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Case Report Open Access

Pathological complete response following neoadjuvant radiotherapy and intraperitoneal perfusion chemotherapy for recurrent colon carcinoma: A case report and literature review

  • Authors:
    • Xinyu Bian
    • Baorui Liu
    • Yang Yang
  • View Affiliations / Copyright

    Affiliations: The Comprehensive Cancer Centre of Drum Tower Hospital, Medical School of Nanjing University and Clinical Cancer Institute of Nanjing University, Nanjing, Jiangsu 210008, P.R. China
    Copyright: © Bian et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Pages: 2747-2750
    |
    Published online on: March 2, 2016
       https://doi.org/10.3892/ol.2016.4299
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Abstract

The present study reports the case of a 28‑year‑old male who was diagnosed with sigmoid colon carcinoma and exhibited local recurrence following radical surgery and 6 cycles of adjuvant chemotherapy. The primary surgery consisted of a partial sigmoidectomy and bladder repair. At 8 months post‑chemotherapy, the patient was referred to Nanjing Drum Tower Hospital (Nanjing, China) due to local recurrence at the anastomotic site, which was confirmed by colonoscopy and total abdominal computed tomography. Synchronous intensity modulation radiation therapy and intraperitoneal (IP) perfusion chemotherapy with irinotecan (100 mg/m2) was administered. Following treatment, the object efficacy evaluation revealed a complete response and a second resection of the remaining sigmoid colon was performed. The post‑operative results showed a pathological complete response. This case indicated that a combination of therapies, including radiotherapy, IP perfusion chemotherapy and surgery, may be beneficial and effective in patients with recurrent colon cancer.
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Copy and paste a formatted citation
Spandidos Publications style
Bian X, Liu B and Yang Y: Pathological complete response following neoadjuvant radiotherapy and intraperitoneal perfusion chemotherapy for recurrent colon carcinoma: A case report and literature review. Oncol Lett 11: 2747-2750, 2016.
APA
Bian, X., Liu, B., & Yang, Y. (2016). Pathological complete response following neoadjuvant radiotherapy and intraperitoneal perfusion chemotherapy for recurrent colon carcinoma: A case report and literature review. Oncology Letters, 11, 2747-2750. https://doi.org/10.3892/ol.2016.4299
MLA
Bian, X., Liu, B., Yang, Y."Pathological complete response following neoadjuvant radiotherapy and intraperitoneal perfusion chemotherapy for recurrent colon carcinoma: A case report and literature review". Oncology Letters 11.4 (2016): 2747-2750.
Chicago
Bian, X., Liu, B., Yang, Y."Pathological complete response following neoadjuvant radiotherapy and intraperitoneal perfusion chemotherapy for recurrent colon carcinoma: A case report and literature review". Oncology Letters 11, no. 4 (2016): 2747-2750. https://doi.org/10.3892/ol.2016.4299
Copy and paste a formatted citation
x
Spandidos Publications style
Bian X, Liu B and Yang Y: Pathological complete response following neoadjuvant radiotherapy and intraperitoneal perfusion chemotherapy for recurrent colon carcinoma: A case report and literature review. Oncol Lett 11: 2747-2750, 2016.
APA
Bian, X., Liu, B., & Yang, Y. (2016). Pathological complete response following neoadjuvant radiotherapy and intraperitoneal perfusion chemotherapy for recurrent colon carcinoma: A case report and literature review. Oncology Letters, 11, 2747-2750. https://doi.org/10.3892/ol.2016.4299
MLA
Bian, X., Liu, B., Yang, Y."Pathological complete response following neoadjuvant radiotherapy and intraperitoneal perfusion chemotherapy for recurrent colon carcinoma: A case report and literature review". Oncology Letters 11.4 (2016): 2747-2750.
Chicago
Bian, X., Liu, B., Yang, Y."Pathological complete response following neoadjuvant radiotherapy and intraperitoneal perfusion chemotherapy for recurrent colon carcinoma: A case report and literature review". Oncology Letters 11, no. 4 (2016): 2747-2750. https://doi.org/10.3892/ol.2016.4299
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