine‑needle biopsy, to be analyzed using light microscopy and flow cytometry. Smear results indicated a large number of abnormal cells scattered in the right axillary lymph node. Flow cytometry immunophenotyping of fine‑needle aspiration samples indicated the increased expression of cluster of differentiation (CD)79a, CD19, CD20, CD38, κ chain and human leukocyte antigen‑DR, which supported a diagnosis of B‑cell lymphoma. Thus, the patient was diagnosed with B‑cell lymphoma based on the results of the fine‑needle aspiration biopsy and flow cytometry. The method of diagnosis and causes of therapy‑related leukemia are discussed in the present report.

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Journals

International Journal of Molecular Medicine

International Journal of Oncology

Molecular Medicine Reports

Oncology Reports

Experimental and Therapeutic Medicine

Oncology Letters

Biomedical Reports

Molecular and Clinical Oncology

World Academy of Sciences Journal

International Journal of Functional Nutrition

International Journal of Epigenetics

Medicine International

Secondary B-cell lymphoma diagnosed by fine-needle aspiration cytology and flow cytometry following penile carcinoma: A case report

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