A case report of gastric cancer with brain metastasis: Rare peripheral nervous system symptoms

Yang,Ge‑Liang; Luo,Tian‑Hang; Zhang,Hui‑Qing; Ling,Chang‑Quan; Li,Bai

doi:10.3892/ol.2016.4288

A case report of gastric cancer with brain metastasis: Rare peripheral nervous system symptoms

Authors:
- Ge‑Liang Yang
- Tian‑Hang Luo
- Hui‑Qing Zhang
- Chang‑Quan Ling
- Bai Li
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Affiliations: Department of Integrative Oncology, Changhai Hospital, Second Military Medical University, Shanghai 200433, P.R. China, Department of General Surgery, Changhai Hospital, Second Military Medical University, Shanghai 200433, P.R. China
Published online on: March 1, 2016 https://doi.org/10.3892/ol.2016.4288
Pages: 2893-2895

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Abstract

Gastric cancer with brain metastasis is rare. The present study reports a case of gastric cancer with isolated brain metastasis 1 year after gastrectomy. To the best of our knowledge, there have been no prior reports of solitary brain metastasis from gastric cancer with peripheral nervous system symptoms. A distal gastrectomy was performed on a 60‑year‑old male patient with gastric cancer in November 2012. Postoperative pathological analysis revealed a moderately differentiated adenocarcinoma with tumor invasion into the serosa and metastasis to one dissected lymph node. No abnormalities were found at follow‑up examination. However, a tumor representing metastasis to the brain was recognized by a cranial enhanced magnetic resonance imaging examination 1 year after gastrectomy, which was performed when the patient exhibited numbness and thigmesthesia. The patient was administered 30 Gy of stereotactic radiotherapy, delivered in 5 fractions. The patient succumbed to disease 10 months subsequent to undergoing radiotherapy. This case report suggests that gastric cancer may re‑present as brain metastasis with peripheral nervous system symptoms.

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